scholarly journals Early complications and prognosis with multiple organ system failure score

2021 ◽  
Vol 8 (2) ◽  
pp. 668
Author(s):  
Kaushik Das ◽  
Junaid M. Shaikh ◽  
Ketika Potey ◽  
Sarojini P. Jadhav

Background: Acute pancreatitis is a common surgical entity with a wide clinical spectrum ranging from mild pancreatitis to severe acute pancreatitis with lethal complications. A number of scoring systems have been devised to predict and manage complications associated with severe acute pancreatitis. The objective of this study was to study the demographics, early complications of acute pancreatitis with their outcome, and to assess the efficacy of multi organ system failure score.  Methods: This was a descriptive study including 120 patients of acute pancreatitis done over a period of 2 years. The management of complications and their outcome were recorded in detail. A multi organ system failure score was used to predict and assess the severity of acute pancreatitis. Results: Total 120 patients were evaluated with mean age of 40 years and male preponderance. Alcohol consumption was the most common etiological factor. Acute fluid collection was the most common local complication while shock was the most common systemic complication. MOSF scoring system had a sensitivity, specificity and positive predictive value of 96%, 92.8% and 90.5% respectively. Mortality was 5.8% seen in patients with MOSF score above 5.Conclusions: The management of early complications of acute pancreatitis is mainly conservative, with surgical management limited to only a few selected patients. MOSF score is a valuable tool to predict and assess the severity of acute pancreatitis and should be used for monitoring of high risk patients.

1994 ◽  
Vol 22 (6) ◽  
pp. 1025-1031 ◽  
Author(s):  
FRANÇOIS PROULX ◽  
MARIE GAUTHIER ◽  
DANIEL NADEAU ◽  
JACQUES LACROIX ◽  
CATHERINE ANN FARRELL

1988 ◽  
Vol 7 (9) ◽  
pp. 671-672 ◽  
Author(s):  
Juan A. Hervás ◽  
Paulino López ◽  
Angeles de la Fuente ◽  
Pedro Alomar

1986 ◽  
Vol 14 (4) ◽  
pp. 271-274 ◽  
Author(s):  
JAMES D. WILKINSON ◽  
MURRAY M. POLLACK ◽  
URS E. RUTTIMANN ◽  
NANCY L. GLASS ◽  
TIMOTHY S. YEH

Author(s):  
Abderrezak Bouchama

Hyperthermia is a state of elevated core temperature that rises rapidly above 40°C, secondary to failure of thermoregulation. Hyperthermia has many causes, but it is the hallmark of three conditions—heatstroke, malignant hyperthermia, and neuroleptic malignant syndrome. The clinical and metabolic alterations of hyperthermia, if left untreated, can culminate in multiple organ system failure and death. High temperature causes direct cellular death and tissue damage. The extent of tissue injury is a function of the degree and duration of hyperthermia. Heat-induced ischaemia-reperfusion injury, and exacerbated activation of inflammation and coagulation are also contributory. Hyperthermia is a true medical emergency with rapid progression to multiple organ system failure and death. The primary therapeutic goal is to reduce body temperature as quickly as possible using physical cooling methods, and if indicated, the use of pharmacological treatment to accelerate cooling. There is no evidence of the superiority of one cooling technique over another. Non-invasive techniques that are easy to use and well-tolerated are preferred. Pharmacological cooling with Dantrolene sodium is crucial in the treatment of malignant hyperthermia.


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