scholarly journals Extraskeletal myxoid chondrosarcoma of thigh: a rare case report

2021 ◽  
Vol 9 (6) ◽  
pp. 1778
Author(s):  
Pinal C. Shah ◽  
R. N. Hathilal ◽  
Sheetal Sheth ◽  
Smita S. Gavit
Keyword(s):  
Soft Tissue ◽  
Needle Aspiration ◽  
Soft Tissue Tumors ◽  
Extraskeletal Myxoid Chondrosarcoma ◽  
Morphological Examination ◽  
Soft Tissue Neoplasm ◽  
Myxoid Chondrosarcoma ◽  
Neoplastic Lesion ◽  
Rare Case Report ◽  
Needle Aspiration Cytology

Extraskeletal myxoid chondrosarcoma (EMC) are a rare entity of soft tissue tumors that occur predominantly in soft tissue of lower extremities. Here we present a case of 45-year-old female presented with left thigh swelling. MRI finding suggested primary neoplastic lesion. Fine needle aspiration cytology (FNAC) suggested myxoid soft tissue neoplasm/sarcoma. Morphological examination revealed typical extraskeletal myxoid chondrosarcoma with strong immunoreactivity for vimentin and focal immunoreactivity for epithelial membrane antigen (EMA).

scholarly journals Primary Extraskeletal Myxoid Chondrosarcoma: A Case Report

2021 ◽  
Author(s):  
Renuka Bangalore Nagaraj ◽  
Arshiya Sultana
Keyword(s):  
Case Report ◽  
Soft Tissue ◽  
Histopathological Examination ◽  
Matrix Material ◽  
Needle Aspiration ◽  
Extraskeletal Myxoid Chondrosarcoma ◽  
Soft Tissue Neoplasm ◽  
Rare Tumour ◽  
Myxoid Chondrosarcoma ◽  
Malignant Soft Tissue

Extraskeletal Myxoid Chondrosarcoma (EMC) is a rare malignant soft tissue sarcoma with uncertain differentiation, most often seen in males. The incidence is 3% of all soft tissue tumours with limited literature available on its cytological features. EMC may arise from lower extremities, upper extremities, retroperitoneum, pelvis, and buttocks. This case report was an effort to understand the role of Fine Needle Aspiration Cytology (FNAC), histopathology and immunochemistry in the diagnosis of EMC. Authors hereby report a case of a 70-year-old male patient with slow-growing soft tissue swelling on the back just behind the right shoulder who was referred for FNAC. Patient complete history and clinical findings were recorded. Radiological images were suggestive of malignant soft tissue neoplasm with no involvement of underlining bone. FNAC reveled tumour cells which appeared monotonous and they were seen in a myxoid stroma background. Subsequently, the excised lesion was sent for histopathological examination and the report revealed the presence of abundant chondromyxoid matrix material within which were found numerous elongated spindly shaped cells. These cells had moderately pleomorphic elongated nuclei with focal solid fibrocollagenous areas along intersecting fascicles of the moderately pleomorphic spindly cell. Few of these cells had multilobulated bizarre nuclei with nuclear inclusions. Immunohistochemical stains showed diffuse positivity for S-100, vimentin, and focally positive for Epithelial Membrane Antigen (EMA). The FNAC, histopathology and immunohistochemical features confirm the diagnosis of EMC on right shoulder. It’s a rare tumour whose diagnosis is made depending on history, clinical location, growth pattern, histopathology, and immunohistochemistry.

scholarly journals Efficacy of fine needle aspiration cytology in diagnosing soft tissue tumors

2012 ◽  
Vol 2 (4) ◽  
pp. 305-308 ◽  
Author(s):  
S Parajuli ◽  
M Lakhey
Keyword(s):  
Soft Tissue ◽  
Fine Needle Aspiration ◽  
Fine Needle Aspiration Cytology ◽  
Needle Aspiration ◽  
Soft Tissue Tumors ◽  
Aspiration Cytology ◽  
Fine Needle ◽  
Benign Soft Tissue Tumors ◽  
Needle Aspiration Cytology ◽  
Malignant Soft Tissue

Background: Fine needle aspiration cytology has an established role in the diagnosis of various neoplastic and non-neoplastic lesions. Its accuracy when applied by experienced and well trained practitioners matches that of histopathology in providing an equivocal diagnosis; so it can also be used as a very useful alternative to excision biopsy in the diagnostic workup of soft tissue tumors.Materials and Methods: This retrospective study was done in the Department of Pathology, Kathmandu Medical College for a period of one year from January 2006 to December 2006. A total of 60 cases presented with soft tissue tumors, of which only 50 were biopsied and the correlation done. A detailed history, clinical findings, routine relevant laboratory investigations and radiological findings were carried.Results: Fine needle aspiration cytology revealed diagnostic materials in 47 cases and 3 cases were inconclusive for a definite diagnosis. 40 cases were diagnosed as benign lesions and 7 cases as malignant lesions. Out of the benign cases, the most common were lipomas which accounted for 52.5% of cases followed by benign mesenchymal tumor- 17.5%. Out of the malignant cases 71.42% were diagnosed as malignant mesenchymal tumor and 28.57% as malignant nerve sheath tumor. The overall diagnostic accuracy of fine needle aspiration cytology in soft tissue tumors in the present study was 86%. The sensitivity and specificity of diagnosing benign soft tissue tumors was 97.36% and 66.67% respectively and for malignant soft tissue tumors 66.67% and 97.36% respectively.Conclusion: Fine needle aspiration cytology can be effective and reliable diagnostic tool in the evaluation of soft tissue tumors. It is highly sensitive to detect benign soft tissue tumors and highly specific for malignant soft tissue tumors.Journal of Pathology of Nepal (2012) Vol. 2, 305-308DOI: http://dx.doi.org/10.3126/jpn.v2i4.6884

scholarly journals Role of fine needle aspiration cytology in the diagnosis of soft tissue tumors - a prospective study

2019 ◽  
Vol 5 (8) ◽  
pp. 535-541
Author(s):  
Dr. Lakshmi Saraswathi Boni ◽  
◽  
Dr. Sumalatha Kasturi ◽  
Dr. Prasad Uma ◽  
Dr. Bhagyalakshmi Atla ◽  
...  
Keyword(s):  
Soft Tissue ◽  
Prospective Study ◽  
Fine Needle Aspiration ◽  
Needle Aspiration ◽  
Soft Tissue Tumors ◽  
Aspiration Cytology ◽  
Fine Needle ◽  
Needle Aspiration Cytology ◽  
A Prospective Study
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