scholarly journals Cerebral phaeohyphomycosis due to Rhinocladiella mackenziei in an immunocompetent patient: A case report and review of literature

2020 ◽  
Author(s):  
Muhammad Mushtaq ◽  
Saad Bin Zafar Mahmood ◽  
Nosheen Nasir ◽  
Malik Saad Rashid ◽  
Memoona Irshad ◽  
...  
Keyword(s):  
Case Report ◽  
Granulomatous Inflammation ◽  
Immunocompetent Patient ◽  
Review Of Literature ◽  
Resonance Imaging ◽  
Dematiaceous Fungi ◽  
Limb Weakness ◽  
Diagnostic Skills ◽  
Facial Numbness ◽  
Significant Mortality

Background and Purpose: Rhinocladiella mackenziei is a neurotropic fungus, which can cause devastating intracerebral infections with up to 100% fatality rate. It is difficult to isolate this fungus in laboratory as it grows slowly and requires diagnostic skills. Case report: A 42-year-old Pakistani man presented with headache, facial numbness, progressive upper limb weakness, and dysarthria. Magnetic resonance imaging of thebrain showed a space-occupying lesion in the basal ganglia region. The patient underwent supratentorial craniotomy for biopsy and excision. Histopathology of the specimen revealed granulomatous inflammation with abscess formation. Periodic acidSchiff special stains highlighted the presence of numerous septate fungal hyphae. The results revealed the growth of dematiaceous fungi, which were morphologically classified as R. mackenziei. The patient is currently stable and is being on amphotericin and posaconazole, along with neurorehabilitation therapy. Conclusion: Rhinocladiella mackenziei brain abscess is a devastating infection with significant mortality. This condition should be suspected in patients with brain abscessfrom high endemic areas

scholarly journals Tuberculous Pachymeningitis Presenting as a Diffused Dural Thickening in a Patient with Chronic Headache and Recurrent Neurological Abnormalities for More than a Decade: A Case Report and a Review of the Literature

2018 ◽  
Vol 2018 ◽  
pp. 1-5
Author(s):  
C. L. Fonseka ◽  
T. E. Kanakkahewa ◽  
S. D. A. L. Singhapura ◽  
J. S. Hewavithana ◽  
L. P. Kolambage ◽  
...  
Keyword(s):  
Case Report ◽  
Chronic Headache ◽  
Facial Nerve Palsy ◽  
Extrapulmonary Tuberculosis ◽  
Granulomatous Inflammation ◽  
Mantoux Test ◽  
Resonance Imaging ◽  
Neurological Signs ◽  
Neurological Abnormalities ◽  
Contrast Enhanced

Background. Tuberculous pachymeningitis is a rare form of extrapulmonary tuberculosis usually suspected from the detection of thickening of the dura in contrast-enhanced magnetic resonance imaging. Progressive nature of the disease can lead to chronic headache with focal neurological signs due to compression from the thickened dura. Case Report. We report a 40-year-old female who presented with chronic headache over a decade associated with recurrent neurological abnormalities including optic neuritis, hemisensory loss, migraine, facial nerve palsy, and recurrent vertigo. Although there was an initial perceived response to steroids, the patient had a subsequent progressive course. On investigations, she was found to have a diffused dural thickening on contrast MRI with a strongly positive Mantoux test with caseating necrotizing granulomatous inflammation on dural histology. With initiation of antituberculous medication with steroids, the patient markedly improved, and the medication for tuberculosis was continued for a year with good response. Conclusion. Primary tuberculous pachymeningitis should be suspected in a patient complaining of prolonged headache with focal neurological signs when MRI evidence of dural thickening is detected, and another focus of tuberculosis was not found. Prompt suspicion with image-guided dural biopsy for histology would help to confirm the diagnosis.

scholarly journals Acute disseminated encephalomyelitis after Plasmodium vivax infection: case report and review of literature

2015 ◽  
Vol 7 (2) ◽  
Author(s):  
Jasmeet Sidhu ◽  
Anu Maheshwari ◽  
Raju Gupta ◽  
Veena Devgan
Keyword(s):  
Magnetic Resonance Imaging ◽  
Case Report ◽  
Magnetic Resonance ◽  
Plasmodium Vivax ◽  
Viral Infections ◽  
Acute Disseminated Encephalomyelitis ◽  
Neurological Recovery ◽  
Imaging Findings ◽  
Review Of Literature ◽  
Resonance Imaging

Acute demyelinating encephalomyelitis (ADEM) usually occurs after viral infections or vaccination. Its occurrence after <em>Plasmodium vivax</em> infection is extremely uncommon. We report the case of an 8-year-old girl who had choreo-athetoid movements and ataxia after recovery from <em>P.vivax</em> infection. Diagnosis of ADEM was made on the basis of magnetic resonance imaging findings. The child responded to corticosteroids with complete neurological recovery.

scholarly journals Rhino-orbito-cerebral mucormycosis in an immunocompetent patient: Case report and review of literature

2012 ◽  
Vol 19 (2) ◽  
pp. 258 ◽  
Author(s):  
Ismail Shatriah ◽  
Norazizah Mohd-Amin ◽  
TengkuNorina Tuan-Jaafar ◽  
RajeshKumar Khanna ◽  
Rohaizan Yunus ◽  
...  
Keyword(s):  
Case Report ◽  
Immunocompetent Patient ◽  
Review Of Literature ◽  
Patient Case
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