scholarly journals Undifferentiated Carcinoma of Pancreas Presenting as Obstructive Jaundice

2021 ◽  
pp. 152-155
Author(s):  
A Sekaran ◽  
S Koppula ◽  
DN Reddy ◽  
S Lakhtakia ◽  
B Patodiya
2019 ◽  
Vol 6 (6) ◽  
pp. 1876
Author(s):  
Zubair Afzal Khan

Background: There are various causes of obstructive jaundice, choledocholithiasis– the commonest. Patients with obstructive jaundice usually present with complain of yellow skin and eyes, pale stools, dark coloured urine, jaundice, and pruritus.Abdominal pain often misleading for diagnosis. The objectives of the study were to study the clinical profile of patients with obstructive jaundice.Methods: The study included the patients clinically diagnosed as suffering from obstructive jaundice. Thorough history taking and clinical examination was done. Patients undergone for various laboratory investigations, and radiological evaluation.Results: A total 201 patients were included in the present study. Males are more affected (55.72%) as compared to females. Elder age groups (>65 years; and 55-65 years) were commonly affected. 58.71% of patients have malignant causes for development of obstructive jaundice as compared to benign causes in 41.29% of patients. Choledocholithiasis (30.35%) is the commonest cause of obstructive jaundice followed by carcinoma of pancreas (25.87%). Jaundice is the commonest symptom of presentation.Conclusions: Better understanding of the clinical profile in the patients with obstructive jaundice will facilitate appropriate management and lead to improved survival.


2013 ◽  
Vol 108 ◽  
pp. S241-S242
Author(s):  
Kabir Ahmed ◽  
Douglas Lynch ◽  
Gary Timmerman ◽  
Kimberlee Tams ◽  
Kristin DeBerg ◽  
...  

2020 ◽  
Vol 10 (1) ◽  
pp. 1687-1690
Author(s):  
Lakshmi Priya Unnikrishnan ◽  
Noushad Babu PK ◽  
Asiq Sideeque

Undifferentiated carcinoma of pancreas with osteoclastic giant cells is a rare tumor. The prognosis is slightly better than usual anaplastic carcinoma. It is said to have an epithelial origin. We present a case of 61-year-old female who presented with features of cholangitis and on evaluation found to have pancreatic mass. Pancreatic intraepithelial neoplasia was also present in our case, which is a feature less commonly noted in published literature.


HPB ◽  
2020 ◽  
Vol 22 ◽  
pp. S120
Author(s):  
R. Misawa ◽  
A. Masi ◽  
Z. Moghadamyeghaneh ◽  
N. Fung ◽  
A. Gruessner ◽  
...  

Author(s):  
S. Shirahama ◽  
G. C. Engle ◽  
R. M. Dutcher

A transplantable carcinoma was established in North West Sprague Dawley (NWSD) rats by use of X-irradiation by Engle and Spencer. The tumor was passaged through 63 generations over a period of 32 months. The original tumor, an adenocarcinoma, changed into an undifferentiated carcinoma following the 19th transplant. The tumor grew well in NWSD rats of either sex at various ages. It was invariably fatal, causing death of the host within 15 to 35 days following transplantation.Tumor, thymus, spleen, and plasma from 7 rats receiving transplants of tumor at 3 to 9 weeks of age were examined with an electron microscope at intervals of 8, 15, 22 and 30 days after transplantation. Four normal control rats of the same age were also examined. The tissues were fixed in glutaraldehyde, postfixed in osmium tetroxide and embedded in Epon. The plasma was separated from heparanized blood and processed as previously described for the tissue specimens. Sections were stained with uranyl acetate followed by lead citrate and examined with an RCA EMU-3G electron microscope.


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