scholarly journals Capillaroscopic nail fold changes in collagen vascular diseases: A prospective observational study from a tertiary care teaching hospital in Western India

2021 ◽  
Vol 7 (4) ◽  
pp. 347-352
Author(s):  
Ratnakar Shukla ◽  
Sheena Kapoor ◽  
Sharmila Patil ◽  
Anant Patil
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Systemic Sclerosis ◽  
Observational Study ◽  
Lupus Erythematosus ◽  
Prospective Observational Study ◽  
Raynaud’S Phenomenon ◽  
Tertiary Care ◽  
Vascular Diseases ◽  
Systemic Lupus ◽  
Collagen Vascular Diseases

: To examine nail changes with capillaroscopy in patients with collagen vascular diseases. In this prospective observational study, patients with collagen vascular diseases presented to dermatology outpatient department of a tertiary care center were subjected to capillaroscopy. Structural and morphological abnormalities in these patients were noted. Fifty patients (Mean age 38.2 years; 86% females) with mean disease duration of 1.96 years were included. Patients with systemic sclerosis and systemic lupus erythematosus constituted 34% and 32% patients respectively. Twenty two (44%) patients had presence of dilated nail fold capillary loops. Out of 17 patients with systemic sclerosis, 15(88.23%) and 14(87.5%) showed dilated nail fold capillary loops and capillary drop-pouts respectively. Capillary dropouts were observed in 14(82.35%) patients. Raynaud’s phenomenon, splinter hemorrhage and fingertip scarring was observed in 11(64.71%), six (35.29%) and 33(17.65%) patients respectively. Ragged cuticle was observed in four (25%) patients with systemic lupus erythematosus. In our study, systemic sclerosis and systemic lupus erythematosus were two most common disorders. Dilated nail fold capillary loops/giant capillaries were the most common observation in overall population. Dilated nail fold capillary loops, capillary dropouts, Raynaud’s phenomenon, splinter hemorrhage and fingertip scarring were common in patients with systemic sclerosis.

Systemic sclerosis

2010 ◽  
pp. 3664-3678
Author(s):  
Christopher P. Denton ◽  
Carol M. Black
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Systemic Sclerosis ◽  
Lupus Erythematosus ◽  
Raynaud’S Phenomenon ◽  
Raynaud's Phenomenon ◽  
Systemic Lupus ◽  
Overlap Syndromes ◽  
Autoimmune Rheumatic Disease ◽  
Skin Sclerosis ◽  
Important Form

The scleroderma spectrum of disorders includes a number of diseases that have Raynaud’s phenomenon or skin sclerosis in common, comprising (1) limited cutaneous scleroderma; (2) systemic sclerosis (SSc)—the most important form of scleroderma—limited cutaneous SSc, diffuse cutaneous SSc, and overlap syndromes (with features of another autoimmune rheumatic disease, e.g. systemic lupus erythematosus); (3) Raynaud’s phenomenon—autoimmune (with antinuclear or other SSc-associated antibodies) or primary. These conditions affect women four times as often as men, most often beginning in the fifth decade....

scholarly journals Liver Abnormalities in Systemic Lupus Erythematosus: A Prospective Observational Study

Cureus ◽  
2021 ◽  
Author(s):  
Shaik Imran ◽  
Molly Mary Thabah ◽  
Mohamed Azharudeen ◽  
Ananthakrishnan Ramesh ◽  
Zachariah Bobby ◽  
...  
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Observational Study ◽  
Lupus Erythematosus ◽  
Prospective Observational Study ◽  
Systemic Lupus

A CASE OF TUBERCULOUS TENOSYNOVITIS IN A PATIENT WITH SYSTEMIC LUPUS ERYTHEMATOSUS

Hand Surgery ◽  
2004 ◽  
Vol 09 (01) ◽  
pp. 109-113 ◽  
Author(s):  
M. Oshima ◽  
A. Fukui ◽  
Y. Takakura
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Steroid Therapy ◽  
Lupus Erythematosus ◽  
Histopathological Examination ◽  
Vascular Diseases ◽  
Steroid Treatment ◽  
Systemic Lupus ◽  
Collagen Vascular Diseases ◽  
Increased Risk ◽  
Tuberculous Tenosynovitis

A 52-year-old woman with systemic lupus erythematosus (SLE) was infected with tuberculosis (TB) on her forearm and hand, after 16 years of steroid therapy. Debridements and anti-TB therapy were performed successfully. Recently, the risk of significant morbidity from TB has been on the rise; this appears to be a complication of steroid therapy used to treat AIDS and some collagen vascular diseases. It is thought that steroid therapy causes an increased risk of TB. In this paper, we report our experience of this SLE patient who developed tuberculous tenosynovitis. We suggest that TB infection must be considered in the differential diagnosis whenever a patient presents with a chronic wrist or hand inflammation that is non-responsive to steroid treatment. Once TB infection is suspected, both histopathological and bacteriological examinations should be performed. Emergent treatment includes surgical debridement and the institution of early anti-TB therapy immediately after completing histopathological examination.

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