Method for Establishment and transfer of classical eyeblink conditioning using electrical microstimulation of the hippocampus as the conditioned stimulus v1 (protocols.io.hsib6ce)

protocols.io ◽  
2017 ◽  
Author(s):  
Jian feng

PLoS ONE ◽  
2017 ◽  
Vol 12 (6) ◽  
pp. e0178502
Author(s):  
Juan Yao ◽  
Bing Wu ◽  
Guang-yan Wu ◽  
Xuan Li ◽  
Jian-ning Ye ◽  
...  


2019 ◽  
Vol 359 ◽  
pp. 149-155
Author(s):  
Lang-Qian Zhang ◽  
Juan Yao ◽  
Jie Gao ◽  
Lin Sun ◽  
Li-Ting Wang ◽  
...  




2010 ◽  
Vol 103 (3) ◽  
pp. 1329-1336 ◽  
Author(s):  
Pär Svensson ◽  
Dan-Anders Jirenhed ◽  
Fredrik Bengtsson ◽  
Germund Hesslow

Pavlovian eyeblink conditioning is a useful experimental model for studying adaptive timing, an important aspect of skilled movements. The conditioned response (CR) is precisely timed to occur just before the onset of the expected unconditioned stimulus (US). The timing can be changed immediately, however, by varying parameters of the conditioned stimulus (CS). It has previously been shown that increasing the intensity of a peripheral CS or the frequency of a CS consisting of a train of stimuli to the mossy fibers shortens the latency of the CR. The adaptive timing of behavioral CRs probably reflects the timing of an underlying learned inhibitory response in cerebellar Purkinje cells. It is not known how the latency of this Purkinje cell CR is controlled. We have recorded form Purkinje cells in conditioned decerebrate ferrets while increasing the intensity of a peripheral CS or the frequency of a mossy fiber CS. We observe changes in the timing of the Purkinje cell CR that match the behavioral effects. The results are consistent with the effect of CS parameters on behavioral CR latency being caused by corresponding changes in Purkinje cell CRs. They suggest that synaptic temporal summation may be one of several mechanisms underlying adaptive timing of movements.



2017 ◽  
Vol 131 (2) ◽  
pp. 149-154
Author(s):  
Matthew M. Campolattaro ◽  
Sean W. Savage ◽  
Olga Lipatova






2014 ◽  
Vol 274 ◽  
pp. 19-29 ◽  
Author(s):  
Juan Yao ◽  
Guang-yan Wu ◽  
Guo-long Liu ◽  
Shu-lei Liu ◽  
Yi Yang ◽  
...  


2007 ◽  
Vol 14 (3) ◽  
pp. 152-159 ◽  
Author(s):  
M. M. Campolattaro ◽  
H. E. Halverson ◽  
J. H. Freeman


Sign in / Sign up

Export Citation Format

Share Document