scholarly journals The influence of low-level laser therapy on biomodulation of collagen and elastic fibers

2003 ◽  
Vol 17 (4) ◽  
pp. 307-313 ◽  
Author(s):  
Lívia Souza Pugliese ◽  
Alena Peixoto Medrado ◽  
Sílvia Regina de Almeida Reis ◽  
Zilton de Araújo Andrade
Keyword(s):  
Wound Healing ◽  
Laser Therapy ◽  
Statistical Significance ◽  
Healing Process ◽  
Low Level Laser Therapy ◽  
Elastic Fibers ◽  
Wound Healing Process ◽  
Low Level ◽  
Low Level Laser ◽  
Level Laser

The study of low-level laser therapy upon extracellular matrix elements is important to understand the wound healing process under this agent. However, little is known about the interference of laser light in relation to collagen and elastic fibers. Cutaneous wounds were performed on the back of 72 Wistar rats and a Ga-Al-As low-level laser was punctually applied with different energy densities. The animals were killed after 24, 48, 72 hours and 5, 7 and 14 days. Tissues were stained with hematoxilin-eosin, sirius red fast green and orcein and then analyzed. It was observed that the treated group exhibited larger reduction of edema and inflammatory infiltrate. The treated animals presented a larger expression of collagen and elastic fibers, although without statistical significance (p > 0.05). Treatment with a dosage of 4 J/cm² exhibited more expressive results than that with 8 J/cm². In this study, the authors concluded that low-level laser therapy contributed to a larger expression of collagen and elastic fibers during the early phases of the wound healing process.

scholarly journals Low level laser therapy and its effects on reparatory processes of the skin

2003 ◽  
Vol 56 (3-4) ◽  
pp. 137-141 ◽  
Author(s):  
Milan Matic ◽  
Bogosav Lazetic ◽  
Mirjana Poljacki ◽  
Verica Djuran ◽  
Milana Ivkov-Simic
Keyword(s):  
Wound Healing ◽  
Laser Radiation ◽  
Laser Therapy ◽  
Healing Process ◽  
Low Level Laser Therapy ◽  
Wound Healing Process ◽  
Low Level ◽  
Low Level Laser ◽  
Level Laser ◽  
Laser Devices

Introduction Application of laser beams for therapeutic purposes is of relatively recent date, but today there is no field of medicine where lasers cannot be used. Physical characteristics of laser radiation Laser radiation is a type of electromagnetic radiation with some specific characteristics such as coherence, monochromaticity and parallelity. Types of laser devices Nowadays, there are many laser devices on the market used in medicine and dentistry. According to the type of their active medium, lasers can be classified as solid, gas, semiconductor and liquid. Effects of low level laser therapy on biological systems The exact mechanism of action of low level laser therapy is still not completely understood. Its basic feature is to modulate cell behaviour, without causing significant temperature increase. During irradiation of a tissue with a laser beam, an interaction between cells and photons takes place - photochemical reaction. After a cell absorbs the photon, the photon stops existing, and its energy is incorporated into the molecule which has absorbed it. Once this energy is transferred to different bio-molecules, it can be transferred to other molecules as well. The energy transferred to the molecule can increase its kinetic energy, and activate or deactivate enzymes or alter physical or chemical properties of main macromolecules. Effects of low level laser therapy on wound healing Effects of low level laser therapy on wound healing process is one of the most fully studied aspects of this type of therapy. It affects all phases of this very complex process. This paper offers a more detailed analysis of these aspects.

scholarly journals The effect of low-level laser therapy and stress on wound healing in rats

2021 ◽  
Author(s):  
Mohsen Dalband ◽  
Shahabaldin Azizi ◽  
Mahdieh Karimzadeh ◽  
Mohammad Asnaashari ◽  
Abdullah Farhadinasb ◽  
...  
Keyword(s):  
Wound Healing ◽  
Laser Therapy ◽  
Healing Process ◽  
Low Level Laser Therapy ◽  
Wound Healing Process ◽  
Stress And Strain ◽  
Low Level ◽  
Low Level Laser ◽  
Level Laser ◽  
Significant Difference

Background: Many studies have been performed on the effect of low level laser on wound healing which has been associated with different and sometimes contradictory results. On the other hand, considering that stress may affect the immune system the fact that it may delay wound healing has also been addressed. Therefore, the present study aimed to investigate the simultaneous effect of low level  laser therapy and stress on wound healing at the three levels of histology (histological changes), biomechanics (stress and strain assessment) and macroscopic (wound size). Methods: In this interventional study, 72 male Wistar rats (8-10 weeks old, weight range: 240 to 330 g) were randomly divided into three treatment groups and one control group. (18 per group). In all the rats, a 2.5 cm full-thickness skin incision was made on the dorsal spine. Intervention was performed from day 1 to day 21 every other day with Kals-DX61 laser (cap s) with wavelength: 660 nm, dose 3 J / cm2, 100 sec and power density 30 mW / cm2. Then, wound size was measured weekly until the third week (day 21). Then, tension metric tests were performed to evaluate the stress and strain of the restored tissue. At the end of each week, three animals from each group were sacrificed for histopathological evaluation. Results: There was a significant difference between the stress / no laser and laser/no stress groups in all stages of evaluation. Mean and standard deviation of stress and strain were not significantly different in the study groups. Conclusion: Stress can potentially slow the wound healing process, while receiving low level laser therapy speeds up the wound healing process, although in the end there was no significant difference in biomechanical characteristics between the groups.

scholarly journals THE “LASEPRF”- LASER TREATED PRF FOR TREATMENT OF MULTIPLE GINGIVAL RECESSIONS - A CASE REPORT

2020 ◽  
Vol 9 (3) ◽  
Author(s):  
Keerthi.K.L ◽  
P.Aravind Kumar ◽  
M. Narendra Babu ◽  
K.Raviraj
Keyword(s):  
Wound Healing ◽  
Laser Therapy ◽  
Healing Process ◽  
Gingival Recession ◽  
Low Level Laser Therapy ◽  
Root Coverage ◽  
Platelet Rich Fibrin ◽  
Low Level ◽  
Low Level Laser ◽  
Level Laser

Treatment of gingival recession has become an important therapeutic issue due to increasing cosmetic demand. Multiple surgical procedures have been developed to obtain predictable esthetic root coverage.. Low level laser therapy (LLLT) has biostimulative effect on platelets by inducing platelet degranulation. Therefore, it can be possible that the use of Platelet rich fibrin (PRF) treated with LLLT could help in increasing the concentration of growth factors in the wound healing, thus accelerates healing process. This paper reports the use of PRF treated with laser for root coverage on the labial surfaces of the maxillary right teeth. Keywords: Low level laser therapy (LLLT), Platelet rich fibrin (PRF), Modified VISTA technique.

scholarly journals Effects of low-level laser therapy on the healing of foot ulcers in people with diabetes mellitus

2020 ◽  
Author(s):  
Maria Girlane Sousa Albuquerque Brandão ◽  
Maria Aline Moreira Ximenes ◽  
Aline de Oliveira Ramalho ◽  
Vivian Saraiva Veras ◽  
Lívia Moreira Barros ◽  
...  
Keyword(s):  
Laser Therapy ◽  
Diabetic Foot ◽  
Healing Process ◽  
Low Level Laser Therapy ◽  
Limb Amputation ◽  
Wound Healing Process ◽  
Eligibility Criteria ◽  
Low Level ◽  
Low Level Laser ◽  
Level Laser

Objective: Identify the effects of low-level laser therapy on the healing of diabetic foot. Method: Systematic review of the PubMed, LILACS, SciELO, CINAHL, Cochrane, Web of Science and Scopus databases, in which 92 articles were identified and six were included in the final sample after the eligibility criteria. Results: The articles pointed out as effects of laser therapy the effectiveness in the progression of the tissue repair process of the diabetic foot, pain relief, anti-inflammatory action, increased tissue perfusion of the lesion and improvement of the vascular response and the nervous system. Conclusion: Laser is an adjuvant therapy that can accelerate the wound healing process, relieve pain, improve neovascularization, and thus minimize the risk of complications, such as lower limb amputation and improvement of quality of life for people with diabetes and impaired skin integrity.

Wound-healing effects of low-level laser therapy in diabetic rats involve the modulation of MMP-2 and MMP-9 and the redistribution of collagen types I and III

2013 ◽  
Vol 15 (4) ◽  
pp. 210-216 ◽  
Author(s):  
Andreia Aparecida Da Silva ◽  
Ernesto Cesar Pinto Leal-Junior ◽  
Ana Carolina Araruna Alves ◽  
Caroline Sobral Rambo ◽  
Solange Almeida Dos Santos ◽  
...  
Keyword(s):  
Wound Healing ◽  
Laser Therapy ◽  
Diabetic Rats ◽  
Low Level Laser Therapy ◽  
Collagen Types ◽  
Low Level ◽  
Low Level Laser ◽  
Level Laser

scholarly journals Effect of low-level laser therapy on wound healing after depigmentation procedure: A clinical study

2016 ◽  
Vol 0 (0) ◽  
pp. 0 ◽  
Author(s):  
Kirti Chawla ◽  
ArundeepKaur Lamba ◽  
Shruti Tandon ◽  
Farrukh Faraz ◽  
Varun Gaba
Keyword(s):  
Wound Healing ◽  
Clinical Study ◽  
Laser Therapy ◽  
Low Level Laser Therapy ◽  
Low Level ◽  
Low Level Laser ◽  
Level Laser

Low-Level Laser-Assisted Liposuction: A Multicenter Side-by-Side Comparison Study

2003 ◽  
Vol 20 (2) ◽  
pp. 97-102 ◽  
Author(s):  
Edward B. Lack ◽  
Kimberly J. Butterwick ◽  
Neil Sadick
Keyword(s):  
Wound Healing ◽  
Laser Therapy ◽  
Local Anesthesia ◽  
The United States ◽  
Low Level Laser Therapy ◽  
Tumescent Technique ◽  
Postoperative Course ◽  
Low Level ◽  
Low Level Laser ◽  
Level Laser

Introduction: Liposuction has undergone many revisions since 1980, the most notable being the introduction of the tumescent technique of local anesthesia by Jeffery Klein, MD. Since then, in an effort to improve the aesthetics of the technique and the ease and safety of the procedure, other techniques have been introduced. These include superficial liposuction, UAL, external ultrasonic liposuction, mechanically assisted liposuction, and, most recently, laser-assisted liposuction. Materials and Methods: Four centers in the United States, operating under an 1RB protocol, performed liposuction with the tumescent technique of local anesthesia on specified cosmetic units of the body. One side was exposed to 635-nm laser therapy after tumescence was achieved, whereas the contralateral side was not. Observations were recorded during surgery and at 2 weeks postoperatively. Results: Observations of intraoperative technique did not show an advantage to laser-assisted liposuction. Observations of the postoperative course were equivocal, though there was evidence of reduction of edema in certain patients. Discussion: The addition of laser therapy to liposuction technique is based on years of experience demonstrating improved wound healing using a technique of low-level laser therapy. Although the recorded observations did not support an advantage to the addition of laser therapy, there was a paradoxical difference of opinion among patients and surgeons who participated in the study. These individuals believed that, compared with patients not treated with low-level laser therapy, there was at least a reduction in degree and duration of postoperative pain and induration. As low-level laser therapy may have systemic effects on wound healing, comparing treated and untreated contralateral sides may not be valid because both sides experienced improvements in postoperative course. Laser-assisted liposuction has a potential advantage, not supported by this study, in the intraoperative and postoperative course of liposuction surgery. New studies using double-blind techniques will need to be conducted.

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