scholarly journals Central Serous Chorioretinopathy in a Case of Regressed Familial Retinoblastoma

2020 ◽  
Author(s):  
Saeed Karimi ◽  
Amir Arabi ◽  
Toktam Shahraki ◽  
Sare Safi
Keyword(s):  
Optical Coherence Tomography ◽  
Visual Acuity ◽  
Case Report ◽  
Fluorescein Angiography ◽  
Optic Disc ◽  
Central Serous Chorioretinopathy ◽  
Tumor Recurrence ◽  
Late Onset ◽  
Subretinal Fluid ◽  
Fluid Accumulation

Purpose: To present a case of central serous chorioretinopathy (CSC) in association with regressed familial retinoblastoma. Case Report: A 23-year-old man with regressed unilateral familial retinoblastoma in his left eye presented with decreased vision of the left eye since two months ago. The patient had undergone chemotherapy and cryotherapy for the treatment of retinoblastoma 20 years ago. In the left eye, funduscopy disclosed regressed mass of retinoblastoma, inferonasal to the optic disc, and focal subfoveal neurosensory detachment. Optical coherence tomography (OCT) and fluorescein angiography revealed CSC. As there was no sign of recurrence of retinoblastoma and retinal findings did not show late-onset chemotherapy-related retinopathy, the patient was diagnosed with CSC and followed up. After two months, visual acuity of the left eye improved, and repeated macular OCT revealed absorption of the subretinal fluid. Conclusion: Subretinal fluid accumulation in a patient with regressed retinoblastoma is not always a sign of tumor recurrence or a treatment-related retinopathy.

scholarly journals Intravitreal Ziv-Aflibercept in Treatment of Naïve Chronic Central Serous Chorioretinopathy Related Choroidal Neovascular Membrane

2017 ◽  
Vol 2017 ◽  
pp. 1-5
Author(s):  
Nishant Radke ◽  
Charudutt Kalamkar ◽  
Amrita Mukherjee ◽  
Snehal Radke
Keyword(s):  
Optical Coherence Tomography ◽  
Visual Acuity ◽  
Case Report ◽  
Fluorescein Angiography ◽  
Male Patient ◽  
Visual Function ◽  
Central Serous Chorioretinopathy ◽  
Choroidal Neovascular Membrane ◽  
Fundus Fluorescein Angiography ◽  
Chronic Central Serous Chorioretinopathy

Purpose. To study the effect and outcome of intravitreal Ziv-Aflibercept (IVZ) in treatment of Chronic Central Serous Chorioretinopathy (CSCR) related Choroidal Neovascular Membrane (CNVM). Methods. A case report of 48-year-old male patient treated with 1.25 mg/0.05 ml IVZ (total 3 doses at monthly intervals) in CSCR related CNVM. Pre- and posttreatment fundus fluorescein angiography (FFA) and Optical Coherence Tomography (OCT) were done to document response along with improvement in visual acuity. Patients. Single eye of a 48-year-old male patient. Results. Regression of CNVM was noted with improvement of macular contour and thickness on OCT and cessation of leakage on FFA. Visual acuity improved from 3/60, <N36 to 6/12, N12. Discussion. Anti-VEGF injections have shown benefit in treatment of CNVM. There is very little information about benefit of IVZ in CSCR related CNVM. Conclusion. IVZ is effective in regression of CSCR related CNVM and is associated with better macular anatomy and improved visual function.

scholarly journals Bilateral Vitreopapillary Traction Demonstrated by Optical Coherence Tomography Mistaken for Papilledema

2012 ◽  
Vol 2012 ◽  
pp. 1-3 ◽  
Author(s):  
Elizabeth Houle ◽  
Neil R. Miller
Keyword(s):  
Optical Coherence Tomography ◽  
Case Report ◽  
Fluorescein Angiography ◽  
Optic Disc ◽  
Correct Diagnosis ◽  
Optical Coherence ◽  
Vitreous Traction ◽  
Optic Disc Swelling ◽  
Optic Discs

Purpose. The purpose of this study was to report a case of bilateral vitreopapillary traction, previously misdiagnosed as papilledema.Methods. A case report is presented of a 47-year-old woman with a prior diagnosis of papilledema, who is shown to have bilateral vitreopapillary traction rather than true optic disc swelling, confirmed by optical coherence tomography (OCT).Results. OCT showed vitreous traction surrounding the optic discs of both eyes. Fluorescein angiography demonstrated focal leakage of both discs.Conclusion. Bilateral disc elevation caused by vitreous traction can be confused with papilledema. In such cases, OCT can be used to arrive at the correct diagnosis. Although the phenomenon of vitreopapillary traction is well reported, this case indicates that not all ophthalmologists recognize the condition.

scholarly journals Efficacy of oral rifampicin in chronic central serous chorioretinopathy

2018 ◽  
Vol 10 ◽  
pp. 251584141880713 ◽  
Author(s):  
Ramesh Venkatesh ◽  
Manisha Agarwal ◽  
Meha Kantha
Keyword(s):  
Visual Acuity ◽  
Fluorescein Angiography ◽  
Central Serous Chorioretinopathy ◽  
Pigment Epithelium ◽  
Retinal Pigment ◽  
Subretinal Fluid ◽  
Fundus Fluorescein Angiography ◽  
Chronic Central Serous Chorioretinopathy ◽  
Duration Of Symptoms ◽  
Diffuse Retinal Pigment Epitheliopathy

Objective: To evaluate the role of oral rifampicin in the management of chronic central serous chorioretinopathy. Methods: Retrospective analysis of patients diagnosed with chronic central serous chorioretinopathy (duration >3 months) and treated with oral rifampicin 600 mg daily for a maximum period of 3 months was carried out. Baseline visual acuity, fundus fluorescein angiography, and optical coherence tomography were recorded and the patients were followed up. Resolution of subretinal fluid and improvement in visual acuity were the main outcome measures. Recurrence of subretinal fluid was noted. Any adverse reaction to the drug was monitored. Results: Nine eyes of eight patients were included in the study. The average age of the patients was 41.90 years (range 32–52 years). Mean duration of symptoms was 16 months (range 3–60 months). Mean duration of follow-up was 10.11 months (range 3–33 months). Fluorescein angiography showed four eyes with subfoveal leaks and five eyes with diffuse retinal pigment epitheliopathy. Complete resolution of subretinal fluid was achieved in four of the nine eyes – two patients at the end of 1 month, one patient each at the end of 2 and 3 months, respectively. Visual acuity improvement was noted in four of the nine eyes. Three patients had one-line improvement and one patient had a two-line visual improvement. None of the patients had severe adverse events for which the drug had to be discontinued. None of the patients had recurrence of subretinal fluid after the discontinuation of the drug. Conclusion: Oral rifampicin could provide a useful, effective, and cost-effective alternative for treatment of patients with chronic central serous choroidopathy and evidence of healthier retinal pigment epithelium, those with focal leakage. It was not effective in eyes with diffuse retinal pigment epitheliopathy.

scholarly journals Optical Coherence Tomography Angiography of Punctate Inner Choroidopathy

2017 ◽  
Vol 2017 ◽  
pp. 1-3 ◽  
Author(s):  
Blake M. Hampton ◽  
Christopher M. Aderman ◽  
Harry W. Flynn ◽  
Jayanth Sridhar
Keyword(s):  
Optical Coherence Tomography ◽  
Case Report ◽  
Retinal Pigment Epithelium ◽  
Fluorescein Angiography ◽  
Optical Coherence Tomography Angiography ◽  
Pigment Epithelium ◽  
Retinal Pigment ◽  
Subretinal Fluid ◽  
Optical Coherence ◽  
Punctate Inner Choroidopathy

Purpose. To report a case of bilateral choroidal neovascularization (CNV) in punctate inner choroidopathy (PIC) visualized utilizing optical coherence tomography angiography (OCT-A). Methods. Case report. Results. A 29-year-old woman presented with new visual symptoms in both eyes. Fundoscopic exam revealed bilateral multifocal, small, well-defined lesions consistent with PIC. Optical coherence tomography demonstrated subretinal fluid and retinal pigment epithelium detachments (RPEDs) in both eyes. OCT-A revealed bilateral abnormal increased flow within the RPEDs consistent with CNV. Fluorescein angiography confirmed the presence of bilateral CNV. Conclusion. CNV secondary to PIC may be identified using noninvasive optical coherence tomography angiography.

scholarly journals Central Serous Chorioretinopathy Associated with Calcium Channel Blocker Consumption: A Case Report

2021 ◽  
Vol 9 (1) ◽  
pp. 62
Author(s):  
Andi Arus Victor
Keyword(s):  
Optical Coherence Tomography ◽  
Visual Acuity ◽  
Case Report ◽  
Calcium Channel ◽  
Calcium Channel Blocker ◽  
Central Serous Chorioretinopathy ◽  
Channel Blocker ◽  
Inflammatory Drug ◽  
Corrected Visual Acuity ◽  
Best Corrected Visual Acuity

Central serous chorioretinopathy (CSC) is one of the leading causes of blindness in middle-aged population. This case report describes case of CSC associated with amlodipine consumption. A 62-years old woman came with blurry vision on the right eye (RE) for 25 days, prior to admission. Patient was hypertensive and on routine calcium channel blocker (CCB, amlodipine) for the last two months. Initial best corrected visual acuity (BCVA) was 0.3 for her RE and 0.8 on her left eye (0.8). Anterior segment examinations of both eyes were within normal limits. Funduscopy revealed serous retinal detachment on the macula of RE. Optical coherence tomography (OCT) of RE showed subretinal and below choroid fluid accumulation and central macular thickness of 352 µm. Patient was treated with non-steroidal anti-inflammatory drug (NSAID) and vitamins but the complaint worsened. Amlodipine was ceased on the third month of treatment. CSC resolved and final BCVA was 1.0. There might be an association between CCB consumption to incidence of CSC. Our study was the first to describe such occurrence. Further study is required to confirm this association Keywords: Central serous chorioretinopathy, calcium channel blocker, amlodipine, calcium ion, pathogenesis.   Korioretinopati Serosa Sentral Terkait Penggunaan Penghambat Kanal Kalsium: Sebuah Laporan Kasus Abstrak Central serous chorioretinopathy (CSC) merupakan salah satu penyebab utama kebutaan pada populasi usia paruh baya. Laporan kasus ini mendeskripsikan sebuah kasus CSC yang berkaitan dengan konsumsi Amlodipine. Seorang wanita berusia 62 tahun datang dengan keluhan pandangan buram pada mata kanan sejak 25 hari sebelum datang ke Rumah Sakit. Pasien didiagnosis dengan hipertensi dan rutin mengkonsumsi calcium channel blocker (CCB, amlodipine) dalam 2 bulan terakhir. Pemeriksaan tajam visual terbaik / best corrected visual acuity (BCVA) di awal menunjukkan hasil 0.3 pada mata kanan dan 0.8 pada mata kiri. Pemeriksaan anterior segmen pada kedua mata dalam batas normal. Pemeriksaan funduskopi menunjukan ablasio retina serosa pada makula mata kanan. Pemeriksaan optical coherence tomography (OCT) pada mata kanan menunjukkan hasil akumulasi cairan pada subretina dan dibawah koroid, serta ketebalan makula sentral yaitu 352µm. Pasien diberikan tatalaksana berupa non-steroidal anti-inflammatory drug (NSAID) dan vitamin, namun keluhan dirasa memburuk. Konsumsi amlodipine dihentikan pada bulan ke 3. CSC dinyatakan sembuh dengan BCVA akhir 1.0. Terdapat kemungkinan hubungan antara konsumsi CCB dengan insidensi CSC. Studi kami merupakan studi pertama yang mendeskripsikan kejadian tersebut. Dibutuhkan studi lebih lanjut untuk mengkonfirmasi hubungan tersebut. Kata kunci: Korioretinopati serosa sentral, penghambat kanal kalsium, amlodipine, ion kalsium, patogenesis

Cystoid Macular Edema Secondary to Paclitaxel Therapy

2019 ◽  
Vol 2 ◽  
pp. 1 ◽  
Author(s):  
Anibal Martin Folgar ◽  
Jorge Oscar Zarate
Keyword(s):  
Optical Coherence Tomography ◽  
Visual Acuity ◽  
Fluorescein Angiography ◽  
Macular Edema ◽  
Cystoid Macular Edema ◽  
Metastatic Breast ◽  
Breast Adenocarcinoma ◽  
Optical Coherence ◽  
Ophthalmoscopic Examination

We present a 57-year-old referred reduced visual acuity who was in treatment with paclitaxel for developing metastatic breast adenocarcinoma. Ophthalmoscopic examination, optical coherence tomography, and autofluorescence show the cystoid macular edema, but fluorescein angiography is normal, without leakage of dye in the late times. The patient responds well 8 weeks after stopping antineoplastic. Paclitaxel can cause cystoid macular edema and lifting a recovery both anatomical and functional of the macula.

Internal limiting membrane graft as a treatment for the retinal detachment secondary to an optic disc coloboma

2021 ◽  
pp. 112067212199268
Author(s):  
Jorge Fernández-Engroba ◽  
Muhsen Saman ◽  
Jeroni Nadal
Keyword(s):  
Visual Acuity ◽  
Retinal Detachment ◽  
Optic Disc ◽  
Subretinal Fluid ◽  
Visual Outcome ◽  
Internal Limiting Membrane ◽  
Subretinal Space ◽  
Direct Closure ◽  
Retinal Tears ◽  
Optic Disc Coloboma

Purpose: To report our anatomical outcome with the internal limiting membrane (ILM) graft procedure in the management of rhegmatogenous retinal detachment (RRD) secondary to optic disc coloboma (ODC). Methods: Description of a new surgical procedure in one eye of one patient who underwent pars plana vitrectomy (PPV) combined with ILM graft technique. Subsequent follow-up included optical coherence tomography (OCT) and visual acuity. Results: After only 1 week, the OCT revealed the ILM graft plugging the retinal tear with complete resorption of subretinal fluid. The sealing effect of this graft persisted after 6 months. However, visual outcome was poor and corrected distance visual acuity was 20/200 as a result of the previous long-standing retinal detachment with loss of photoreceptors. Conclusion: We suggest that ILM graft could be performed as a first line treatment in the management of RRD secondary to ODC. This direct closure of the retinal tears, allows a quick and effective interruption of the communication between the subretinal space and the vitreous cavity. Detecting these retinal tears and applying this technique as soon as possible could achieve not only an earlier anatomical success but obtain good visual results in retinal tears with RRD secondary to ODC. Further studies will be necessary to provide more evidences

scholarly journals Comparison of Retinal Layer Thickness and Capillary Vessel Density in the Patients with Spontaneously Resolved Acute Central Serous Chorioretinopathy

2020 ◽  
Vol 10 (1) ◽  
pp. 45
Author(s):  
Kyu Jin Han ◽  
Hyeong Ju Kim ◽  
Je Moon Woo ◽  
Jung Kee Min
Keyword(s):  
Visual Acuity ◽  
Layer Thickness ◽  
Central Serous Chorioretinopathy ◽  
Subretinal Fluid ◽  
Vessel Density ◽  
Foveal Avascular Zone ◽  
Retinal Layer ◽  
Healthy Controls ◽  
Retrospective Case ◽  
Capillary Vessel

We investigate retinal layer thickness and capillary vessel density (VD) in the patients with central serous chorioretinopathy (CSC) who recovered spontaneously and evaluate the correlation between the changes in these values and visual outcomes using swept-source optical coherence tomography (SS-OCT) and OCT angiography (OCTA). This retrospective case–control study included 34 eyes of 34 patients with spontaneously resolved acute CSC. The changes in retinal layer thickness and capillary VD were examined using SS-OCT and OCTA after complete resolution of subretinal fluid (SRF). The fellow eyes and 34 healthy eyes were used as controls. In the eyes with CSC, the outer retinal layer was significantly thinner than in the eyes of fellow and healthy controls. The foveal avascular zone area and VDs in the superficial and deep capillary plexus in the eyes with CSC were not significantly different from those in the eyes of fellow and healthy controls. The VD of the choriocapillaris in the eyes with CSC was significantly lower than that in the eyes of fellow and healthy controls. Correlation analyses revealed that the outer retinal layer thickness and initial visual acuity were positively correlated with the final visual acuity. Furthermore, the initial SRF area and height were negatively correlated with the outer retinal layer thickness after SRF resolution. Attenuation of outer retinal layer thickness and decreased VD of the choriocapillaris were observed in the eyes with spontaneously resolved acute CSC. The outer retinal layer thickness could be an important visual predictor of CSC.

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