According to the gas explosion theory and the investigation of occurred gas explosion, the basic events that lead to coal mine gas explosion are summarized and the fault tree is worked out. Besides, the fault tree analysis is used for qualitative analysis. The minimal cuts sets, minimal path sets and structure importance are solved. Accordingly, the reasons of gas explosion are obtained, which can provide references for the prevention of coal mine gas explosion. The study showed that: the minimal cut sets of gas explosion is much(165) and the minimal path sets is small(4), and it is the major dangerous and harmful factors in coal mine. It that gas concentration must be strictly controlled and all sources of ignition should be eliminated is the basic and fundamental way to prevent mine gas explosion.