Approaches to Solving Specific Safety Issues in the Territory of Murska Sobota Police Directorate

Radiotherapy has unquestionable benefits, but it is also associated with unique and specific safety issues. It is the only application of radiation in which humans are intentionally delivered very high doses. Safety in radiotherapy remains heavily dependent on human actions. A step-by-step approach is suggested for the prevention of accidental exposures in radiation therapy: (1) allocation of responsibilities to qualified professionals, and design of a quality and safety programme - no radiotherapy practice should be operated without these key elements; (2) use of the lessons from accidental exposures to test whether the quality and safety programme is sufficiently robust against these types of events –publications by the International Commission on Radiological Protection (ICRP) and the International Atomic Energy Agency provide a collection of lessons to facilitate this step; and (3) find other latent risks by posing the questions ‘What else could go wrong?’ or ‘What other potential hazards might be present?’ in a systematic, anticipative manner - methods to do so are described briefly in ICRP Publication 112.

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Identification and Prioritization of Generic Nuclear Safety Problems Requiring CFD Analysis

Volume 5: Fuel Cycle and High and Low Level Waste Management and Decommissioning; Computational Fluid Dynamics (CFD), Neutronics Methods and Coupled Codes; Instrumentation and Control ◽

10.1115/icone17-75482 ◽

2009 ◽

Cited By ~ 2

Author(s):

Brian L. Smith

Keyword(s):

Single Phase ◽

Safety Issues ◽

Group A ◽

Computational Fluid Dynamics Cfd ◽

Specific Safety ◽

Multi Phase ◽

High Cycle Thermal Fatigue ◽

Specific Concern ◽

Country Specific

Within the framework of the activities and responsibilities of the OECD/NEA/WGAMA group, a modest PIRT-type exercise was initiated to identify and prioritize country-specific safety issues for which it was considered that analysis using Computational Fluid Dynamics (CFD) could bring real benefits in regard to improved safety. Conventional PIRT procedures were followed as far as possible: the problem scope and objectives of the exercise were first defined, and then a panel of experts was assembled to identify and prioritize the safety items of specific concern to the country represented. Collating the information received, it was possible to identify those safety issues which were clearly country-specific in origin, and those which were of generic interest for which a common approach to benchmarking would be justified. Separate lists were compiled for single-phase and multi-phase phenomena. The paper summarizes the procedures undertaken, lists and prioritizes the safety topics identified in the study, and presents the final ranking in terms of generic importance. Also described are perspectives for a first follow-up activity: the promotion of a new validation benchmark activity based on the problem of high-cycle thermal fatigue in mixing tees.

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Using network screening methods to determine locations with specific safety issues: A design consistency case study

Accident Analysis & Prevention ◽

10.1016/j.aap.2017.06.006 ◽

2017 ◽

Vol 106 ◽

pp. 223-233 ◽

Cited By ~ 1

Author(s):

Andrew J. Butsick ◽

Jonathan S. Wood ◽

Paul P. Jovanis

Keyword(s):

Screening Methods ◽

Safety Issues ◽

Network Screening ◽

Specific Safety ◽

Design Consistency

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Specialized therapeutic approaches

10.1093/med/9780198738756.003.0008 ◽

2018 ◽

Author(s):

Brogan Foster ◽

Paul A. Brogan

Keyword(s):

Dose Calculation ◽

Paediatric Rheumatology ◽

Haematopoietic Stem Cell ◽

Joint Injection ◽

Biologic Therapies ◽

Therapeutic Approaches ◽

Safety Issues ◽

Paediatric Practice ◽

The Subject ◽

Specific Safety

This chapter provides updated guidance on specialized therapeutic approaches relevant to paediatric rheumatology. Detailed overviews include: intra-articular injections including guidance on triamcinolone hexacetonide and dose for paediatric joint injection; current indications and recommended doses for biologic therapies, including updated summaries of regulatory approvals for the use of these treatments; an overview of medicines commonly used in paediatric rheumatology, including a commentary on paediatric pharmacokinetics and specific safety issues; dose calculation in paediatric practice; and practical advice when considering different medicine formulations in paediatric practice. An important feature of the second edition is a fully updated section on haematopoietic stem cell transplantation for autoimmune and autoinflammatory diseases, providing a comprehensive and up-to-date overview of the subject.

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Biologics in paediatric rheumatic diseases

Oxford Textbook of Rheumatology ◽

10.1093/med/9780199642489.003.0084_update_003 ◽

2013 ◽

pp. 650-656

Author(s):

Daniel J. Lovell ◽

Nicolino Ruperto ◽

Hermine I. Brunner ◽

Alberto Martini

Keyword(s):

Juvenile Idiopathic Arthritis ◽

Rheumatic Diseases ◽

Treatment Guidelines ◽

Chronic Arthritis ◽

Treatment Goals ◽

Biological Therapies ◽

Biologic Therapies ◽

Safety Issues ◽

Specific Safety ◽

Paediatric Rheumatic Diseases

The introduction of biological therapies into the treatment of children with rheumatic diseases has dramatically changed our expectation about treatment goals in children with a wide variety of forms of chronic arthritis. The outcomes of these children have been dramatically improved. The application of biological therapies to other paediatric rheumatic diseases has been much more limited and a change in treatment of these other rheumatic diseases has been less impacted by the introduction of biological therapies. The overall safety profile of biological therapies in children reveal issues that are similar to those in adults both in the frequency and types of toxicities. The paediatric-specific safety issues are childhood vaccinations and varicella. Biologic therapies have been included in recently developed validated treatment guidelines for juvenile idiopathic arthritis (JIA). Biologic therapies for children with rheumatic diseases have advanced greatly in the last decade and many exciting studies are ongoing and in development.

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Biologics in paediatric rheumatic diseases

10.1093/med/9780199642489.003.0084 ◽

2013 ◽

Author(s):

Daniel J. Lovell ◽

Nicolino Ruperto ◽

Hermine I. Brunner ◽

Alberto Martini

Keyword(s):

Juvenile Idiopathic Arthritis ◽

Rheumatic Diseases ◽

Treatment Guidelines ◽

Chronic Arthritis ◽

Treatment Goals ◽

Biological Therapies ◽

Biologic Therapies ◽

Safety Issues ◽

Specific Safety ◽

Paediatric Rheumatic Diseases

The introduction of biological therapies into the treatment of children with rheumatic diseases has dramatically changed our expectation about treatment goals in children with a wide variety of forms of chronic arthritis. The outcomes of these children have been dramatically improved. The application of biological therapies to other paediatric rheumatic diseases has been much more limited and a change in treatment of these other rheumatic diseases has been less impacted by the introduction of biological therapies. The overall safety profile of biological therapies in children reveal issues that are similar to those in adults both in the frequency and types of toxicities. The paediatric-specific safety issues are childhood vaccinations and varicella. Biologic therapies have been included in recently developed validated treatment guidelines for juvenile idiopathic arthritis (JIA). Biologic therapies for children with rheumatic diseases have advanced greatly in the last decade and many exciting studies are ongoing and in development.

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What Events Precede Violent Incidents in Psychiatric Hospitals?

The British Journal of Psychiatry ◽

10.1192/bjp.165.1.107 ◽

1994 ◽

Vol 165 (1) ◽

pp. 107-112 ◽

Cited By ~ 92

Author(s):

Georgia Powell ◽

Woody Caan ◽

Michael Crowe

Keyword(s):

Mental Health ◽

Staff Training ◽

Relative Frequency ◽

Health And Safety ◽

Psychiatric Hospitals ◽

Safety Issues ◽

Staff Members ◽

Mental Health Act ◽

Self Harm ◽

Specific Safety

BackgroundThe study aimed to identify, classify and measure the relative frequency of events preceding violent incidents in psychiatric hospitals.MethodPossible antecedents for 1000 incidents in three associated psychiatric hospitals over 13 months were investigated with an ‘untoward incident database’.ResultsFrom eyewitness accounts, 921 incidents (92%) could be related to one of 15 categories of antecedent involving characteristics of the patient, or of the hospital regime, or interactions with other individuals. Overall, the most common antecedents involved patients who were generally agitated or disturbed (286), restrictions on patients associated with the routine hospital regime (192) or provocation by other patients, relatives or visitors (175). Incidents arising from staff members initiating contact with patients were very rare (7). Twenty-one patients were involved in 10 or more incidents, including 19 (90%) who were detained under the Mental Health Act. These patients were more likely to commit assaults after certain antecedents (self-harm, absconding or arson) which were serious incidents in themselves.ConclusionsStaff training on specific safety issues will be needed under the new Management of Health and Safety at Work Regulations.

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