scholarly journals A case of Henoch‐Schonlein purpura presenting with pulmonary involvement

2021 ◽  
Vol 8 (3) ◽  
pp. 462
Author(s):  
Parth Patel ◽  
Sudhendu Patel ◽  
Ramila Patel ◽  
Varsha Aswani

Pulmonary involvement in Henoch‐Schonlein purpura (HSP) although rare is an important treatable cause of hospital admission in patients. Its diagnosis is difficult due to the vague symptoms and non-specific radiographic findings. We present one such case of a known case of HSP presenting with pulmonary involvement and treated successfully with steroids and immunosuppressant medications after ruling out all other causes. This particular case could also have an additional component of methotrexate induced lung involvement. Overall it is an interesting case with some much needed learning points.  

2019 ◽  
Vol 17 (1) ◽  
Author(s):  
Giada Maria Di Pietro ◽  
Massimo Luca Castellazzi ◽  
Antonio Mastrangelo ◽  
Giovanni Montini ◽  
Paola Marchisio ◽  
...  

Abstract Background Henoch-Schönlein Purpura (HSP) is the most common vasculitis of childhood and affects the small blood vessels. Pulmonary involvement is a rare complication of HSP and diffuse alveolar hemorrhage (DAH) is the most frequent clinical presentation. Little is known about the real incidence of lung involvement during HSP in the pediatric age and about its diagnosis, management and outcome. Methods In order to discuss the main clinical findings and the diagnosis and management of lung involvement in children with HSP, we performed a review of the literature of the last 40 years. Results We identified 23 pediatric cases of HSP with lung involvement. DAH was the most frequent clinical presentation of the disease. Although it can be identified by chest x-ray (CXR), bronchoalveolar lavage (BAL) is the gold standard for diagnosis. Pulse methylprednisolone is the first-line of therapy in children with DAH. An immunosuppressive regimen consisting of cyclophosphamide or azathioprine plus corticosteroids is required when respiratory failure occurs. Four of the twenty-three patients died, while 18 children had a resolution of the pulmonary involvement. Conclusions DAH is a life-threatening complication of HSP. Prompt diagnosis and adequate treatment are essential in order to achieve the best outcome.


2006 ◽  
Vol 23 (11) ◽  
pp. 886-886 ◽  
Author(s):  
A Soloukides ◽  
D-A Moutzouris ◽  
G Metaxatos ◽  
V Hadjiconstantinou

2013 ◽  
Vol 75 (2) ◽  
pp. 119-122
Author(s):  
Sayuri SATO ◽  
Hiroyuki TAKAHASHI ◽  
Noriko MIZUKAKI ◽  
Makiko KAGAYA ◽  
Hiroyuki TAKAHASHI ◽  
...  

Pediatru ro ◽  
2020 ◽  
Vol 2 (58) ◽  
pp. 42
Author(s):  
Alice Azoicăi ◽  
Maria-Ruxandra Cepoi ◽  
Bogdan A. Stana

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