scholarly journals Peri-implant soft tissue augmentation with a porcine collagen matrix.

2014 ◽  
Vol 3 (4) ◽  
pp. 244-248
Author(s):  
Yuri Castro ◽  
Silvana Grados ◽  
Sixto Grados
Materials ◽  
2019 ◽  
Vol 12 (22) ◽  
pp. 3721 ◽  
Author(s):  
Jordi Caballé-Serrano ◽  
Sophia Zhang ◽  
Luca Ferrantino ◽  
Massimo Simion ◽  
Vivianne Chappuis ◽  
...  

A short inflammatory phase and fast ingrowth of blood vessels and mesenchymal cells are essential for tissue integration of a biomaterial. Macrophages play a key role in this process. We investigated invasion of macrophages, blood vessels, and proliferating cells into a highly porous and volume-stable collagen matrix (VCMX) used for soft tissue augmentation around teeth and dental implants. The biomaterial was implanted in submucosal pouches in the canine maxilla, and the tissue response was analyzed at six different time points. Immunohistochemistry was done for proliferating cells (PCNA), macrophages (MAC387), multinucleated giant cells (CD86), and blood vessels (TGM2). Blood rapidly filled the VCMX pores. During the first week, MAC387+ cells populated the VCMX pores, blood vessels and PCNA+ cells invaded the VCMX, and CD86+ scattered cells were observed. At 15 days, MAC387+ cells were scanty, blood vessels had completely invaded the VCMX, the number of proliferating cells peaked, and fibroblasts appeared. At 30 days, MAC387+ were absent, the numbers of proliferating and CD86+ cells had declined, while blood vessel and fibroblast numbers were high. At 90 days, residual VCMX was well-integrated in soft connective tissue. In conclusion, the VCMX elicited a short inflammatory phase followed by rapid tissue integration.


2016 ◽  
Vol 36 (6) ◽  
pp. 807-815 ◽  
Author(s):  
Luca Ferrantino ◽  
Dieter Bosshardt ◽  
Myron Nevins ◽  
Giacomo Santoro ◽  
Massimo Simion ◽  
...  

Materials ◽  
2020 ◽  
Vol 14 (1) ◽  
pp. 93
Author(s):  
Mario Beretta ◽  
Carlo Maiorana ◽  
Mattia Manfredini ◽  
Susanna Ferrario ◽  
Pier Paolo Poli

The quality and quantity of peri-implant soft tissues at the crestal portion of dental implants are important aspects to consider for a long-term successful implant-supported rehabilitation. Some relevant factors attributed to the implant health include mucosal thickness and keratinization. In this respect, many techniques and materials have been described to augment and improve buccal peri-implant soft tissues. Over the last few years, newly developed xenogeneic collagen matrices have been introduced in peri-implant plastic surgery to replace autogenous soft tissue grafts; however, data remain controversial so far. Thus, the purpose of the present report was to present a novel surgical technique conceived to augment buccal peri-implant soft tissues in combination with a volume-stable porcine collagen matrix. The rationale and the fundamental concepts that led to the use of a xenogeneic matrix to increase soft tissue volumes were also discussed.


2021 ◽  
Vol 19 (4) ◽  
pp. 317-319
Author(s):  
A. B. Adzhieva ◽  
I. A. Voronov ◽  
S. S. Ivanov ◽  
H. M. Nalchajyan

Lack of adequate width and thickness of periodontal or peri-implant soft tissues can compromise the aesthetics, function or survival of teeth and dental implants. Biomaterials are widely used in dentistry to overcome the disadvantages of autogenous tissue transplantation. The advantage of using biomaterials is that there is no need for re-surgery and that they are available in large quantities. The most widely used biomaterial for soft tissue augmentation is collagen, as it is believed to best mimic the natural cellular environment of the extracellular matrix, although other biomaterials are also candidates for soft tissue regeneration. Collagen matrices differ in composition, three-dimensional structure, elasticity and mechanical stability. Aim. is to review the literature on the optimization of regeneration at the stages of soft tissue augmentation using a collagen matrix.


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