scholarly journals Sleep in lonely heroin-dependent patients receiving methadone maintenance treatment: longer sleep latency, shorter sleep duration, lower sleep efficiency, and poorer sleep quality

Oncotarget ◽  
2017 ◽  
Vol 8 (51) ◽  
pp. 89278-89283 ◽  
Author(s):  
Hong-Jie Li ◽  
Bao-Liang Zhong ◽  
Yan-Min Xu ◽  
Jun-Hong Zhu ◽  
Jin Lu
2012 ◽  
Vol 24 (6) ◽  
pp. 356-360 ◽  
Author(s):  
Wen-Yu Hsu ◽  
Nan-Ying Chiu ◽  
Jui-Ting Liu ◽  
Chieh-Hui Wang ◽  
Ting-Gang Chang ◽  
...  

Hsu W-Y, Chiu N-Y, Liu J-T, Wang C-H, Chang T-G, Liao Y-C, Kuo P-I. Sleep quality in heroin addicts under methadone maintenance treatment.Background: Sleep disturbance is a common phenomenon among opiate addicts. The side effects of opiate addiction or opiate withdrawal might result in sleep disturbance. However, their problems might be related to sedative medication abuse, alcohol abuse or heroin relapse. Sleep is an important issue in this population.Objective: To evaluate the prevalence of sleep disorders in heroin addicts receiving methadone maintenance treatment (MMT) and analyse the correlation between related factors, such as age at opiate exposure, opiate exposure duration, duration in MMT, methadone current dosage, methadone attendance rate and the severity of sleep disorders.Method: We enrolled 121 heroin addicts who were receiving MMT. We collected data on the duration of insomnia, hypnotic history, Visual Analogue Scale-10 of sleep quality, Pittsburgh Sleep Quality Index (PSQI), methadone dosage, methadone history and opiate history.Results: The mean of the PSQI was 9.1 ± 5.4, and 70.2% of patients had PSQI scores >5, indicating they were poor sleepers. We also found the PSQI scores were correlated significantly with the methadone dosage.Conclusions: The sleep disturbance prevalence rate of opiate addicts under MMT was high in Taiwan, as shown in the previous studies, and the severity of sleep disturbance has been underestimated.


Nutrients ◽  
2021 ◽  
Vol 13 (10) ◽  
pp. 3489
Author(s):  
Mara McStay ◽  
Kelsey Gabel ◽  
Sofia Cienfuegos ◽  
Mark Ezpeleta ◽  
Shuhao Lin ◽  
...  

This review examines the effects of two popular intermittent fasting regimens on sleep in adults with overweight and obesity. Specifically, the effects of time restricted eating (TRE; eating all food within a 4–10 h window) and alternate day fasting (ADF; 600 kcal fast day alternated with ad libitum feast day) on sleep quality, sleep duration, sleep latency, sleep efficiency, insomnia severity, and risk of obstructive sleep apnea, will be summarized. The role of weight loss will also be discussed. Results from our review reveal that the majority of these trials produced weight loss in the range of 1–6% from baseline. Sleep quality and sleep duration remained unaltered with TRE and ADF, as assessed by the Pittsburgh Sleep Quality Index (PSQI). The effects of intermittent fasting on sleep latency and sleep efficiency are mixed, with one study showing worsening of these parameters, and others showing no effect. Insomnia severity and the risk of obstructive sleep apnea remained unchanged in the trials assessing these metrics. Taken together, these preliminary findings suggest that TRE and ADF produce mild to moderate weight loss (1–6%) but their effects on sleep remain unclear. Solid conclusions are difficult to establish since participants in the studies had healthy sleep durations and no clinical insomnia at baseline, leaving little room for improvement in these metrics. Moreover, none of the trials were adequately powered to detect statistically significant changes in any measure of sleep. Future well-powered trials, conducted in individuals with diagnosed sleep disturbances, will be necessary to elucidate the effect of these popular diets on sleep.


2010 ◽  
Vol 45 (9) ◽  
pp. 1431-1434 ◽  
Author(s):  
Adrien Charpentier ◽  
Sebastien Bisac ◽  
Isabelle Poirot ◽  
Jean Vignau ◽  
Olivier Cottencin

2020 ◽  
Author(s):  
Penghui Cao ◽  
Zhaohua Zhang ◽  
Jun Zhong ◽  
Shichao Xu ◽  
Qiaofang Huang ◽  
...  

Abstract Background: Anxiety, a major factor that affects the therapeutic effect and dropout rate of methadone maintenance treatment, has a high prevalence among MMT users. This study aims to investigate the prevalence of anxiety in MMT users and explore the main influencing factors of anxiety of methadone maintenance treatment users.Methods: 177 methadone maintenance treatment users in Guangzhou, China were evaluated. The socio-demographic, duration and MMT-related characteristics were documented. Anxiety, quality of life and sleep quality were evaluated by Beck Anxiety inventory (BAI), the Quality of Life-Drug Addiction (QOL-DA) and Pittsburgh Sleep Quality Index (PSQI) respectively. The correlation between different factors and BAI score was also analyzed.Results: The BAI total score, QOL-DA score, PSQI score were 7.1±8.2, 163.5±21.4, 6.0±4.0 respectively. 30.5% of the subjects showed mild to severe anxiety. Treatment interruption, QOL-DA score and PSQI score had strong correlations with the score of BAI, with correlation coefficients of 0.17, -0.08 and 0.50 respectively.Conclusions: Anxiety symptoms were commonly presented in MMT users. Treatment interruption, quality of life and sleep quality are the major factors affecting anxiety of MMT users.


Author(s):  
Ali Kheradmand ◽  
Zahra Amini Ranjbar ◽  
Zahra Zeynali ◽  
Abdol Reza Sabahy ◽  
Nouzar Nakhaee

MedPharmRes ◽  
2018 ◽  
Vol 2 (4) ◽  
pp. 7-14
Author(s):  
Kien To ◽  
Anh Huynh ◽  
Vi Vu ◽  
Hoang Vu ◽  
Trung Nguyen ◽  
...  

Introduction: Continuing Medical Education (CME) significantly improves the competency of healthcare workers in Methadone Maintenance Treatment (MMT) clinics. However, CME courses are very costly, and a few participants fully attended a course. Online training is an alternative approach to efficiently improve training outcomes. The study assessed needs and possibility of online training courses of MMT clinics in southern Vietnam. Methods: A google form was designed to collect characteristics, man-powers, facilities, online activities and training needs of MMT clinics. E-mails were sent to all MMT clinics in southern Vietnam to ask for their participants. A representative of MMT clinics who satisfied the inclusion invited to complete the form. Result: 93 MMT clinics completed the survey. The response rate was 62% (93/150). One MMT clinic had 3 doctors/assistant doctors, 3 pharmacists/drug dispensers, 2 consultants and 3 other professionals on average. The number of clients visiting the clinic in the last month was 150. About 94% (93/95) of MMT clinics provide other additional services. On average, 385 clients came to MMT for other services. All clinics had adequate devices for online and blended training. Conclusion: MMT clinics had high training needs and were willing to attend online and blended training courses. Online and blended training were possible in MMT clinics.


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