Appendectomized Patient and Infections after Surgery

Appendicitis is one of the common surgeries all over the world, and its diagnosis is difficult and based on clinical examinations or its symptoms. Moreover, after the surgery is accomplished, it is probable that the patient is faced with certain problems and complications. In this regard, the present study was carried out in order to review the infections caused after appendicitis surgery. The databases like PubMed, Google Scholar, and Science Direct and relevant articles were collected, in which keywords like appendicitis surgery, perforation, laparoscopy, and infection had been used. A total number of 6,000 articles were retrieved, out of which, 74 relevant articles were examined. The results of the present study indicated that perforated appendix can be the biggest cause of infection and abscess after intra-abdominal surgery. An increase in the level of C-reactive protein and leukocytes is accompanied with the risk of postoperative complications including infection and abscess. Numerous studies have reported that formation of infection and abscess after laparoscopic appendectomy is a little more than open appendectomy. It is not necessary to consume antibiotics after a non-perforated appendectomy. It is sufficient to consume antibiotics for 3 to 5 days after a perforated appendectomy to prevent infection and abscess. With the above results now it is evident that the appendicitis and its complications are still a common problem among people all over the world. There is still much to discuss among the surgeons with regards to appendicitis and its complications.

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Appendectomized Patient and Infections after Surgery

Asian Journal of Pharmaceutical Research and Health Care ◽

10.18311/ajprhc/2016/7721 ◽

2016 ◽

Vol 8 (1) ◽

pp. 36

Author(s):

Mohammad Reza Asgary ◽

Hosein Hemmati

Keyword(s):

Postoperative Complications ◽

Abdominal Surgery ◽

Laparoscopic Appendectomy ◽

Open Appendectomy ◽

Google Scholar ◽

C Reactive Protein ◽

Reactive Protein ◽

The World ◽

Perforated Appendix ◽

The Common

Appendicitis is one of the common surgeries all over the world, and its diagnosis is difficult and based on clinical examinations or its symptoms. Moreover, after the surgery is accomplished, it is probable that the patient is faced with certain problems and complications. In this regard, the present study was carried out in order to review the infections caused after appendicitis surgery. The databases like PubMed, Google Scholar, and Science Direct and relevant articles were collected, in which keywords like appendicitis surgery, perforation, laparoscopy, and infection had been used. A total number of 6,000 articles were retrieved, out of which, 74 relevant articles were examined. The results of the present study indicated that perforated appendix can be the biggest cause of infection and abscess after intra-abdominal surgery. An increase in the level of C-reactive protein and leukocytes is accompanied with the risk of postoperative complications including infection and abscess. Numerous studies have reported that formation of infection and abscess after laparoscopic appendectomy is a little more than open appendectomy. It is not necessary to consume antibiotics after a non-perforated appendectomy. It is sufficient to consume antibiotics for 3 to 5 days after a perforated appendectomy to prevent infection and abscess. With the above results now it is evident that the appendicitis and its complications are still a common problem among people all over the world. There is still much to discuss among the surgeons with regards to appendicitis and its complications.

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Peer Review #1 of "Is the Neutrophil-to-Lymphocyte Ratio more correlated than C-reactive protein with postoperative complications after major abdominal surgery? (v0.1)"

10.7287/peerj.713v0.1/reviews/1 ◽

2015 ◽

Keyword(s):

Postoperative Complications ◽

Abdominal Surgery ◽

Peer Review ◽

Neutrophil To Lymphocyte Ratio ◽

Major Abdominal Surgery ◽

C Reactive Protein ◽

Lymphocyte Ratio ◽

Reactive Protein

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C-reactive protein and procalcitonin as a predictive factors on appearance of postoperative complications after open appendectomy in children

Srpski arhiv za celokupno lekarstvo ◽

10.2298/sarh160505038m ◽

2017 ◽

Vol 145 (5-6) ◽

pp. 265-270

Author(s):

Vesna Marjanovic ◽

Ivana Budic ◽

Andjelka Slavkovic ◽

Vladimir Radlovic ◽

Dusica Simic

Keyword(s):

Postoperative Complications ◽

Rectal Temperature ◽

Open Appendectomy ◽

C Reactive Protein ◽

Laboratory Parameters ◽

Reactive Protein ◽

Prolonged Hospitalization ◽

Uncomplicated Appendicitis ◽

Surgical Conditions ◽

Prediction Of Complications

Introduction/Objective. Acute appendicitis is one of the most common surgical conditions in children that may be followed by inflammatory postoperative complications. The aim of this study was to determine the association of the preoperative levels of C-reactive protein (CRP) and procalcitonin (PCT) and occurrence of inflammatory postoperative complications in children with appendicitis. Methods. Fifty-four patients were separated into two groups. The first group contained patients with uncomplicated appendicitis (UA) whereas the second group comprised patients with complicated appendicitis (CA). Clinical and laboratory parameters in preoperative period were used for prediction of complications after open appendectomy in children. Results. Patients with CA had significantly higher values of rectal temperature (p < 0.05), longer length of fever (p < 0.001), CRP (p < 0.001), PCT (p < 0.001), longer duration of stay at the intensive care unit (ICU) (p < 0.001), and prolonged hospitalization (p < 0.001) than the UA group. In the CA group, 41.93% had postoperative complications; these patients also had longer duration of fever (p < 0.05), higher level of CRP (p < 0.05), and prolonged hospitalization (p < 0.01) compared to patients in the CA group without complications. Preoperative cut-off values of CRP and PCT (75.8 mg/l and 0.36 ng/ml, respectively) pointed towards higher probability for development of postoperative complications. Rectal temperature and duration of fever had predictive influence in determination of postoperative complications in the CA group. Conclusion. The cut-off values of preoperative levels of CRP and PCT were able to discriminate the subset of patients with higher risk for postoperative complications. Rectal temperature and duration of fever had predictive influence on the occurrence of postoperative complications, while other clinical and laboratory parameters were not able to predict appearance of the complications after open appendectomy in children.

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Is the Neutrophil-to-Lymphocyte Ratio more correlated than C-reactive protein with postoperative complications after major abdominal surgery?

PeerJ ◽

10.7717/peerj.713 ◽

2015 ◽

Vol 3 ◽

pp. e713 ◽

Cited By ~ 27

Author(s):

Patrice Forget ◽

Valérie Dinant ◽

Marc De Kock

Keyword(s):

Postoperative Complications ◽

Abdominal Surgery ◽

Neutrophil To Lymphocyte Ratio ◽

Major Abdominal Surgery ◽

C Reactive Protein ◽

Lymphocyte Ratio ◽

Reactive Protein

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The role of preoperative C-reactive protein value and neutrophil ratio in determination of conversion from laparoscopic appendectomy to open appendectomy

Turkish Journal of Trauma and Emergency Surgery ◽

10.5505/tjtes.2018.68705 ◽

2018 ◽

Author(s):

Hüseyin Onur Aydın

Keyword(s):

Laparoscopic Appendectomy ◽

Open Appendectomy ◽

C Reactive Protein ◽

Reactive Protein

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Peritonitis from Perforated Appendicitis: Stress Response after Laparoscopic or Open Treatment

The American Surgeon ◽

10.1177/000313481207800541 ◽

2012 ◽

Vol 78 (5) ◽

pp. 582-590 ◽

Cited By ~ 14

Author(s):

Mario Schietroma ◽

Federica Piccione ◽

Francesco Carlei ◽

Marco Clementi ◽

Zuleyka Bianchi ◽

...

Keyword(s):

Systemic Inflammation ◽

Laparoscopic Appendectomy ◽

Neutrophil Elastase ◽

Open Appendectomy ◽

Perforated Appendicitis ◽

Laparoscopic Group ◽

Open Group ◽

C Reactive Protein ◽

Reactive Protein ◽

Hla Dr

Elevated intra-abdominal pressure during laparoscopy may promote systemic inflammatory response. In patients with generalized peritonitis from perforated appendicitis, we sought to compare acute phase response and immunologic status from laparoscopic and open approach. One hundred and forty-seven consecutive patients underwent appendectomy for perforated appendicitis (73 patients had laparoscopic appendectomy and 74 patients had open appendectomy. Bacteremia, endotoxemia, white blood cells, peripheral lymphocytes subpopulation, human leukocyte antigen-DR (HLA-DR), neutrophil-elastase, interleukin-1 and 6 (IL-1 and 6), and C-reactive protein were investigated. One hour after intervention, bacteremia was significantly higher in the open group compared with the laparoscopic group ( P < 0.05). A significantly higher concentration of systemic endotoxin was detected intraoperatively in the open group of patients in comparison with the laparoscopic group ( P < 0.05). Laparotomy caused a significant increase in neutrophil concentration, neutrophil-elastase, IL-1 and 6, and C-reactive protein and a decrease of HLA-DR. We recorded 6 cases (8.1%) of intra-abdominal abscess in the open group and one (1.3%) in the laparoscopic group ( P < 0.05). Open appendectomy, in case of peritonitis, increased the incidence of bacteremia, endotoxemia, and systemic inflammation compared with laparoscopic appendectomy. Early enhanced postoperative systemic inflammation may cause lower transient immunologic defense after laparotomy (decrease of HLA-DR), leading to enhanced sepsis in these patients.

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