Persistent dysuria in women: etiological diagnostics and treatment

INTRODUCTION:Dysuria is a painful urination combined with its frequency and/or difficulty. Dysuria is observed in many urological diseases and is one of the most common reasons for treatment for urological cause. AIM:The aim of the study is to identify the etiological factors of dysuria in women and to evaluate a personalized approach to their treatment. MATERIALS AND METHODS:We analyzed the data of 368 women with chronical cystitis. The inclusion criteria for the study were the presence of dysuria (painful and frequent urination more than 8 times a day with or without difficulty), the prescription of urination disorders over one year old and age 18 and over. All patients underwent a comprehensive urological examination to identify the causes of urinary disorders. RESULTS:The Bacterial cystitis was confirmed only in 78 (21.2%) patients among all 368 women. In the remaining 290 (78.8%) patients, the causes of persistent dysuria were other diseases: bladder leukoplakia in 154 (41.8%), bladder pain syndrome/interstitial cystitis in 38 (10.3%), viral cystitis in 34 (9.3%), paraurethral formations in 29 (7.9%), neurogenic urinary dysfunction bladder in 25 (6.8%), urethral pain syndrome in 5 (1.4%) patients. Dysuria was also caused by postradiation cystitis (2 patients), secondary stones in the urinary bladder (2 patients), and one patient had extragenital endometriosis. CONCLUSIONS:The variety of reasons for the development of persistent dysuria in women requires careful examination of patients. Treatment should be carried out only after accurate verification of the diagnosis.

Download Full-text

Depression and helplessness impact interstitial cystitis/bladder pain syndrome pain over time

Canadian Urological Association Journal ◽

10.5489/cuaj.5703 ◽

2018 ◽

Vol 13 (10) ◽

pp. 328-33 ◽

Cited By ~ 1

Author(s):

Alison Crawford ◽

Dean A. Tripp ◽

J. Curtis Nickel ◽

Lesley Carr ◽

Robert Moldwin ◽

...

Keyword(s):

Emotion Regulation ◽

Interstitial Cystitis ◽

Symptom Management ◽

Pain Catastrophizing ◽

Tertiary Care ◽

Pain Syndrome ◽

Bladder Pain Syndrome ◽

Unknown Etiology ◽

Bladder Pain ◽

One Year

Introduction: Interstitial cystitis/bladder pain syndrome (IC/BPS) is a devastating urological chronic pelvic pain condition with an unknown etiology. Evidence-based psychological strategies are becoming more successful for symptom management as we learn more about the targets for intervention. Previous research has established an indirect relationship between depression and pain through catastrophizing, but there have yet to be studies examining the emerging role of emotion regulation in this relationship. Methods: Women with IC/BPS were recruited from tertiary care clinics in Canada and the U.S. between 2013 and 2018. Patients completed questionnaires, including demographics and scores for pain, depression, catastrophizing, and difficulties in emotion regulation at baseline, six months, and one year. Serial mediation was used to test models of pain, catastrophizing, and depression. Results: A total of 135 women with IC/BPS completed all three time points. The only significant indirect path was from baseline depression to catastrophizing at six months to pain at one year (b=0.10; confidence interval [CI] 0.0049–0.2520). A followup analysis demonstrated that helplessness was the key factor of catastrophizing driving this relationship (b=0.17; CI 0.0282–0.3826). Conclusions: Reducing feelings of helplessness and increasing patient feelings of control are important ways to limit the effect of low mood on patient pain experience. De-catastrophizing interventions should be part of the referral strategy for IC/BPS symptom management.

Download Full-text

Is Urethral Pain Syndrome Really Part of Bladder Pain Syndrome?

Urogenital Tract Infection ◽

10.14777/uti.2017.12.1.22 ◽

2017 ◽

Vol 12 (1) ◽

pp. 22 ◽

Cited By ~ 2

Author(s):

Sung Tae Cho

Keyword(s):

Pain Syndrome ◽

Bladder Pain Syndrome ◽

Bladder Pain ◽

Urethral Pain

Download Full-text

The chicken or the egg: Longitudinal changes in pain and catastrophizing in women with interstitial cystitis/bladder pain syndrome

Canadian Urological Association Journal ◽

10.5489/cuaj.7106 ◽

2021 ◽

Vol 15 (10) ◽

Author(s):

Alison Crawford ◽

Abi Muere ◽

Dean A. Tripp ◽

J. Curtis Nickel ◽

R. Christopher Doiron ◽

...

Keyword(s):

Interstitial Cystitis ◽

Pelvic Pain ◽

Psychological Treatment ◽

Pain Catastrophizing ◽

Tertiary Care ◽

Pain Syndrome ◽

Bladder Pain Syndrome ◽

Future Research ◽

Bladder Pain ◽

One Year

Introduction: Evidence-based psychological strategies are being used as clinicians look for helpful interventions for patients diagnosed with the enigmatic chronic urological pelvic pain condition of interstitial cystitis/bladder pain syndrome (IC/BPS). Pain and pain catastrophizing are associated with chronic pelvic pain outcomes but the longitudinal role of catastrophizing on patient pain in IC/BPS remains unknown. Methods: Women with IC/BPS were recruited from tertiary care clinics across North America and completed a battery of questionnaires, including demographics, pain, depression, catastrophizing at baseline, six months, and one year. Results: A total of 226 patients completed baseline, 183 completed the six-month survey, and 151 completed the one-year survey. Using a cross-lagged analysis, early changes in pain catastrophizing predicted later changes in pain, but not vice versa. Followup subscale analyses revealed that early changes in magnification predicted later changes in pain, early changes in pain predicted later changes in rumination, and that there was a recursive relationship between changes in helplessness and changes in pain across the study. Conclusions: Pain catastrophizing should be considered a prime target in psychological treatment for chronic pain in patients with IC/BPS, particularly those thinking styles associated with pain onset and maintenance. Future research should be conducted with constructs such as pain catastrophizing in samples prioritizing diversity of patients with IC/BPS and mechanisms as to how to effectively decrease catastrophizing.

Download Full-text