scholarly journals Adipokine status in patients with stable ischemic heart disease associated with affective disorders

2018 ◽  
Vol 9 (3) ◽  
pp. 54-59
Author(s):  
N. P. Dorofeeva ◽  
A. O. Ter-Akopyan ◽  
Yu. N. Оrekhova ◽  
D. N. Ivanchenko ◽  
S. V. Shlyk ◽  
...  
Keyword(s):  
Heart Disease ◽  
Depressive Symptoms ◽  
Coronary Artery ◽  
Ischemic Heart Disease ◽  
Blood Plasma ◽  
Affective Disorders ◽  
Stable Coronary Artery Disease ◽  
Ischemic Heart ◽  
Stable Ischemic Heart Disease ◽  
Artery Disease

One of the factors negatively affecting the cardiac prognosis of coronary heart disease (CHD) is affective disorders of the depressive spectrum. Symptoms of depression may increase the level of systemic inflammation and promote disorders of carbohydrate metabolism by altering the synthesis and secretion of adipokines: leptin, resistin, adiponectin. The aim of this study was to assess the adipokin status in patients with stable coronary artery disease in the conditions of conservative therapy and during percutaneous coronary interventions (PCI) with stenting, including patients with depressive symptoms. The presence of depressive symptoms was accompanied by an increase in the level of resistin in the blood plasma in patients with stable ischemic heart disease. PCI with coronary artery stenting resulted in an increase in the concentration of all the adipokines: adiponectin, leptin, resistin. Stenting of coronary arteries in people with depressive symptoms led to an increase in the level of resistin, adiponectin with a decrease in the concentration of leptin in the blood plasma on the third day after the operative intervention.

Plasma YKL-40 in relation to the degree of coronary artery disease in patients with stable ischemic heart disease

2011 ◽  
Vol 71 (5) ◽  
pp. 439-447 ◽  
Author(s):  
Anders B. Mathiasen ◽  
Marina J. Harutyunyan ◽  
Erik Jørgensen ◽  
Steffen Helqvist ◽  
Rasmus Ripa ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Heart Disease ◽  
Coronary Artery ◽  
Ischemic Heart Disease ◽  
Ischemic Heart ◽  
Stable Ischemic Heart Disease ◽  
Artery Disease

scholarly journals Management of stable coronary artery disease: from evidence to clinical practice

2017 ◽  
Vol 11 (2) ◽  
pp. 114 ◽  
Author(s):  
Riccardo Gerloni ◽  
Luciano Mucci ◽  
Tiziana Ciarambino ◽  
Manuel Ventura ◽  
Valeria Baglio ◽  
...  
Keyword(s):  
Heart Disease ◽  
Coronary Artery ◽  
Ischemic Heart Disease ◽  
Stable Coronary Artery Disease ◽  
Coronary Intervention ◽  
Ischemic Heart ◽  
Cardiac Syndrome ◽  
Percutaneous Coronary ◽  
Artery Disease

Ischemic heart disease, the leading cause of death, is extremely diffuse among patients hospitalized in Internal Medicine ward so that Internist should be able to manage correctly this disease. The following review revises the most recent literature and offers a practical clinical guide to be confident on this topic. After having emphasized that clinical overview remains essential, it briefly mentions advantages and limits of different investigations, reminds readers of possible alternative etiopathogeneses of ischemic heart disease (cardiac syndrome X), reports the most appropriate medical therapy, and gives the opportunity to understand appropriateness of specialist strategies such as coronary artery by-pass grafting and percutaneous coronary intervention. Finally, it illustrates a rational and evidence-based follow-up of these patients, considering that only a small part of them should be followed by a Cardiologist. The aim of a correct management of ischemic heart disease remains to reduce mortality and improve the quality of life.

scholarly journals Value of Cardiogoniometry in Diagnosis of Coronary Artery Disease in Patients with Suspected Stable Ischemic Heart Disease

2019 ◽  
Vol 60 (3) ◽  
pp. 527-538 ◽  
Author(s):  
Alireza Sepehri Shamloo ◽  
Boris Dinov ◽  
Livio Bertagnolli ◽  
Philipp Sommer ◽  
Daniela Husser-Bollmann ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Heart Disease ◽  
Coronary Artery ◽  
Ischemic Heart Disease ◽  
Ischemic Heart ◽  
Stable Ischemic Heart Disease ◽  
Artery Disease

scholarly journals PLASMA YKL-40 IN RELATION TO THE DEGREE OF CORONARY ARTERY DISEASE IN PATIENTS WITH STABLE ISCHEMIC HEART DISEASE

2011 ◽  
Vol 57 (14) ◽  
pp. E1149 ◽  
Author(s):  
Anders B. Mathiasen ◽  
Marina J. Harutyunyan ◽  
Erik Jørgensen ◽  
Steffen Helqvist ◽  
Rasmus Ripa ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Heart Disease ◽  
Coronary Artery ◽  
Ischemic Heart Disease ◽  
Ischemic Heart ◽  
Stable Ischemic Heart Disease ◽  
Artery Disease

Gender Differences in Non-Obstructive Coronary Artery Disease

2020 ◽  
Vol 26 ◽  
Author(s):  
Maria Bergami ◽  
Marialuisa Scarpone ◽  
Edina Cenko ◽  
Elisa Varotti ◽  
Peter Louis Amaduzzi ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Gender Differences ◽  
Heart Disease ◽  
Coronary Artery ◽  
Ischemic Heart Disease ◽  
Coronary Arteries ◽  
Obstructive Coronary Artery Disease ◽  
Ischemic Heart ◽  
Current Evidence ◽  
Artery Disease

: Subjects affected by ischemic heart disease with non-obstructive coronary arteries constitute a population that has received increasing attention over the past two decades. Since the first studies with coronary angiography, female patients have been reported to have non-obstructive coronary artery disease more frequently than their male counterparts, both in stable and acute clinical settings. Although traditionally considered a relatively infrequent and low-risk form of myocardial ischemia, its impact on clinical practice is undeniable, especially when it comes to infarction, where the prognosis is not as benign as previously assumed. Unfortunately, despite increasing awareness, there are still several questions left unanswered regarding diagnosis, risk stratification and treatment. The purpose of this review is to provide a state of the art and an update on current evidence available on gender differences in clinical characteristics, management and prognosis of ischemic heart disease with non-obstructive coronary arteries, both in the acute and stable clinical setting.

Abstract 342: Impact Of System And Physician Factors On The Diagnostic Yield Of Coronary Angiography In Stable Ischemic Heart Disease: A Population Based Study

2014 ◽  
Vol 7 (suppl_1) ◽  
Author(s):  
Harindra C Wijeysundera ◽  
Feng Qiu ◽  
Maria C Bennell ◽  
Madhu K Natarajan ◽  
Warren J Cantor ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Heart Disease ◽  
Coronary Artery ◽  
Coronary Angiography ◽  
Ischemic Heart Disease ◽  
Diagnostic Yield ◽  
Obstructive Coronary Artery Disease ◽  
Ischemic Heart ◽  
Patient Factors ◽  
Artery Disease

Background: Wide variation exists in the diagnostic yield of coronary angiography in stable ischemic heart disease (IHD). Previous work has primarily focused on patient factors for this variation. We sought to understand if system and physician factors, specifically hospital and physician type, as well as physician self-referral, have incremental impacts on the yield of coronary angiography, above and beyond that of patient factors alone. Methods: All patients who underwent a diagnostic coronary angiogram for possible stable IHD, at the 18 cardiac centers in Ontario, Canada were identified from October 1st, 2008 to September 30th, 2011. Obstructive coronary artery disease was defined as stenosis greater than 70% in the main coronary arteries or greater than 50% in the left main artery. Physicians were classified as either invasive or interventional. Hospitals were categorized into cath only, stand-alone PCI and full service centers. Multi-variable hierarchical logistic models were developed to identify system and physician level predictors of obstructive coronary artery disease, having adjusted for patient factors. Results: Our cohort consisted of 60,986 patients who underwent a diagnostic angiogram for possible stable IHD, of which 33,483 had obstructive coronary artery disease (54.9%), ranging from 41.0% to 70.2% across centers. Self-referral rates varied from 4.8% to 74.6%. Fewer self-referral patients (52.5%) had obstructive coronary artery disease compared to non-self-referral patients (56.5%), with an odds ratio (OR) of 0.89 (95% CI 0.85-0.93;p <0.001), after accounting for patient factors. Angiograms performed by interventional physicians had a higher likelihood of showing obstructive coronary artery disease (60.1% vs. 50.8%; OR 1.22; 95% CI 1.17-1.28; p<0.001). Fewer angiograms at cath only centers showed obstructive disease (45.0%) compared to full service centers (58.1%); this was of borderline significance (OR 0.59; 95% CI 0.34-1.00; p=0.05). Conclusion: Physician and system factors are important predictors of the diagnostic yield of coronary angiography in stable IHD, even after accounting for patient characteristics. Further study into the drivers of how these physician and system factors impact diagnostic yield is an important focus for quality improvement.

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