scholarly journals Molecular-genetic characterization of the human non-hypervariable GC-rich minisatellite UPS29 of gene CENTB5

2007 ◽  
Vol 5 (3) ◽  
pp. 35-45 ◽  
Author(s):  
Irina O Suchkova ◽  
Daria M Shubina ◽  
Ludmila K Sasina ◽  
Natalia O Slominska ◽  
Vadim B Vasilyev ◽  
...  
Keyword(s):  
Genetic Analysis ◽  
In Silico ◽  
Genetic Characterization ◽  
Molecular Genetic ◽  
Molecular Genetic Analysis ◽  
First Time ◽  
Molecular Genetic Characterization

Human minisatellite UPS29 localized in one of CENTB5 introns was studied in silico and using molecular genetic analysis. For the first time there were revealed seven UPS29 alleles which contained 6-24 repeated units. Allele consisting of 17 repeats was prevailed (91,5 %). Frequency of other alleles varied from 0,29 % to 4,39 %. UPS29 heterozygosity was 12,3 %. Minisatellite UPS29 was classified as low polymorphic and non hypervariable.

scholarly journals Metabolic Flux in Both the Purine Mononucleotide and Histidine Biosynthetic Pathways Can Influence Synthesis of the Hydroxymethyl Pyrimidine Moiety of Thiamine in Salmonella enterica

2002 ◽  
Vol 184 (22) ◽  
pp. 6130-6137 ◽  
Author(s):  
Shara Allen ◽  
Julie L. Zilles ◽  
Diana M. Downs
Keyword(s):  
Metabolic Flux ◽  
Genetic Characterization ◽  
Molecular Genetic ◽  
Thiamine Pyrophosphate ◽  
Wild Type ◽  
Regulatory Pathway ◽  
Informational Suppressors ◽  
Pyrimidine Moiety ◽  
Molecular Genetic Characterization

ABSTRACT Together, the biosyntheses of histidine, purines, and thiamine pyrophosphate (TPP) contain examples of convergent, divergent, and regulatory pathway integration. Mutations in two purine biosynthetic genes (purI and purH) affect TPP biosynthesis due to flux through the purine and histidine pathways. The molecular genetic characterization of purI mutants and their respective pseudorevertants resulted in the conclusion that <1% of the wild-type activity of the PurI enzyme was sufficient for thiamine but not for purine synthesis. The respective pseudorevertants were found to be informational suppressors. In addition, it was shown that accumulation of the purine intermediate aminoimidazole carboxamide ribotide inhibits thiamine synthesis, specifically affecting the conversion of aminoimidazole ribotide to hydroxymethyl pyrimidine.

Molecular genetic characterization of rabies virus glycoprotein gene sequences from rabid dogs in Bangkok and neighboring provinces in Thailand, 2013–2014

2016 ◽  
Vol 161 (5) ◽  
pp. 1261-1271 ◽  
Author(s):  
Surachet Benjathummarak ◽  
Chanon Fa-ngoen ◽  
Chonlatip Pipattanaboon ◽  
Khwanchit Boonha ◽  
Pongrama Ramasoota ◽  
...  
Keyword(s):  
Rabies Virus ◽  
Genetic Characterization ◽  
Molecular Genetic ◽  
Gene Sequences ◽  
Rabies Virus Glycoprotein ◽  
Virus Glycoprotein ◽  
Glycoprotein Gene ◽  
Molecular Genetic Characterization

Molecular genetic characterization of the Lr34/Yr18 slow rusting resistance gene region in wheat

2006 ◽  
Vol 114 (1) ◽  
pp. 21-30 ◽  
Author(s):  
E. S. Lagudah ◽  
H. McFadden ◽  
R. P. Singh ◽  
J. Huerta-Espino ◽  
H. S. Bariana ◽  
...  
Keyword(s):  
Resistance Gene ◽  
Genetic Characterization ◽  
Molecular Genetic ◽  
Gene Region ◽  
Slow Rusting ◽  
Molecular Genetic Characterization

Molecular Genetic Characterization of Two Insular Asian Cat Species, Bornean Bay Cat and Iriomote Cat

1999 ◽  
pp. 223-248 ◽  
Author(s):  
Warren E. Johnson ◽  
Fumiharu Shinyashiki ◽  
Marilyn Menotti Raymond ◽  
Carlos Driscoll ◽  
Charles Leh ◽  
...  
Keyword(s):  
Genetic Characterization ◽  
Molecular Genetic ◽  
Molecular Genetic Characterization

scholarly journals Molecular genetic characterization of myeloid/lymphoid neoplasms associated with eosinophilia and rearrangement of PDGFRA, PDGFRB, FGFR1 or PCM1-JAK2

Haematologica ◽  
2018 ◽  
Vol 103 (8) ◽  
pp. e348-e350 ◽  
Author(s):  
Constance Baer ◽  
Verena Muehlbacher ◽  
Wolfgang Kern ◽  
Claudia Haferlach ◽  
Torsten Haferlach
Keyword(s):  
Genetic Characterization ◽  
Molecular Genetic ◽  
Lymphoid Neoplasms ◽  
Molecular Genetic Characterization
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