Orodental, Facial and Clinical Features of Mutation-Positive Noonan Syndrome: A Monocentric Study

2020 ◽  
Vol 44 (4) ◽  
pp. 262-267
Author(s):  
Semra Gürsoy ◽  
Filiz Hazan ◽  
Bülent Kaderli ◽  
Timur Meşe ◽  
Ajlan Tükün
Keyword(s):  
Noonan Syndrome ◽  
Sanger Sequencing ◽  
Open Bite ◽  
Molecular Characteristics ◽  
Class Ii Malocclusion ◽  
Gingival Hyperplasia ◽  
Oral Medicine ◽  
Anterior Open Bite ◽  
Ptpn11 Gene ◽  
High Arched Palate

Objective: To evaluate orodental, facial, clinical and molecular characteristics of the patients with Noonan Syndrome (NS).Study Design: The orodental, clinical and molecular characteristics of 29 mutation-positive patients with NS were recorded. Orodental examination was performed in 17 patients. All exons and exonintron boundries of PTPN11 and SOS1 genes were analyzed by Sanger sequencing. Results: A total of 29 patients with NS from 27 unrelated families were included in the study. Seventeen patients were examined by a specialist in oral medicine. The most common orodental findings were high-arched palate (n=13), gingivitis (n=6) and severe caries (n=6). Anterior open bite, posterior cross bite, Class II malocclusion, hypodontia, prognathism (maxillary or mandibular), macroglossia and gingival hyperplasia were also detected. Thirteen different mutations were observed in PTPN11 gene and exon 3 was the hotspot region. Hypodontia was detected in two patients who had the same mutation in PTPN11 gene, c.181G>A, p.D61N. Conclusion: This study indicated a high prevalance of orodental problems including high-arched palate, severe dental caries and gingivitis in patients with mutation-positive NS. The mutation in PTPN11 gene, c.181G>A, p.D61N, may be associated with hypodontia in patients with NS.

Aversive Taste Treatment of Finger and Thumb Sucking

PEDIATRICS ◽  
1986 ◽  
Vol 78 (1) ◽  
pp. 174-176
Author(s):  
PATRICK C. FRIMAN ◽  
VINCENT J. BARONE ◽  
EDWARD R. CHRISTOPHERSEN
Keyword(s):  
Early Childhood ◽  
Behavior Disorders ◽  
Self Esteem ◽  
Open Bite ◽  
Class Ii Malocclusion ◽  
Anterior Open Bite ◽  
Child Behavior Problem ◽  
Aversive Taste ◽  
Thumb Sucking ◽  
Infancy And Early Childhood

Thumb sucking is common and adaptive in infancy and early childhood. But when sucking occurs beyond 4 years of age, a common result can be an anterior, open bite that requires expensive orthodontic correction.1 Prolonged sucking may also be a factor in class II malocclusion, narrowing of the dental arches, mucosal trauma, and digital malformation.1-4 In addition to the physical sequelae of sucking, the habit, because it is not socially approved, can generate persistent negative feedback which can adversely affect a child's self-esteem.5 Thumb sucking is a frequently reported child behavior problem that, in some children, can be associated with broader behavior disorders that require treatment.

Abordagem precoce da má oclusão de Classe II esquelética com atresia maxilar e mordida aberta anterior e o uso de alinhadores ClearCorrect – relato de caso

2021 ◽  
Vol 14 (53) ◽  
pp. 97-106
Author(s):  
Roberto Hideo Shimizu ◽  
Isabela Almeida Shimizu ◽  
Ana Cláudia M. Melo Toyoffuku ◽  
Rebecca Marquesini ◽  
Tatiane Travizan Lima ◽  
...  
Keyword(s):  
Treatment Time ◽  
Low Complexity ◽  
Class Ii ◽  
Open Bite ◽  
Class Ii Malocclusion ◽  
Anterior Open Bite ◽  
Skeletal Class ◽  
Posterior Crossbite ◽  
Skeletal Class Ii ◽  
High Predictability

Adequate planning and early treatment of Angle Class II malocclusion with maxillary atresia and anterior open bite provides harmonization of maxillomandibular bone bases in the three planes of space. Orthodontic aligners have emerged as an alternative treatment having the following advantages: being more aesthetic and more comfortable for the patient, less treatment time when they are correctly indicated, less chairside time, less complications, possibility of remote monitoring, easier feeding, and dental hygiene. On the other hand, they offer difficulties to treat adults with severe skeletal Class II malocclusions, posterior crossbite and anterior open bite. Therefore, the objective of this clinical case report is to early correct skeletal Class II malocclusion with maxillary atresia through the use of mechanical orthopedics and devices that help eliminate habits and close the anterior open bite, and later the use of orthodontic aligners to finish the treatment. It was concluded that the early interceptive treatment of malocclusion was efficient to harmonize the bone bases in the anteroposterior, vertical, and transversal directions, changing this malocclusion from high to low complexity and, consequently, highly predictable and with an excellent prognosis for treatment with orthodontic aligners. The treatment with ClearCorrect aligners corrected the occlusion in a shorter period of time when compared to corrective orthodontics and with a high predictability in relation to the virtual setup.

scholarly journals Orthodontic Treatment of Ankylosed Maxillary Incisor through Osteogenic Distraction and Simplified Biomechanics

2019 ◽  
Vol 2019 ◽  
pp. 1-10
Author(s):  
Daniel Gheur Tocolini ◽  
Priscila de Oliveira Silva ◽  
Iduilton Grabowski ◽  
Julia Carelli ◽  
Nathaly Dias Morais ◽  
...  
Keyword(s):  
Anterior Segment ◽  
Class Ii ◽  
Open Bite ◽  
Functional Improvement ◽  
Maxillary Incisor ◽  
Class Ii Malocclusion ◽  
Anterior Open Bite ◽  
Bone Segment ◽  
The Right ◽  
Dental Crowding

Ankylosed teeth may have a significant esthetic and functional impact especially at the anterior segment of the upper arch. Treatment of ankylosed teeth is challenging. The objective of this case report is to describe a clinical case in which an ankylosed tooth was treated with the use of osteogenic distraction associated with simplified orthodontic biomechanics. A 17-year-old female Caucasian patient presented with a Class II malocclusion, severe maxillary dental crowding, moderate mandibular dental crowding, anterior open bite, upper midline deviation to the right, and upper right central incisor in infraocclusion due to ankylosis. Treatment involved the use of the ankylosed tooth as anchorage for the distalization of the right upper segment to correct the Class II malocclusion and to create space prior to surgery. After one week of surgical osteotomy, traction of the tooth and bone segment was initiated with the use of intermaxillary elastics. The ankylosed tooth was moved to the desired position. Bone formation and mucogingival tissue adaptation were observed. Thus, esthetic and functional improvement was achieved. Osteogenic distraction associated with simplified orthodontic biomechanics is an alternative to the treatment of ankylosed teeth which can replace the use of distractor screws, making treatment simpler and more accessible.

Orthopedic approach in the treatment of a skeletal class II division 1 malocclusion with an anterior open bite

2005 ◽  
Vol 29 (3) ◽  
pp. 205-210
Author(s):  
N. Al-Sulaiti ◽  
G. White
Keyword(s):  
Class Ii ◽  
Open Bite ◽  
Mixed Dentition ◽  
Class Ii Malocclusion ◽  
Facial Bones ◽  
Anterior Open Bite ◽  
Correct Position ◽  
Skeletal Class ◽  
Skeletal Class Ii ◽  
Division 1

The patient presented with it skeletal class II malocclusion characterized by an anterior open bite and maxillary midline deviation. This mixed dentition case was treated orthopedically with MRI appliance to rotate and impact the maxilla. A Bionator was used advance the mandible. The case was completed using Occlus-O-Guide. The result showed that the facial bones and teeth appear in the correct position.

scholarly journals Diffuse gingival enlargement with stromal calcifications occurring in a background of amelogenesis imperfecta - An oral medicine case book

2020 ◽  
Vol 75 (8) ◽  
pp. 450-453
Author(s):  
Eric Heyl ◽  
Liam Robinson ◽  
Leande Kotze ◽  
Willie FP Van Heerden
Keyword(s):  
Open Bite ◽  
Amelogenesis Imperfecta ◽  
Radiographic Examination ◽  
Enamel Hypoplasia ◽  
Oral Medicine ◽  
Anterior Open Bite ◽  
Gingival Enlargement ◽  
Gingival Fibromatosis ◽  
Clinical Differential Diagnosis ◽  
Maxilla And Mandible

A 12-year-old female patient presented with diffusely enlarged fibrous gingivae, enamel hypoplasia, an anterior open bite and impacted permanent maxillary canines (Figures 1-4). The patient's mother reported that the child had an unremarkable medical history and was currently not taking any medications. Radiographic examination showed features of amelogenesis imperfecta affecting all erupted teeth and the impacted permanent maxillary canines (Figure 4). The clinical differential diagnosis included hereditary gingival fibromatosis or diffuse peripheral odontogenic fibromas involving both the maxilla and mandible. Gin-givectomies from the anterior maxillary and mandibular regions were performed and submitted for histological assessment.

scholarly journals Angle Class II malocclusion treated with extraction of permanent teeth

2013 ◽  
Vol 18 (4) ◽  
pp. 126-133
Author(s):  
Gustavo Mattos Barreto
Keyword(s):  
Present Report ◽  
Treatment Decision ◽  
Class Ii ◽  
Open Bite ◽  
Permanent Teeth ◽  
Class Ii Malocclusion ◽  
Anterior Open Bite ◽  
Angle Class Ii ◽  
Angle Class ◽  
Facial Esthetics

Angle Class II malocclusion associated with anterior open bite in adult patients demands a carefully elaborated orthodontic planning, aiming at restoring not only harmonious dental and facial esthetics, but also a balanced masticatory function. Orthognathic surgery or permanent teeth extraction are often the choice of treatment, therefore, treatment decision is related to all dental, skeletal and functional aspects. The present report discusses orthodontic compensation carried out by means of upper premolar extraction performed to correct the Class II canine relationship and, consequently, the anterior open bite, accepting that the upper incisors be retroclined. This clinical case was presented to the Brazilian Board of Orthodontics and Dentofacial Orthopedics (BBO) as part of the requirements for obtaining the BBO Certification.

scholarly journals Dynamic MRI Evaluation of Tongue Posture and Deglutitive Movements in a Surgically Corrected Open Bite

2006 ◽  
Vol 76 (6) ◽  
pp. 1057-1065 ◽  
Author(s):  
Seniz Karacay ◽  
Erol Akin ◽  
Kerim Ortakoglu ◽  
A. Osman Bengi
Keyword(s):  
Dynamic Mri ◽  
Class Ii ◽  
Open Bite ◽  
Class Ii Malocclusion ◽  
Anterior Open Bite ◽  
Posterior Portion ◽  
Upward Direction ◽  
Magnetic Resonance Imaging Mri ◽  
Skeletal Open Bite ◽  
Tongue Thrust

Abstract Tongue thrust usually develops in the presence of anterior open bite in order to achieve anterior valve function. In the literature, tongue thrust is described both as the result and the cause of open bite. If it is an adaptation to malocclusion, then tongue posture and deglutitive tongue movements should change after treatment. In this case report, an adult who had skeletal open bite and Class II malocclusion caused by mandibular retrusion was treated surgically. The mandible was advanced in a forward and upward direction with a sagittal split osteotomy. The open bite and Class II malocclusion were corrected and an increase in the posterior airway space (PAS) was observed. Pretreatment and posttreatment dynamic magnetic resonance imaging (MRI) revealed that tongue tip was retruded behind the incisors and contact of the tongue with the palate increased. It was also determined that the anterior and middle portions descended, whereas the posterior portion was elevated at all stages. Advancement of the mandible, correction of open bite, and an increase in PAS affected not only the tongue posture and deglutitive movements, but also the breathing pattern of the patient.

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