Clinical Practice
Latest Publications


TOTAL DOCUMENTS

516
(FIVE YEARS 284)

H-INDEX

4
(FIVE YEARS 3)

Published By Eco-Vector

2220-3095
Updated Saturday, 27 November 2021

2021 ◽  
Author(s):  
Dmitry Skvortsov ◽  
Sergey Kaurkin ◽  
Galina Ivanova ◽  
Boris Poliaev ◽  
Maria Bulatova

Yes


2021 ◽  
Author(s):  
Vitaliy E. Potapov ◽  
Vladimir Alekseevich Sorokovikov ◽  
Sergey Nikolaevich Larionov ◽  
Aleksandr Petrovich Zhivotenko

The problem of the pathology of the facet joints of the lumbar spine remains significant and is medical and social due to persistent pain syndrome, high incidence of morbidity and frequent disability outcomes. The complex anatomical and topographic relationships of the facet joints, intervertebral discs and radicular nerves force clinicians to pay attention to the pathology of facet syndrome. A pair of facet joints and an intervertebral disc constitute a functional unit - a "three-component complex" and are interconnected with each other. The article examines the anatomical and morphological features and radiological classifications of degenerative changes in the facet joints, which are currently used in clinical practice. Facet joint pathologies are the most common nosological form of degenerative-dystrophic process (spondyloarthrosis) and a potential source of pain with the formation of instability of the spinal motion segment and the formation of chronic pain syndrome. The features of facet syndrome diagnostics are presented on a clinical example of surgical treatment by means of laser dereception of facet joints.


2021 ◽  
Vol 3 (2) ◽  
pp. 20-25
Author(s):  
Anna G. Sotnikova ◽  
Alexander V. Averyanov ◽  
Tamara A. Turusina ◽  
Victor N. Lesnyak ◽  
Dmitry V. Sazonov ◽  
...  

The case of a rare lung disease - alveolar proteinosis diagnosed with advanced technologies, including confocal laser endomicroscopy of respiratory tract (alveoscopy) is presented. After confirming the diagnosis the patient undewent high volume bronchoalveolar lavage of both lungs with positive clinical and radiologic dynamics.


2021 ◽  
Vol 3 (2) ◽  
pp. 40-47
Author(s):  
Arnold V. Popkov ◽  
Dmitriy A. Popkov ◽  
Konstantin V. Trofimov ◽  
Alexander I. Nikiforov ◽  
Alexey А. Isupov

The study concerns a new method of treatment of bone fractures of upper and lower limbs based on osteogenesis stimulation by intramedullary implants with bioactive organic hydroxyapatite (HA). The method decreases consolidation period of diaphyseal fractures to 2-4 times. A technology of osteosynthesis and bone formation dynamics at the fracture zone and around the implant is described.


2021 ◽  
Vol 3 (2) ◽  
pp. 4-12
Author(s):  
Alexandr V. Averyanov ◽  
Anatolyi G. Konoplyannikov ◽  
Fedor G. Zabozlaev ◽  
Anastasyi S. Sorokina ◽  
Dmitryi A. Akulshin ◽  
...  

In the last years several studies have shown that mesenchymal stem cells (MSCs) are able to reduce the systemic inflammatory response and mortality in experimental models of sepsis. As recently found, the surface of MSCs have receptors for erythropoietin (EPO). So we hypothesized that the introduction of EPO together with MSCs may enhance their effect and improve the results of sepsis treatment. Aim: То evaluate morphologic and immunologic effects of combined treatment with EPO and MSC in an experimental LPS sepsis model in rats. Methods: 50 Wistar rats were randomized into 5 groups: Group 1 - the healthy controls, Groups 2-5 were intraperitoneally introduced bacterial LPS 20 mg/kg. Two hours after LPS injection animals received the following intravenous treatments: Group 3 - 4xl05 allogeneic MSCs, Group 4 - 8.5 pg of recombinant EPO-beta, Group 5 - MSCs and EPO in the same doses. Surviving animals were euthanased on the 4th day. The morphological study of the liver, spleen, thymus, lungs, kidney tissues was performed. We analyzed the tissue changes, white blood cells count and serum level of IL-l, IL-2, IL-6, TNF-. Results: Mortality in LPS groups did not differ. The highest white blood cells count was found in the group of combined treatment EPO+MSCs (8.15x106 cells/ml) compared with controls (2,15x10s cells/ml) and LPS controls (6,52x10s cells/ml). There were no differences in levels of TNF-, IL-2 and IL-6 between the groups, but serum IL-1 level in groups 2 and 4 was significantly higher than in treated with MSCs and MSCc + EPO animals. Histologically in the group 5 we observed significantly less leukocyte lung interalveolar septal infiltration and kidney tubular dystrophy. The most significant differences in group LPS + EPO were found in the lymphoid tissue - considerable hyperplasia of spleen white pulp and thymus cortex, whereas in the other groups different degrees of atrophy of the corresponding zones were noted. Conclusions: Combined treatment with EPO and MSCs can reduce acute lung injury and kidney damage, cause hyperplasia of lymphoid tissue and enhance the immune response more than separate treatment in an experimental model of sepsis in rats.


2021 ◽  
Vol 3 (2) ◽  
pp. 48-50
Author(s):  
Alexee V. Baranov ◽  
Dmitriy N. Panchenkov ◽  
Marina E. Behteva ◽  
Basil N. Shirshov

We describe the first clinical experience of laparoscopic surgery for renal cyst by a single access. Advantages, disadvantages and prospects of this method are analized.


2021 ◽  
Vol 3 (2) ◽  
pp. 58-70
Author(s):  
Oleg B. Kerbikov ◽  
Alexander V. Averyanov ◽  
Ekaterina N. Borskaya ◽  
Tamara V. Krutova

The review is dedicated to the use of the cardiopulmonary exercise testing (CPET) in clinical practice. Main modes of CPET, most popular protocols and testing methods are discussed in details. Ample space is dedicated to main parameters measuring during CPET, their physiological values and changes in different pathological states. Main indications for CPET are presented and special attention is given to the use of CPET in chronic heart failure, apnea, lung diseases, skeletal muscle fiber and mitochondrial myopathy, rehabilitation. Emerging applications of CPET like congenital heart disease, pulmonary resection and several other are also discussed.


2021 ◽  
Vol 3 (2) ◽  
pp. 26-30
Author(s):  
Yuryi V. Ivanov ◽  
Fedor G. Zabozlaev

The clinical case of the patient with squamous cell carcinoma of gall bladder in a combination with cholelithic illness is described. Presurgical diagnostics of gall bladder cancer is difficult, demands a complex and careful assessment of disease anamnesis, a clinical sings, results of laboratory and tool analysis. At impossibility to exclude gall bladder cancer in the presence of a cholelithic illness in all cases operative treatment is needed.


2021 ◽  
Vol 3 (2) ◽  
pp. 51-57
Author(s):  
Igor V. Molchanov ◽  
Nikolay E. Burov ◽  
Natalia N. Pulina ◽  
Oleg N. Cherkavsky

The description of intubation problem, its causes, possibilities and predictions is given. The estimation scale can be also seen in the article. As well as the actions of the doctor in case of the intubation and different technical processes for prevention of the fatal case.


2021 ◽  
Vol 3 (2) ◽  
pp. 71-80
Author(s):  
Margarita E. Semendyaeva

The article considers the non-alcoholic fatty liver disease as an important medical and social problem. This problem include such questions as metabolic syndrome, essential lipoproteinemia, insulinoresistance. It is possible to consider non-alcoholic steatohepatitis as predictor of liver fibrosis and chirrosis. The questions of diagnosis and treatment are discussed.


Sign in / Sign up

Export Citation Format

Share Document