scholarly journals Recent update in ultrasound contrast agents

2016 ◽  
Vol 2 (10) ◽  
pp. 274 ◽  
Author(s):  
Poonam Vohra ◽  
Kusum Jasuja
Keyword(s):  
Contrast Agents ◽  
Complex Structure ◽  
Blood Perfusion ◽  
Blood Flow Rate ◽  
Systemic Circulation ◽  
Ultrasound Contrast Agents ◽  
The Body ◽  
Sound Waves ◽  
Ultrasound Waves ◽  
Ultrasound Contrast

<p>Contrast-enhanced ultrasound (CEUS) is the application of ultrasound contrast medium to traditional medical sonography. Ultrasound contrast agents rely on the different ways in which sound waves are reflected from interfaces between substances. This may be the surface of a small air bubble or a more complex structure. Commercially available contrast media are gas-filled microbubbles that are administered intravenously to the systemic circulation. Microbubbles have a high degree of echogenicity (the ability of an object to reflect ultrasound waves). There is a great difference in echogenicity between the gas in the microbubbles and the soft tissue surroundings of the body. Thus, ultrasonic imaging using microbubble contrast agents enhances the ultrasound backscatter, (reflection) of the ultrasound waves, to produce a sonogram with increased contrast due to the high echogenicity difference. CEUS can be used to image blood perfusion in organs, measure blood flow rate in the heart and other organs, and for other applications.</p>

Stabilized bubbles in the body: pressure-radius relationships and the limits to stabilization

1997 ◽  
Vol 82 (6) ◽  
pp. 2045-2053 ◽  
Author(s):  
Hugh D. Van Liew ◽  
Soumya Raychaudhuri
Keyword(s):  
Contrast Agents ◽  
Conceptual Framework ◽  
Bubble Radius ◽  
Ultrasonic Imaging ◽  
Ultrasound Contrast Agents ◽  
The Body ◽  
Strong Growth ◽  
Ultrasound Contrast ◽  
Practical Usefulness

Van Liew, Hugh D., and Soumya Raychaudhuri. Stabilized bubbles in the body: pressure-radius relationships and the limits to stabilization. J. Appl. Physiol.82(6): 2045–2053, 1997.—We previously outlined the fundamental principles that govern behavior of stabilized bubbles, such as the microbubbles being put forward as ultrasound contrast agents. Our present goals are to develop the idea that there are limits to the stabilization and to provide a conceptual framework for comparison of bubbles stabilized by different mechanisms. Gases diffuse in or out of stabilized bubbles in a limited and reversible manner in response to changes in the environment, but strong growth influences will cause the bubbles to cross a threshold into uncontrolled growth. Also, bubbles stabilized by mechanical structures will be destroyed if outside influences bring them below a critical small size. The in vivo behavior of different kinds of stabilized bubbles can be compared by using plots of bubble radius as a function of forces that affect diffusion of gases in or out of the bubble. The two ends of the plot are the limits for unstabilized growth and destruction; these and the curve’s slope predict the bubble’s practical usefulness for ultrasonic imaging or O2 carriage to tissues.

Ultrasound contrast agents: microbubbles made simple for the pediatric radiologist

2021 ◽  
Author(s):  
Anush Sridharan ◽  
John R. Eisenbrey ◽  
Flemming Forsberg ◽  
Norbert Lorenz ◽  
Ludwig Steffgen ◽  
...  
Keyword(s):  
Contrast Agents ◽  
Ultrasound Contrast Agents ◽  
Pediatric Radiologist ◽  
Ultrasound Contrast

scholarly journals New Applications in Echocardiography for Ultrasound Contrast Agents in the 21st Century

2020 ◽  
Vol 46 (5) ◽  
pp. 1071-1081 ◽  
Author(s):  
Thomas R. Porter ◽  
Steve B. Feinstein ◽  
Folkert J. Ten Cate ◽  
Annemien E. van den Bosch
Keyword(s):  
Contrast Agents ◽  
21St Century ◽  
Ultrasound Contrast Agents ◽  
Ultrasound Contrast ◽  
New Applications

Emerging Applications of Ultrasound-Contrast Agents in Radiation Therapy

2021 ◽  
Vol 47 (6) ◽  
pp. 1465-1474
Author(s):  
Quezia Lacerda ◽  
Mohamed Tantawi ◽  
Dennis B. Leeper ◽  
Margaret A. Wheatley ◽  
John R. Eisenbrey
Keyword(s):  
Radiation Therapy ◽  
Contrast Agents ◽  
Ultrasound Contrast Agents ◽  
Ultrasound Contrast
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