Quality of life assessment in patients of bladder cancer with radical cystectomy and ileal conduit

Background: Bladder cancer, a lethal disease accounts for 3% of cancer deaths. With possibility of various urinary diversion options after bladder removal having comparable cancer control and complications, quality of life becomes an important factor in deciding the type of urinary diversion.Methods: Retrospective observational study with statistically appropriate sample size of 50. Patients of radical cystectomy and ileal conduit given validated Functional Assessment Of Chronic Illness Therapy for Bladder Cancer ( FACT-Bl ) Questionnaire to answer about post-operative quality of life in terms of five parameters i.e., physical, mental, social, emotional and cancer specific well-being after 1 year of surgery.Results: Results analysed by FACIT-Bl questionnaire analysis methods statistically, in terms of total scores and sub-scores. In our study the mean scores of physical well-being (PWB) subscale is 24.08±4.67 (range o-28), social well-being (SWB) subscale is 23.52±4.35 (range 0-28) , emotional well-being (EWB) subscale is 20.06±5.09, functional well-being (FWB) subscale is 21.84±6.01 (range 0-28), bladder cancer subscale is 36.44±5.72 (range 0-48). While mean trial outcome index score is 82.16±3.5 (range 0-104), FACT- General (G) score is 89.50+ 15.88 and mean FACT-Bl total score is 125.94±19.04.These scores provides the quantitative assessment of the quality of life and higher scores indicates better quality of life.Conclusions: Assessing quality of life for a particular type of urinary diversion, with questionnaires, gives surgeons and patients, guidance regarding diversion of choice.

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Morbidity and Quality of Life in Bladder Cancer Patients following Cystectomy and Urinary Diversion: A Single-Institution Comparison of Ileal Conduit versus Orthotopic Neobladder

ISRN Urology ◽

10.5402/2012/342796 ◽

2012 ◽

Vol 2012 ◽

pp. 1-8 ◽

Cited By ~ 14

Author(s):

Barbara Erber ◽

Mark Schrader ◽

Kurt Miller ◽

Martin Schostak ◽

Daniel Baumunk ◽

...

Keyword(s):

Quality Of Life ◽

Bladder Cancer ◽

Radical Cystectomy ◽

Urinary Diversion ◽

Ileal Conduit ◽

Oncological Outcome ◽

University Hospital ◽

Ileal Neobladder ◽

Eortc Qlq

Objective. To evaluate and compare noncontinent and continent urinary diversion after radical cystectomy in patients with bladder cancer. Methods. A total of 301 patients submitted to radical cystectomy at the Charité-University Hospital Berlin from 1993 to 2007 including 146 with an ileal conduit and 115 with an ileal neobladder. Clinical and pathological data as well as oncological outcome were retrospectively analyzed and compared. Quality of life was analyzed using the EORTC QLQ-C30 and BLM30 questionnaires. Results. 69.1% and 69.6% of all patients who received an ileal conduit and ileal neobladder, respectively, developed early complications. The two groups differed significantly concerning the occurrence of postoperative ileus (P=0.02) favoring patients who received an ileal conduit but not with regard to any other early-onset complication evaluated. Patients with ileal neobladder had a significantly better global health status and quality of life (P=0.02), better physical functioning (P=0.02), but also a higher rate of diarrhoea (P=0.004). Conclusion. Cystectomy with any type of diversion remains a complication-prone surgery. Even if the patient groups are not homogeneous in all respects, there are many arguments in favor of the ileal neobladder as the urinary diversion of choice.

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