scholarly journals Hyperammonemic Encephalopathy Associated With Fibrolamellar Hepatocellular Carcinoma: Case Report, Literature Review, and Proposed Treatment Algorithm

2016 ◽  
Vol 21 (4) ◽  
pp. 514-520 ◽  
Author(s):  
Claudia I. Chapuy ◽  
Inderneel Sahai ◽  
Rohit Sharma ◽  
Andrew X. Zhu ◽  
Olga N. Kozyreva
2019 ◽  
Vol 10 (3) ◽  
pp. 582-588 ◽  
Author(s):  
Janice Cho ◽  
Joy C. Y. Chen ◽  
Jonas Paludo ◽  
Erin E. Conboy ◽  
Brendan C. Lanpher ◽  
...  

Pathology ◽  
2017 ◽  
Vol 49 ◽  
pp. S80
Author(s):  
Harini Narayanappa ◽  
Catriona McKenzie ◽  
Charbel Sandroussi ◽  
Sunaina Anand

2018 ◽  
Vol 2018 ◽  
pp. 1-6 ◽  
Author(s):  
Oscar Suarez ◽  
María Perez ◽  
Martin Garzon ◽  
Rodrigo Daza ◽  
Geovanny Hernandez ◽  
...  

Fibrolamellar hepatocarcinoma is an infrequent liver tumor, currently considered to be a variant different from hepatocarcinoma. The differences lie in genomic alterations, a greater prevalence of fibrolamellar hepatocarcinoma in young patients, and its lack of association with underlying liver disease. The clinical presentation is unspecific, with symptoms ranging from abdominal pain, malaise, and weight loss to atypical manifestation which include hyperammonemic encephalopathy. We present the case of a 33-year-old woman with no prior medical history who presented with a coma and a diagnosis of inoperable fibrolamellar hepatocarcinoma requiring a cadaver donor transplant. While she was on the waiting list, she received hemofiltration and ammonium benzoate treatment, with progressive improvement in her state of consciousness.


Sign in / Sign up

Export Citation Format

Share Document