scholarly journals ACTUAL ISSUES OF MODERN EPIDEMIOLOGY OF MELIOIDOSIS: A LITERATURE REVIEW AND ANALYSIS OF IMPORTED CASES TO NON-ENDEMIC REGIONS

Author(s):  
Irina B. Zakharova

Introduction. Melioidosis is a severe infection disease with the high mortality rate due to saprophytic bacterium Burkholderia pseudomallei. For the time present, the area of the distribution of the pathogen is much wider than in the case of the traditionally endemic Southeast Asia and Northern Australia and covers the humid tropics and subtropics of all continents. Methods. The search for data and analysis of disease cases in non-endemic areas for the period from 2003 to April 2017. Results. Over the past 15 years, 120 cases of melioidosis in non-endemic countries were described, that is 5,5 times higher than in the same previous period. There is no direct dependence of infection probability on the age and risk factors, but the presence of diabetes or chronic diseases doubles the risk of a fatal outcome of melioidosis. Southeast Asia still prevails as the origin of infection (62.5% of cases), however, the number of imported cases of melioidosis from Mexico, the Caribbean, South America, East Africa, Madagascar, China and the Pacific region begins to increase.

Author(s):  
Irina B. Zakharova

Introduction. Melioidosis is a severe infection disease with the high mortality rate due to saprophytic bacterium Burkholderia pseudomallei. For the time present, the area of the distribution of the pathogen is much wider than in the case of the traditionally endemic Southeast Asia and Northern Australia and covers the humid tropics and subtropics of all continents. Methods. The search for data and analysis of disease cases in non-endemic areas for the period from 2003 to April 2017. Results. Over the past 15 years, 120 cases of melioidosis in non-endemic countries were described, that is 5,5 times higher than in the same previous period. There is no direct dependence of infection probability on the age and risk factors, but the presence of diabetes or chronic diseases doubles the risk of a fatal outcome of melioidosis. Southeast Asia still prevails as the origin of infection (62.5% of cases), however, the number of imported cases of melioidosis from Mexico, the Caribbean, South America, East Africa, Madagascar, China and the Pacific region begins to increase.


2008 ◽  
Vol 15 (5) ◽  
pp. 237-239 ◽  
Author(s):  
Dimas Mateos Corral ◽  
Allan L Coates ◽  
Yvonne CW Yau ◽  
Raymond Tellier ◽  
Mindy Glass ◽  
...  

Burkholderia pseudomalleiis a pathogen identified with increasing frequency in the respiratory tracts of cystic fibrosis (CF) patients from endemic areas such as Southeast Asia and northern Australia. The following report describes the first known reported case in a CF patient from the Caribbean attending a North American CF clinic.


2021 ◽  
Author(s):  
Aaron Shiels

Abstract The Pacific rat, R. exulans, is an major agricultural and environmental pest in parts of Southeast Asia and the Pacific. Thought to have spread with Polynesian colonists over the past several thousand years, it is now found through much of the Pacific basin, and is extensively distributed in the tropical Pacific. It poses a significant threat to indigenous wildlife, particularly ground-nesting birds, and has been linked to the extinction of several bird species. R. exulans may also transmit diseases to humans.


2009 ◽  
Vol 30 (5) ◽  
pp. 195
Author(s):  
Bart J Currie

There are 25-50 human cases of melioidosis annually in Australia. While the vast majority occur in the tropical north, sporadic cases have been documented from unexpected temperate locations and, each year, several cases are diagnosed in southern hospitals in patients infected in and returned or travelling from northern Australia or southeast Asia.


2004 ◽  
Vol 48 (5) ◽  
pp. 1763-1765 ◽  
Author(s):  
Allen C. Cheng ◽  
Dale A. Fisher ◽  
Nicholas M. Anstey ◽  
Dianne P. Stephens ◽  
Susan P. Jacups ◽  
...  

ABSTRACT Melioidosis, an infection due to Burkholderia pseudomallei, is endemic in southeast Asia and northern Australia. We reviewed our experience with meropenem in the treatment of severe melioidosis in 63 patients over a 6-year period. Outcomes were similar to those of ceftazidime-treated patients (n = 153) despite a deliberate selection bias to more-unwell patients receiving meropenem. The mortality among meropenem-treated patients was 19%. One patient had a possible drug fever associated with the use of meropenem. We conclude that meropenem (1 g or 25 mg/kg every 8 h intravenously for ≥14 days) is an alternative to ceftazidime and imipenem in the treatment of melioidosis. The use of meropenem may be associated with improved outcomes in patients with severe sepsis associated with melioidosis.


2015 ◽  
Vol 144 (6) ◽  
pp. 1330-1337 ◽  
Author(s):  
B. MELOT ◽  
J. COLOT ◽  
F. LACASSIN ◽  
S. TARDIEU ◽  
E. LAPISARDI ◽  
...  

SUMMARYMelioidosis is an infectious disease caused byBurkholderia pseudomallei, a bacterium endemic in Southeast Asia and northern Australia. In New Caledonia, sporadic cases were first described in 2005; since then, more cases have been identified. To improve our understanding of melioidosis epidemiology in New Caledonia, we compared the local cases andB. pseudomalleiisolates with those from endemic areas. Nineteen melioidosis cases have been diagnosed in New Caledonia since 1999, mostly severe and with frequent bacteraemia, leading to three (16%) fatalities. All but one occurred in the North Province. Besides sporadic cases caused by non-clonal strains, we also identified a hotspot of transmission related to a clonal group ofB. pseudomalleithat is phylogenetically related to Australian strains.


Itinerario ◽  
1978 ◽  
Vol 2 (1) ◽  
pp. 47-48
Author(s):  
Gerard Nagelkerke

The Royal Institute of Linguistics and Anthropology of Leyden which was founded in 1851, has as objective ‘Furthering the study of the languages, geography, ethnology and history of Southeast Asia, the Pacific and the Caribbean and adjacent areas’ (article II of the Institute's statutes, 1976). This objective it tries to achieve through:a. the establishment, maintenance and extension of the necessary scientific and administrative apparatus, in particular the library and other scientific departments;b. the publication of a journal entitled Bijdragen tot de taal-, land- en volkenkunde, and other works;c. the stimulation of scientific research, particularly in consultation with the Minister of Education and Science;d. the maintenance of relations with other scientific organisations and institutions, inter alia through an exchange of publications.


Author(s):  
Takashi Terada

This chapter aims to provide a fresh interpretation of Japan’s patterned approach to the Association of Southeast Asian Nations (ASEAN) over the past forty years, examining it in the context of Japan’s interest in leading wider concepts of regional institutions in Asia and the Pacific. It analyzes Japan’s policy direction and diplomatic efforts to maintain good relations with ASEAN as a key precondition for its commitment to establishing six different regional initiatives or institutions beyond Southeast Asia, representing a view that Japan has promoted its ASEAN policy in parallel with its commitment to wider regional institutions. Based on the analytical presumptions promoted by neoclassical realism, this chapter pursues Japanese policy responses to the international/regional structural changes through examining, especially, Japanese prime ministers’ perceptions, ideas, and roles to identify Japan’s distinctive moves on ASEAN and wider regional institutions: the end of the Vietnam War for ASEAN, the Plaza Accord and regional economic interdependence for APEC, the AFC for APT, China’s charm offensive diplomacy for EAS, China’s hegemonic rise for TPP, and Japan-China competition over economic rules for FOIP. Japan has acknowledged the solidarity and integration of ASEAN as a prerequisite for the effective development of these wider regional institutions, making it a significant task for Japan to ease ASEAN’s concern about its possible marginalization within Asia a politics and economics.


2019 ◽  
Vol 12 (5) ◽  
pp. e228856 ◽  
Author(s):  
Clément Auvens ◽  
Catherine Neuwirth ◽  
Lionel Piroth ◽  
Mathieu Blot

Melioidosis is a protean disease which is endemic to Southeast Asia and northern Australia. Here, we report a case of infected aortic aneurysm due to Burkholderia pseudomallei in an immunocompetent man 6 months after a trip to northern Malaysia. This patient initially received inappropriate surgical and antibiotic treatment, leading to a peri-prosthetic aortic infection with lumbar spondylitis and contiguous psoas muscle abscess. This case highlights the difficulty of diagnosing melioidosis given its diverse clinical manifestations and the limits of routine microbiological methods to identify B. pseudomallei. Melioidosis should be considered a possible diagnosis in individuals with unexplained fever subsequent to travel in an endemic area.


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