Acute symptomatic seizures during haematopoietic stem cell transplantation

Acute symptomatic epileptic seizures are one of the complications of hematopoietic stem cell transplantation. The etiological factors leading to the development of this complication differ from those in the general population, while the significance of each of them is different depending on the time after transplantation. We analyze the literature data on the role of drugs, metabolic disorders and infectious complications, as well as the structural pathology of the brain substance in the development of acute symptomatic seizures in patients with oncohematological pathology. We also consider the clinical features of symptomatic epileptic seizures and the possible prognostic significance of their development in patients who underwent hematopoietic stem cell transplantation.

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Late effects on haemostasis after haematopoietic stem cell transplantation

Hämostaseologie ◽

10.5482/ha-1184 ◽

2012 ◽

Vol 32 (01) ◽

pp. 63-66 ◽

Cited By ~ 1

Author(s):

D. A. Tsakiris ◽

G. Stussi

Keyword(s):

Stem Cell ◽

Hematopoietic Stem Cell Transplantation ◽

Stem Cell Transplantation ◽

Cell Transplantation ◽

Hematopoietic Stem Cell ◽

Autologous Transplantation ◽

Haematopoietic Stem Cell ◽

First Year ◽

Hematopoietic Stem ◽

Considerable Morbidity

SummaryAllogeneic and autologous hematopoietic stem cell transplantations are important therapeutic options for patients with hematologic disorders. Hemostatic complications are frequent after hematopoietic stem cell transplantation with a considerable morbidity and mortality. The incidence of bleedings and thrombosis is highest in the first few weeks after transplantation, but may also occur later. However, beyond the first year of transplantation only limited data are available. In longterm survivors the risk for premature atherosclerosis increases over time after allogeneic hematopoietic stem cell transplantation and it is higher than in the age-adjusted general population and in recipients of autologous transplantation.

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Late effects on haemostasis after haematopoietic stem cell transplantation

Onkologische Welt ◽

10.1055/s-0038-1630988 ◽

2012 ◽

Vol 03 (01) ◽

pp. 12-15

Author(s):

A. Tsakiris ◽

G. Stussi

Keyword(s):

Stem Cell ◽

Hematopoietic Stem Cell Transplantation ◽

Stem Cell Transplantation ◽

Cell Transplantation ◽

Hematopoietic Stem Cell ◽

Autologous Transplantation ◽

Haematopoietic Stem Cell ◽

First Year ◽

Hematopoietic Stem ◽

Considerable Morbidity

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Acute abdomen after allogenic haematopoietic stem cell transplantation

Pediatric Reports ◽

10.4081/pr.2011.e32 ◽

2011 ◽

Vol 3 (4) ◽

pp. 32 ◽

Cited By ~ 1

Author(s):

Alessandro Crocoli ◽

Daria Pagliara ◽

Franco Locatelli ◽

Alessandro Inserra

Keyword(s):

Stem Cell ◽

Hematopoietic Stem Cell Transplantation ◽

Stem Cell Transplantation ◽

Acute Abdomen ◽

Cell Transplantation ◽

Hematopoietic Stem Cell ◽

Haematopoietic Stem Cell Transplantation ◽

Conservative Therapy ◽

Haematopoietic Stem Cell ◽

Hematopoietic Stem

We report a case of a patient underwent allogenic hematopoietic stem cell transplantation complicated by acute colonic pseudo obstruction who require surgery after failure of conservative therapy.

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Evaluation of Epileptic Seizures Developed During Hematopoietic Stem Cell Transplantation: A Single Center Experience

Acta Oncologica Turcica ◽

10.5505/aot.2021.57805 ◽

2021 ◽

Vol 54 (1) ◽

pp. 40-50

Author(s):

Serhat Çelik ◽

Zeynep Tuğba Güven ◽

Nimet Kübra Özsoy ◽

Ayşe Günay ◽

Muzaffer Keklik ◽

...

Keyword(s):

Stem Cell ◽

Hematopoietic Stem Cell Transplantation ◽

Stem Cell Transplantation ◽

Cell Transplantation ◽

Hematopoietic Stem Cell ◽

Epileptic Seizures ◽

Single Center ◽

Hematopoietic Stem ◽

Single Center Experience

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Epileptic Seizures After Allogeneic Hematopoietic Stem Cell Transplantation

Frontiers in Neurology ◽

10.3389/fneur.2021.675756 ◽

2021 ◽

Vol 12 ◽

Author(s):

Zhuo Wang ◽

Munan Zhao ◽

Sujun Gao

Keyword(s):

Stem Cell ◽

Hematopoietic Stem Cell Transplantation ◽

Stem Cell Transplantation ◽

Cell Transplantation ◽

Hematopoietic Stem Cell ◽

Clinical Manifestations ◽

Epileptic Seizures ◽

Hematopoietic Stem ◽

Number Of Patients ◽

Complex Procedure

Technique in allogeneic hematopoietic stem cell transplantation has greatly advanced over the past decades, which has led to an increase in the number of patients receiving transplantation, but the complex procedure places these transplant recipients at high risk of a large spectrum of complications including neurologic involvement. As a common manifestation of neurological disorders, epileptic seizures after transplantation have been of great concern to clinicians because it seriously affects the survival rate and living quality of those recipients. The aim of this review is to elucidate the incidence of seizures after allogeneic hematopoietic stem cell transplantation, and to further summarize in detail its etiologies, possible mechanisms, clinical manifestations, therapeutic schedule, and prognosis, hoping to improve doctors' understandings of concurrent seizures following transplantation, so they can prevent, process, and eventually improve the survival and outlook for patients in a timely manner and correctly.

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