Cushing’s Disease – Quality of Life, Recurrence and Long-term Morbidity
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Cushing’s disease (CD) is a rare disorder caused by an adrenocorticotropic hormone (ACTH)-secreting pituitary adenoma. Chronic exposure to hypercortisolism leads to significant morbidities, which may be only partially reversible after remission of the disease, as well as to impairment of the health-related quality of life (HRQoL) and an increase in mortality. Transsphenoidal surgery (TSS) is the treatment of choice, and recurrence rates vary widely, confirming the need for lifelong follow-up. This review summarises the studies performed on HRQoL, recurrence rates and morbidities in patients who have CD.
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2021 ◽
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1991 ◽
Vol 9
(1)
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pp. 47-52
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2012 ◽
Vol 34
(23)
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pp. 1971-1977
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