scholarly journals Renal Cell Carcinoma with Rhabdoid Features: Report of a Rare Case Diagnosed on Endobronchial Ultrasound-Guided Fine Needle Aspiration

2015 ◽  
Vol 2 (1) ◽  
Author(s):  
Wei Xie
2015 ◽  
Vol 2 (2) ◽  
pp. 70-74
Author(s):  
Yaseen Alastal ◽  
Tariq A Hammad ◽  
Ehsan Rafiq ◽  
Mohamad Nawras ◽  
Osama Alaradi ◽  
...  

Endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) biopsy sampling of enlarged lymph nodes is increasingly used to diagnose metastatic tumors, especially of the gastrointestinal tract and the lungs. Herein, we describe the diagnosis of metastatic renal cell carcinoma from a native kidney of a 54 year-old male patient, who had a 5-years history of renal transplant, by EUS-FNA of mediastinal and celiac lymph nodes. Histological and immunohistochemical findings confirmed the origin of metastatic tumor. EUS-FNA with proper cytological evaluation can be useful in the diagnosis of metastatic renal cell carcinoma in renal transplant patients. 


2016 ◽  
Vol 4 (4) ◽  
pp. 537-540 ◽  
Author(s):  
AZUSA TANIMOTO ◽  
SHINJI TAKEUCHI ◽  
HIROSHI YAEGASHI ◽  
HIROSHI KOTANI ◽  
HIDENORI KITAI ◽  
...  

CytoJournal ◽  
2016 ◽  
Vol 13 ◽  
pp. 24 ◽  
Author(s):  
Rahul Pannala ◽  
Karyn M. Hallberg-Wallace ◽  
Amber L. Smith ◽  
Aziza Nassar ◽  
Jun Zhang ◽  
...  

Introduction: The increasing use of endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) cytology to examine pancreatic neoplasms has led to an increase in the diagnosis of metastases to the pancreas. Renal cell carcinoma (RCC) is the most common metastasis to the pancreas. Our study examines 33 cases of metastatic RCC to the pancreas sampled by EUS-FNA from four large tertiary care hospitals. Materials and Methods: We searched the cytopathology database for RCC metastatic to the pancreas diagnosed by EUS-FNA from January 2005 to January 2015. Patient age, history of RCC, nephrectomy history, follow-up postnephrectomy, radiological impression, and EUS-FNA cytologic diagnosis were reviewed. Results: Thirty-three patients were identified. The average age was 67.5 years (range, 49–84 years). Thirty-two patients had a previous documented history of RCC. One patient had the diagnosis of pancreatic metastasis at the same time of the kidney biopsy. Thirty-one patients had been treated with nephrectomy. Twenty-seven patients were being monitored annually by computed tomography or magnetic resonance imaging. Twenty-five patients had multiple masses by imaging, but 8 patients had a single mass in the pancreas at the time of EUS-FNA. EUS-FNA of 20 cases showed classic morphology of RCC. Thirteen cases had either “atypical” clinical-radiologic features or morphologic overlaps with primary pancreatic neoplasms or other neoplasms. Cell blocks were made on all 13 cases and immunochemical stains confirmed the diagnosis. Conclusions: EUS-FNA cytology is useful for the diagnosis of metastatic RCC to the pancreas. Cytomorphology can be aided with patient history, imaging analyses, cell blocks, and immunochemical stains.


2007 ◽  
Vol 51 (1) ◽  
pp. 9-15 ◽  
Author(s):  
Javier Salamanca ◽  
Nuria Alberti ◽  
Fernando López-Ríos ◽  
Andrés Perez-Barrios ◽  
Miguel Angel Martínez-González ◽  
...  

2015 ◽  
Vol 59 (3) ◽  
pp. 239-247 ◽  
Author(s):  
Chung Hun Lee ◽  
Soo Young Chung ◽  
Kyung Chul Moon ◽  
In Ae Park ◽  
Yul Ri Chung ◽  
...  

Objective: Fine-needle aspiration cytology (FNAC) based on a liquid-based preparation is a safe and valuable diagnostic tool. However, due to unfamiliarity with this method and the considerably altered morphology that is associated with it, diagnosing renal cell carcinoma (RCC) from this type of preparation remains a challenge for cytopathologists. The aim of this study was to evaluate the cytomorphological characteristics of SurePath™ (SP)-based preparations compared with conventional smear (CS), and also the role of SP-based FNAC in the diagnosis of clear-cell RCC (CRCC), the most common primary renal malignancy. Study Design: Ex vivo FNAC of both tumors and normal renal parenchyma was prepared from 73 cases. Comparative cytomorphological analysis between liquid-based cytology (LBC) and CS as well as Fuhrman nuclear grading (FNG) was carried out. Immunocytochemistry was performed from normal and CRCC cytology specimens. Results: Normal renal cytology (NRC) showed no significant morphological differences between LBC and CS. For CRCC, LBC showed small, fragmented cell clusters, a 3-dimensional configuration, distinct cytoplasmic vacuoles, and irregular nuclear contours when compared with CS. FNG was overgraded with LBC compared to with CS. AMACR was the most valuable immunocytochemical marker for distinguishing CRCC from NRC. Conclusion: Once cytopathologists become familiar with the altered cytomorphological features of CRCC, FNAC, along with immunocytochemistry, may prove helpful for diagnosis.


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