scholarly journals Comparative evaluation of low dose-vaginal misoprostol and intra-cervical dinoprostone for cervical ripening and induction of labour in term pregnancy

2016 ◽  
pp. 4303-4307
Author(s):  
Priyanka Sharma ◽  
Sujata Sharma ◽  
Harbhajan Shergill
Keyword(s):  
Comparative Evaluation ◽  
Low Dose ◽  
Induction Of Labour ◽  
Cervical Ripening ◽  
Term Pregnancy ◽  
Vaginal Misoprostol

scholarly journals TO COMPARE THE EFFICACY OF PGE2 GEL AND 25ΜG OF INTRAVAGINAL MISOPROSTOL FOR INDUCTION OF LABOR IN TERM PROM

2020 ◽  
Vol 4 (1) ◽  
Author(s):  
Sunita Maheshwari ◽  
Shweta Jinger
Keyword(s):  
Low Dose ◽  
Induction Of Labour ◽  
Cervical Ripening ◽  
Labour Induction ◽  
Term Pregnancy ◽  
Vaginal Tablet ◽  
Misoprostol Group ◽  
Group A ◽  
Vaginal Misoprostol ◽  
Group B

Background: Induction of labour is one of the most common obstetric interventions worldwide. The study was conducted to compare the efficacy and safety of 25µg (low dose) vaginal Misoprostol with intracervical Dinoprostone for cervical ripening and induction of labour in term pregnancy. Methods: For the purpose of this study, 100 term pregnancy patients (only primigravidae and second gravidae) were included who had spontaneous rupture of membrane before onset of labor. Data was collected from cases admitted in labor room at Pannadhay Mahila Chikitsalaya associated with RNT Medical College,Udaipur between July 2014 to July 2015. Results: Requirement of Oxytocin for augmentation of labor between group A and group B. It is evident from the table that oxytocin was required in only 16% of patients in group A, while 46% in group B. This indicates that requirement of oxytocin was significantly less in misoprostol group (P<0.001). Conclusion: This study was designed to assess efficacy of a 25 μg misoprostol vaginal tablet, Finding confirms that vaginal misoprostol tablet is as effective as dinoprostone in cervical ripening and labour induction with dinoprostone. Keywords: Cervical ripening, Dinoprostone, Labour induction, Low- dose misoprostol.

scholarly journals Maternal and neonatal outcome after the use of low dose sublingual 25 µg misoprostol for labour induction in women with term pregnancy

2021 ◽  
Vol 10 (10) ◽  
pp. 3817
Author(s):  
Sumitra Gajraj ◽  
Anupam Kapur
Keyword(s):  
Low Dose ◽  
Neonatal Outcome ◽  
Induction Of Labour ◽  
Cervical Ripening ◽  
Labour Induction ◽  
Care Hospital ◽  
Term Pregnancy ◽  
Total Study Population ◽  
Qualitative Variables ◽  
Study Population

Background: Aim of this study was to assess the maternal and fetal/neonatal outcome after the use of low dose (25 µg) misoprostol for labour induction in women with term pregnancy (gestational age >37 weeks POG) with a live foetus.Methods: The prospective interventional study was designed at the department of obstetrics and gynaecology of a tertiary health care hospital, with a sample size of 150 pregnant ladies who had to undergo induction of labour, were selected depending on the defined inclusion and exclusion criteria. Data was analysed using SPSS 18. Descriptive statistics were used to describe the data. Qualitative variables were presented as frequencies and percentage.Results: About 41% (61 patients) of the total study population was in the age group of 26 to 30 years with only two patients aged >35 years of age. The study group comprised of 88 primigravida (59%) and 62 multigravida (41%). The most common indication for induction of labour in my study was post-dated pregnancy (47%) followed by PROM (22%).Conclusions: The use of low dose (25 µg) misoprostol sublingually is definitely very effective in cervical ripening and induction of labour in term pregnancies particularly in those with poor Bishops score. There was no significant neonatal or maternal morbidity associated with induction of labour with low dose sublingual misoprotol. 

scholarly journals Comparison of low dose vaginal misoprostol with Foley catheter balloon as preinduction cervical ripening agents in term pregnancies

2020 ◽  
Vol 1 ◽  
pp. 10
Author(s):  
Dalyop Davou Nyango ◽  
Daloek M ◽  
Kahansim ML
Keyword(s):  
Pregnant Women ◽  
Low Dose ◽  
Foley Catheter ◽  
Comparative Trial ◽  
Tertiary Hospital ◽  
Cervical Ripening ◽  
Catheter Group ◽  
Misoprostol Group ◽  
Uterine Hyperstimulation ◽  
Vaginal Misoprostol

Objective: One of the obstetricians’ nightmare is managing high-risk pregnancies. Also, the emerging trend by pregnant women requesting for specific delivery dates for social reasons adds to this burden. In both instances, the obstetrician is faced with the challenge of inducing labor where the cervix is still unfavorable. The objective of the study was to compare the effectiveness of loe dose vaginal misoprostol and transcervical extra-amniotic Foley catheter balloon as pre-induction cervical ripening agents in term pregnancies. Material and Methods: This was a prospective, single-blind, randomized comparative trial at a tertiary hospital. Pregnant women at term in whom induction of labor was indicated, who made the inclusion criteria and who gave their consent were randomly assigned to either the vaginal misoprostol or the Foley catheter balloon group. Oxytocin was used for the augmentation of labor subsequent to the artificial rupture of the membranes according to the departmental protocols. Results: One hundred and fifty women were recruited and randomized (75 in each group). In the misoprostol group, 58 (77.3%) women achieved cervical ripening (cervical dilation of ≥4) within 12 h, compared to 43 (57.3%) in the Foley catheter balloon group. Spontaneous vaginal delivery within 12 h was 88.0% and 66.3% in the misoprostol and Foley catheter group, respectively. However, 34.7% in misoprostol group had precipitate labor (induction-to-delivery interval ≤3 h), while 9.3% in the Foley catheter group had prolonged labor. There were no significant differences in the incidence of meconium staining and 1st min Apgar scores of the babies in the two groups. Conclusion: Low dose (25 μg) vaginal misoprostol is a more effective pre-induction cervical ripening agent compared to the conventional transcervical extra-amniotic Foley catheter balloon method. While uterine hyperstimulation is the major risk in the misoprostol group, long induction-to-delivery interval is associated with labors induced following use of Foley catheter balloon as the pre-induction cervical ripening agent.

scholarly journals Oral Versus Vaginal Misoprostol for Induction of Labour

1970 ◽  
Vol 24 (2) ◽  
pp. 44-49 ◽  
Author(s):  
N Sultana ◽  
S Rouf ◽  
M Rashid
Keyword(s):  
Pregnant Women ◽  
Mode Of Delivery ◽  
Induction Of Labour ◽  
Cervical Ripening ◽  
Singleton Pregnancy ◽  
College Hospital ◽  
Nulliparous Women ◽  
Unfavourable Cervix ◽  
Oral Group ◽  
Vaginal Misoprostol

It is sometimes difficult to select the most effective, easy to use, safest, widely accepted and less expensive method for induction of labour and thereby spontaneous vaginal delivery. Prostaglandin E1 analogue ie misoprostol as a successful method both in oral and vaginal form has been used for induction of labour. The present study was conducted with an aim to compare the efficacy and safety of oral and vaginal administration of misoprostol tablets for cervical ripening and induction of labour in pregnant women using similar dosing regimen in two groups of pregnant women. A prospective randomized trial was done on one hundred pregnant women for the purpose. They were between 37 and 42 weeks of gestation with singleton pregnancy, cephalic presentation and unfavourable cervix (modified Bishops score of 4 or less) in the department of Obstetrics and Gynaecology of Dhaka Medical college Hospital during the period between February 2003 and March 2004. The mode of delivery did not vary significantly between the two groups. Mean induction delivery interval, mean doses of misoprostol, number of women delivered within 24 hours, oxytocin requirement and mean time to delivery were nearly similar in the two groups. Only nulliparous women in oral group took longer time to deliver than vaginal group though it was not statistically significant. The mode of delivery also did not differ significantly. The proportion of emergency caesarean section was high in vaginal group than oral group. Neonatal outcome was satisfactory and the results were comparable. (J Bangladesh Coll Phys Surg 2006; 24: 44-49)

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