scholarly journals THE SINGULAR PRESENTATION OF CUTANEOUS SPINDLE CELL SQUAMOUS CELL CARCINOMA OF THE INGUINAL REGION

2018 ◽  
Vol 5 (48) ◽  
pp. 3348-3350
Author(s):  
Parul Gupta ◽  
Shailley Arora Sehgal ◽  
Anil Kumar Dhull ◽  
Vivek Kaushal
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Spindle Cell ◽  
Inguinal Region

597: How Accurate is the Clinical Assessment of the Inguinal Region in Patients with Squamous Cell Carcinoma of the Penis

2006 ◽  
Vol 175 (4S) ◽  
pp. 193-193 ◽  
Author(s):  
Paul Hadway ◽  
Cathy M. Corbishley ◽  
Matthew Perry ◽  
Nicholas A. Watkin
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Clinical Assessment ◽  
Inguinal Region

Spindle Cell Carcinoma of the Tongue: Fallacies in Its Diagnosis

2018 ◽  
Vol 3 (02) ◽  
Author(s):  
Amrit Kaur Kaler, Shweta C, Smitha Chandra B.C, Rajeev Naik
Keyword(s):  
Squamous Cell Carcinoma ◽  
Oral Cavity ◽  
Cell Carcinoma ◽  
Cell Population ◽  
Squamous Cell ◽  
Spindle Cell ◽  
Spindle Cell Carcinoma ◽  
Biphasic Tumor ◽  
Carcinoma Of The Tongue ◽  
Ihc Markers

Spindle cell carcinoma is a rare aggressive biphasic tumor, composed of neoplastic proliferation of both epithelial (squamous) and spindle cell population. It constitutes about 1% of all oral cavity tumors 2a and is almost rare on the tongue; only few cases have been reported so far. This variant of squamous cell carcinoma, comprises major diagnostic problems due to its varied histomorphology and resemblance to sarcomatous lesion; hence diligent screening and IHC markers are mandatory for its diagnosis.

Clinicopathologic features and outcome of head and neck mucosal spindle cell squamous cell carcinoma

2021 ◽  
Author(s):  
Carlos N. Prieto-Granada ◽  
Bin Xu ◽  
Bayan Alzumaili ◽  
Mohamed Rizwan Haroon Al Rasheed ◽  
Antoine Eskander ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Head And Neck ◽  
Squamous Cell ◽  
Spindle Cell ◽  
Clinicopathologic Features

scholarly journals Unusual Presentation of Cutaneous Spindle Cell Squamous Cell Carcinoma: A Case Report

2020 ◽  
Vol 12 (1) ◽  
pp. 70-75
Author(s):  
Erika Wernheden ◽  
Hannah Trøstrup ◽  
Anette Pedersen Pilt
Keyword(s):  
Squamous Cell Carcinoma ◽  
Lymph Node ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Spindle Cell ◽  
Regional Lymph Node ◽  
Single Cells ◽  
Gluteal Region ◽  
Inguinal Lymph Node Dissection ◽  
Desmoplastic Melanoma

Cutaneous spindle cell squamous cell carcinoma (SpSCC) is a rare and often aggressive subtype of squamous cell carcinoma (SCC), which usually appears in sun-exposed areas, in areas that have received prior ionizing radiation, or in immunosuppressed individuals. SpSCCs are histologically characterized by keratinocytes infiltrating the dermis as single cells with elongated nuclei rather than as cohesive nests or islands and, in contrast to conventional SCC, are lacking features of keratinization. Immunohistochemical studies are useful to distinguish SpSCC from other spindle cell neoplasms, such as spindle cell/desmoplastic melanoma, cutaneous leiomyosarcoma, and atypical fibroxanthoma. We present a rare case of a patient with SpSCC in the gluteal region with regional lymph node metastasis. The patient was treated with wide excision of the tumor, inguinal lymph node dissection, and adjuvant radiotherapy. Cutaneous SpSCC is clinically similar to conventional SCC but can demonstrate more aggressive behavior. This case is rare since it was localized in the gluteal region of an otherwise healthy man.

Clinical Analysis of Laryngeal Spindle Cell Carcinoma

ORL ◽  
2020 ◽  
Vol 82 (6) ◽  
pp. 310-317
Author(s):  
Le Chen ◽  
Qi Chen ◽  
Cai Li ◽  
Liang Zhou ◽  
Shuyi Wang ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Propensity Score ◽  
Cell Carcinoma ◽  
Clinical Features ◽  
Squamous Cell ◽  
Treatment Strategy ◽  
Spindle Cell ◽  
Clinical Analysis ◽  
Spindle Cell Carcinoma ◽  
Seer Database

<b><i>Aims:</i></b> To investigate the clinical features, treatment, and outcomes of laryngeal spindle cell carcinoma (SpCC). <b><i>Methods:</i></b> Between 2005 and 2014, patients from our hospital with SpCC of the larynx were retrospectively analyzed alongside patient data from the SEER database of America. <b><i>Results:</i></b> A total of 11 patients with SpCC of the larynx were diagnosed and underwent surgery in our hospital. All patients were male and all tumors were located in the glottis. The 3- and 5-year OS rates were both 54.5%. In the SEER database, 148 patients were diagnosed with SpCC of the larynx. The 3- and 5-year OS rates were 72.8 and 63.2%, respectively. According to the comparison of propensity score-matched analysis, the OS was longer in squamous cell carcinoma (SCC) of the larynx (<i>p</i> &#x3c; 0.0001). <b><i>Conclusion:</i></b> SpCC of the larynx is rare and typically originates in the glottis. Its prognosis is worse than that of laryngeal SCC, and surgery is a reasonable treatment strategy.

Spindle cell squamous cell carcinoma showing epithelial-mesenchymal transition

2009 ◽  
Vol 23 (2) ◽  
pp. 214-215 ◽  
Author(s):  
H Iwata ◽  
Y Aoyama ◽  
H Kamiya ◽  
Y Ichiki ◽  
Y Kitajima
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Spindle Cell ◽  
Epithelial Mesenchymal Transition ◽  
Mesenchymal Transition
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