scholarly journals MOLECULAR COMPLEXES OF GERMANIUM TETRACHLORIDE WITH NIACIN, NICOTINIC AMIDE, ISONICOTINIC HYDRAZIDE AND THEIR PHARMACOLOGICAL ACTIONS

2016 ◽  
Vol 21 (2(58)) ◽  
pp. 18 ◽  
Author(s):  
I. I. Seifullina ◽  
E. E. Martsinko ◽  
N. M. Khristova ◽  
E. A. Chebanenko
Keyword(s):  
Molecular Complexes ◽  
Germanium Tetrachloride ◽  
Isonicotinic Hydrazide

Probing massive cold cores discovered by ISO in quiescent galactic molecular complexes

2002 ◽  
Vol 4 ◽  
pp. 133-133
Author(s):  
D. Teyssier ◽  
P. Hennebelle ◽  
M. Pérault
Keyword(s):  
Molecular Complexes

Solid State Analysis and Theoretical Explorations on Polymorphic and Hydrate Forms of p-Hydroxybenzaldehyde Isonicotinichydrazone: Effect of Additives on Polymorphic Crystallization

2018 ◽  
Author(s):  
Lincy Tom ◽  
Victoria A. Smolenski ◽  
Jerry P. Jasinski ◽  
M.R. Prathapachandra Kurup
Keyword(s):  
Hirshfeld Surface ◽  
Framework Analysis ◽  
Reaction Conditions ◽  
Space Groups ◽  
Effect Of Additives ◽  
Ft Ir ◽  
Packing Arrangement ◽  
The Stability ◽  
Ir And Raman ◽  
Isonicotinic Hydrazide

The reaction of p-hydroxybenzaldehyde with an equimolar amount of isonicotinic hydrazide afforded two polymorphic and hydrate forms of p-hydroxybenzaldehyde isonicotinichydrazone (HBIH) by varying the experimental reaction conditions. The compounds are fully characterized by means of single crystal and powder diffraction methods, vibrational spectroscopy (FT-IR and Raman), thermal and elemental analysis. The compound crystallizes in three different forms in two different space groups, P21/c (form PA and PB) and Pbca (PC). The Hirshfeld surface analysis shows the differences in the relative contributions of intermolecular interactions to the total Hirshfeld surface area for the HBIH molecules. The calculated pairwise interaction energies (104-116 kJ/mol) can be related to the stability of the crystals. Energy framework analysis identifies the interaction hierarchy and their topology. The geometry and conformation of the three forms are essentially similar which differ only by packing arrangement.

Solid State Analysis and Theoretical Explorations on Polymorphic and Hydrate Forms of p-Hydroxybenzaldehyde Isonicotinichydrazone: Effect of Additives on Polymorphic Crystallization

2018 ◽  
Author(s):  
Lincy Tom ◽  
Victoria A. Smolenski ◽  
Jerry P. Jasinski ◽  
M.R. Prathapachandra Kurup
Keyword(s):  
Hirshfeld Surface ◽  
Framework Analysis ◽  
Reaction Conditions ◽  
Space Groups ◽  
Effect Of Additives ◽  
Ft Ir ◽  
Packing Arrangement ◽  
The Stability ◽  
Ir And Raman ◽  
Isonicotinic Hydrazide

The reaction of p-hydroxybenzaldehyde with an equimolar amount of isonicotinic hydrazide afforded two polymorphic and hydrate forms of p-hydroxybenzaldehyde isonicotinichydrazone (HBIH) by varying the experimental reaction conditions. The compounds are fully characterized by means of single crystal and powder diffraction methods, vibrational spectroscopy (FT-IR and Raman), thermal and elemental analysis. The compound crystallizes in three different forms in two different space groups, P21/c (form PA and PB) and Pbca (PC). The Hirshfeld surface analysis shows the differences in the relative contributions of intermolecular interactions to the total Hirshfeld surface area for the HBIH molecules. The calculated pairwise interaction energies (104-116 kJ/mol) can be related to the stability of the crystals. Energy framework analysis identifies the interaction hierarchy and their topology. The geometry and conformation of the three forms are essentially similar which differ only by packing arrangement.

Influence of β-Cyclodextrin and Hydroxypropyl-β-Cyclodextrin on Enhancement of Solubility and Dissolution of Isradipine

2017 ◽  
Vol 10 (3) ◽  
pp. 3752-3757
Author(s):  
Narendar D ◽  
Ettireddy S
Keyword(s):  
Inclusion Complex ◽  
Dissolution Rate ◽  
Solid Dispersions ◽  
Physical Stability ◽  
Molecular Complexes ◽  
In Vitro Dissolution ◽  
Molar Ratio ◽  
Phase Solubility ◽  
Cyclodextrin Complexation

The content of this investigation was to study the influence of β-cyclodextrin and hydroxy propyl-β-cyclodextrin complexation on enhancement of solubility and dissolution rate of isradipine. Based on preliminary phase solubility studies, solid complexes prepared by freeze drying method in 1:1 molar ratio were selected and characterized by DSC for confirmation of complex formation. Prepared solid dispersions were evaluated for drug content, solubility and in vitro dissolution. The physical stability of optimized formulation was studied at refrigerated and room temperature for 2 months. Solid state characterization of optimized complex performed by DSC and XRD studies.  Dissolution rate of isradipine was increased compared with pure drug and more with HP-β-CD inclusion complex than β-CD. DSC and XRD analyzes that drug was in amorphous form, when the drug was incorporated as isradipine β-CD and HP-β-CD inclusion complex. Stability studies resulted in low or no variations in the percentage of complexation efficiency suggesting good stability of molecular complexes. The results conclusively demonstrated that the enhancement of solubility and dissolution rate of isradipine by drug-cyclodextrin complexation was achieved.   

Molecular Complexes of Monoammonium Glycyrrhizinate with Alphahederin and Hederasaponin C

2015 ◽  
Vol 12 (2) ◽  
pp. 109-114 ◽  
Author(s):  
Leonid A. Yakovishin ◽  
Vladimir I. Grishkovets ◽  
Elena N. Korzh
Keyword(s):  
Molecular Complexes ◽  
Hederasaponin C

scholarly journals Optical soliton molecular complexes in a passively mode-locked fibre laser

2019 ◽  
Vol 10 (1) ◽  
Author(s):  
Z. Q. Wang ◽  
K. Nithyanandan ◽  
A. Coillet ◽  
P. Tchofo-Dinda ◽  
Ph. Grelu
Keyword(s):  
Molecular Complexes ◽  
Optical Soliton ◽  
Fibre Laser

The effect of terminal N-donor aromatic ligands on sensitization and emission of lanthanide ions in Zn2Ln (Ln = Eu, Tb) complexes with 4-biphenylcarboxylate anions

2021 ◽  
Author(s):  
Stanislav N. Melnikov ◽  
Igor Evstifeev ◽  
Stanislav A. Nikolaevskii ◽  
Ivan V. Ananyev ◽  
Evgenia Varaksina ◽  
...  
Keyword(s):  
General Formula ◽  
Molecular Complexes ◽  
Lanthanide Ions ◽  
Biphenylcarboxylic Acid

The systematical series of Zn-Ln trinuclear carboxylate molecular complexes with general formula [Zn2Ln(NO3)(phbz)6(L)2] (Ln = Eu, Gd, Tb; phbz is anion of 4-biphenylcarboxylic acid; L is pyridine, 2,3-lutidine or 2,2’-bipyridine)...

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