This study investigated cultural factors’ contribution to degree completion among American Indian college students. Surveys were sent to 238 currently enrolled and 87 formerly enrolled American Indian students during March 2013. From the survey respondents, a group of ten, all currently enrolled American Indian students, agreed to one-on-one interview sessions with the researcher. Dialoguing sessions were recorded and transcribed; answers were analysed and subjected to close examination through metasynthesis leading to the discovery of themes. Verification of dialogue and transcriptions through triangulation was obtained. The results indicated there were no reported cultural factors that contributed to the retention or attrition of the American Indian college student. For administrators, faculty and staff, the findings affirm practices used to welcome students of various cultures may be effective in preventing attrition of the American Indian student and that cultural factors may not play a role in retention or attrition.