scholarly journals A clinical case of treatment of a patient with laryngeal granular cell (Abrikossoff) tumor

2021 ◽  
Vol 11 (3) ◽  
pp. 104-108
Author(s):  
Z. A.‑G. Radzhabova ◽  
M. A. Kotov ◽  
M. A. Radzhabova ◽  
O. I. Ponomareva ◽  
A. S. Artemieva ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Clinical Case ◽  
Granular Cell Tumor ◽  
Cricoid Cartilage ◽  
Granular Cell ◽  
Cell Tumor ◽  
Study Objective ◽  
Well Differentiated

The study objective – present a clinical case of radical surgical treatment of a laryngeal granular cell tumor with invasion of cricoid cartilage and thyroid gland and show the importance of pathomorphological diagnosis.Case report. A 47‑year-old woman of European origin complained of progressive hoarseness that lasted for 8 months. We analyzed her clinical, laboratory, radiological, and pathomorphological data. At the preoperative stage, the tumor was classified as well differentiated squamous cell carcinoma (stage cT4aN0M0). Endoscopic examination revealed the exophytic part of the tumor with an infiltrative base and tuberous surface, pinkish, with signs of dyskeratosis and tumor invasion to the cartilage. Pathomorphological examination of biopsy specimens demonstrated well differentiated keratinizing squamous cell carcinoma. The patient has undergone laryngectomy, thyroidectomy, and selective cervical lymph node dissection. Pathomorphological and immunohistochemical examinations of surgical material verified granular cell tumor of the larynx (Abrikosov’s tumor) that was excised within healthy tissues (R0). Conclusion. The presented clinical case of such a rare pathology as a granular cell tumor of the larynx shows the importance of pathomorphological diagnosis and the use of additional immunohistochemical research methods for making an accurate diagnosis and differential diagnosis of squamous cell carcinoma and Abrikossoff tumor.  

Esophageal granular cell tumor covered by intramucosal squamous cell carcinoma: Report of a case

Surgery Today ◽  
2008 ◽  
Vol 38 (7) ◽  
pp. 651-655 ◽  
Author(s):  
Kana Saito ◽  
Hiroyuki Kato ◽  
Yasuyuki Fukai ◽  
Hitoshi Kimura ◽  
Tatsuya Miyazaki ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Granular Cell Tumor ◽  
Granular Cell ◽  
Cell Tumor

Coexistent Squamous Cell Carcinoma and Granular Cell Tumor of Head and Neck Region: Report of Two Very Rare Cases and Review of the Literature

2017 ◽  
Vol 26 (1) ◽  
pp. 47-51 ◽  
Author(s):  
Danila Caroppo ◽  
Grazia Salerno ◽  
Francesco Merolla ◽  
Massimo Mesolella ◽  
Gennaro Ilardi ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Head And Neck ◽  
Squamous Cell ◽  
Granular Cell Tumor ◽  
Neck Region ◽  
Granular Cell ◽  
Cell Tumor ◽  
Head And Neck Region ◽  
Pathologic Features

Granular cell tumor (GCT), a relatively rare neuroectodermal tumor occurring most often in the head and neck region, is not uncommonly associated with pseudoepitheliomatous hyperplasia of the overlying surface epithelium, which may be at times nonreadily distinguishable from well-differentiated squamous cell carcinoma (SCC). To the best of our knowledge, only a handful of coexisting SCC and GCT, mostly described in the esophagus, have been reported in (the current) literature so far. We herein report 2 new cases of coexisting GCT and SCC of the head and neck region, located, respectively, in larynx and tongue; comment on their clinical, imaging, and pathologic features; and discuss their management. In the present work, we also review the literature concerning this association to contribute to the head and neck pathologists’ and surgeons’ awareness regarding the possibility of this association for an adequate surgical excision and a better management of these patients.

Granular Cell Tumors of the Larynx

1976 ◽  
Vol 85 (4) ◽  
pp. 504-507 ◽  
Author(s):  
Harvey L. Coates ◽  
Thomas J. McDonald ◽  
Kenneth D. Devine ◽  
Louis H. Weiland
Keyword(s):  
Squamous Cell Carcinoma ◽  
Differential Diagnosis ◽  
Cell Carcinoma ◽  
Local Excision ◽  
Squamous Cell ◽  
Granular Cell Tumor ◽  
Granular Cell ◽  
Cell Tumor ◽  
Posterior Portion ◽  
Pseudoepitheliomatous Hyperplasia

Granular cell tumors of the larynx are relatively uncommon, always benign, and most commonly located in the posterior portion of the larynx. They are easily identified and should be differentiated from other lesions. A possible problem in the differential diagnosis is the presence of pseudoepitheliomatous hyperplasia, which overlies the granular cell tumor and which may mimic squamous cell carcinoma. Careful histopathologic differentiation is important because the laryngeal granular cell lesion should be managed conservatively, with transoral local excision usually being adequate. The histogenesis of these lesions remains in doubt, with a neural or epithelial derivation being the most likely possibility.

scholarly journals Lingual Squamous Cell Carcinoma Surrounded by Granular Cell Tumor

2012 ◽  
Vol 48 (1) ◽  
pp. 65 ◽  
Author(s):  
Hee Young Son ◽  
Jin Pyeong Kim ◽  
Gyung Hyuck Ko ◽  
Eun Jae Lee ◽  
Seung Hoon Woo
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Granular Cell Tumor ◽  
Granular Cell ◽  
Cell Tumor

scholarly journals Granular cell tumor mimicking a squamous cell carcinoma of the tongue: a case report

2017 ◽  
Vol 10 (1) ◽  
Author(s):  
Jean Carlos Barbosa Ferreira ◽  
Angélica Ferreira Oton-Leite ◽  
Rafaela Guidi ◽  
Elismauro Francisco Mendonça
Keyword(s):  
Squamous Cell Carcinoma ◽  
Case Report ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Granular Cell Tumor ◽  
Granular Cell ◽  
Cell Tumor ◽  
Carcinoma Of The Tongue

Benign Granular Cell Tumors of the Larynx: A Review of 36 Cases with Clinicopathologic Data

1975 ◽  
Vol 84 (3) ◽  
pp. 308-314 ◽  
Author(s):  
John Compagno ◽  
Vincent J. Hyams ◽  
Pierre Ste-Marie
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Vocal Cord ◽  
Granular Cell Tumor ◽  
Squamous Epithelium ◽  
Granular Cell ◽  
Cell Tumor ◽  
Clinical Impression ◽  
True Vocal Cord

The clinical, microscopic, and gross features of 36 cases of benign granular cell tumor arising in the larynx are reviewed and studied. This infrequent lesion, when in the larynx, is found most commonly on the true vocal cord in adults in their third, fourth, and fifth decades; there is no obvious sex predilection. Slowly increasing hoarseness was the primary complaint in our cases. Clinically, the tumors are considered benign. The most common clinical impression was a vocal cord papilloma. The microscopic pattern of the granular cell tumors is uniform and bland, but there may be a marked pseudoepitheliomatous hyperplasia of the overlying squamous epithelium, often stimulating squamous cell carcinoma. Follow-up information is discussed, as is the origin and histogenesis of this lesion.

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