2013 ◽  
Vol 128 (2_suppl) ◽  
pp. 20-33 ◽  
Author(s):  
John C. Ridderhof ◽  
Anthony D. Moulton ◽  
Renée M. Ned ◽  
Janet K.A. Nicholson ◽  
May C. Chu ◽  
...  

2015 ◽  
Vol 5 (4) ◽  
pp. 289-292 ◽  
Author(s):  
Samita Adhikari ◽  
Biswas Neupane ◽  
Komal Raj Rijal ◽  
Megha Raj Banjara ◽  
Bishnu Prasad Uphadhaya ◽  
...  

2020 ◽  
Vol 8 (3) ◽  
pp. 100-104
Author(s):  
Goris BMT

The human T-cell lymphotropic virus types 1 and 2 (HTLV 1/2) are well known causes of adult T cell leukemia lymphoma. Both viruses were established to be transmitted through various mode including sexual contact and blood transfusion. This study was aimed to determine the seroprevalence of HTLV-1/2 antibodies among blood donors in Public Health Laboratory. During the period of August 2019 to October 2019 a total of 394 blood samples were obtained from blood donors visiting the Blood bank of National Public Health Laboratory, both males and females were included. The blood samples were analyzed for the presence of anti - HTLV-1,2 by a commercially available enzyme-linked immune-sorbent assay following the instructions of the manufacturer. The study participants were included 361 (91.6%) males and 33 (8.4%) females. The result show that of the 394 blood donors, four (4) were found to be seropositive for HTLV-1 antibodies giving a prevalence of 1.02%. While all samples were negative for the HTLV-2 antibodies. Among HTLV-1 positive cases 3 were male (75%) while only one female (25%) was found to be seropositive for HTLV-1 antibodies. None of the married donors was found to be seropositive for HTLV-1. We conclude that the seroprevalence of HTLV 1/2 were matched to the internationally estimated prevalence among blood donors at Blood Bank of national health laboratory and the majority of the cases were male under 40 years old. Further studies should be done with inclusion of more samples and using more sensitive technique like Western blot or PCR.


2019 ◽  
Vol 134 (2_suppl) ◽  
pp. 37S-42S ◽  
Author(s):  
David Mills ◽  
Sherrie Staley ◽  
Steven Aisu ◽  
Twila Kunde ◽  
Paul Kimsey ◽  
...  

International initiatives to strengthen national health laboratory systems in resource-poor countries are often hampered by unfamiliarity with the country’s health laboratory environment and turnover of international partners during the initiative. This study provides an overview of, and lessons learned from, the use of a laboratory long-term partnership approach (ie, “twinning”) to strengthen the national public health laboratory system in an international setting. We focused on the partnering of the Uganda Ministry of Health Central Public Health Laboratory (CPHL) with the New Mexico State Public Health Laboratory to help the CPHL become Uganda’s national public health reference laboratory (Uganda National Health Laboratory Services [UNHLS] Institute) and leader of its nascent Uganda National Health Laboratory Network (UNHLN). Via twinning, CPHL leadership received training on laboratory leadership and management, quality systems, facility management, and the One Health environmental strategy (ie, that the health of persons is connected to the health of animals and the environment), and drafted a National Health Laboratory Policy, UNHLS Institute business plan, and strategic and operating plans for the UNHLS Institute and UNHLN. The CPHL is now responsible for the UNHLS Institute and coordinates the UNHLN. Lessons learned include (1) twinning establishes stable long-term collaborations and (2) success requires commitment to a formal statement of activities and objectives, as well as clear and regular communication among partners.


2017 ◽  
Vol 97 (4_Suppl) ◽  
pp. 21-27 ◽  
Author(s):  
Frantz Jean Louis ◽  
Josiane Buteau ◽  
Jacques Boncy ◽  
Renette Anselme ◽  
Magalie Stanislas ◽  
...  

2017 ◽  
Vol 9 (12) ◽  
pp. 233-236
Author(s):  
Shakya Geeta ◽  
Kumar Mahto Raj ◽  
Khadka Sundar ◽  
Dhital Subhash ◽  
Bahadur Baniya Jagat ◽  
...  

2015 ◽  
Vol 15 (2) ◽  
pp. 85-90
Author(s):  
Binit Lamichhane ◽  
Binita Pudasaini ◽  
Bishnu Upadhyay ◽  
Mohan Sharma ◽  
Shyam Prasad Khanal

The primary infection of Toxoplasma gondii, Rubella virus, Cytomegalovirus (CMV) and Herpes simplex virus (HSV) abbreviated as TORCH, remain a major problem in the women of child bearing age in Nepal. The main aim of this study was to determine the seroprevalence of TORCH infections among the women of child bearing age visiting the National Public Health Laboratory (NPHL), Kathmandu. Serum samples collected from 302 patients were tested for TORCH infections by IgM Enzyme Linked Immunosorbent Assay (ELISA). The seropositivity rate was found to be 18.82% (54/287) for T. gondii, 10.07% (28/278) for Rubella, 16.49% (46/279) for CMV and 23.34% (67/287) for HSV. The seropositivity rates in pregnant women were 17.92% (19/106) for T. gondii, 11.54% (12/104) for Rubella, 19.23% (20/104) for CMV and 25% (26/104) for HSV, the statistical association of TORCH infections with pregnancy was insignificant (P>0.05). Similarly, the seropositivity rates in women with bad obstetric history (BOH) were 17.84% (43/241) for T. gondii, 11.06% (26/235) for Rubella, 18.57% (44/237) for CMV and 26.14% (63/241) for HSV. The statistical association of CMV and HSV with previous obstetric performance were significant (P>0.05) while that of T. gondii and Rubella were insignificant (P<0.05). The seropositivity rate was found to be highest for HSV infection (23.34%) followed by T. gondii (18.82%), Cytomegalovirus (16.49%) and Rubella (10.07%).DOI: http://dx.doi.org/njst.v15i2.12120Nepal Journal of Science and Technology Vol. 15, No.2 (2014) 85-90


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