Professional Oral Hygiene as a Therapeutic Option for Pediatric Patients With Plasma Cell Gingivitis: Preliminary Results of a Prospective Case Series

2011 ◽  
Vol 82 (12) ◽  
pp. 1670-1675 ◽  
Author(s):  
Paolo G. Arduino ◽  
Francesco D'Aiuto ◽  
Claudio Cavallito ◽  
Paola Carcieri ◽  
Mario Carbone ◽  
...  
Keyword(s):  
Plasma Cell ◽  
Oral Hygiene ◽  
Pediatric Patients ◽  
Therapeutic Option ◽  
Case Series ◽  
Preliminary Results ◽  
Prospective Case Series

Treatment of Mycoplasma pneumoniae-Induced Rash and Mucositis With Cyclosporine

2019 ◽  
Vol 23 (6) ◽  
pp. 608-612 ◽  
Author(s):  
Heidi Oi-Yee Li ◽  
Sophia Colantonio ◽  
Michele L. Ramien
Keyword(s):  
Mycoplasma Pneumoniae ◽  
Pediatric Patients ◽  
Therapeutic Option ◽  
Case Series ◽  
Supportive Therapy ◽  
Standards Of Care ◽  
Prodromal Symptoms ◽  
Potential Efficacy ◽  
Effective Therapeutic Option ◽  
Evidence Based Guidelines

Background Mycoplasma pneumoniae-induced rash and mucositis (MIRM) is a relatively newly recognized clinical entity that typically presents with predominant mucositis accompanied by variable cutaneous involvement 7-9 days after the onset of prodromal symptoms. There are no evidence-based guidelines for treatment, and current standards of care may include supportive therapy, antibiotics, corticosteroids, and intravenous immunoglobulin . Objective This case series aims to describe the potential efficacy of cyclosporine A (CsA) in the treatment of MIRM. Methods The present case series details our use of CsA early in the course of MIRM in 3 pediatric patients. Results Rapid clinical resolution was observed following CsA therapy. Conclusions We suggest that early initiation of CsA may be an effective therapeutic option for MIRM.

scholarly journals Oral Propranolol Therapy for Benign Capillary Hemangiomas in a Series of Adult and Pediatric Patients

2018 ◽  
Vol 32 (2) ◽  
pp. 34-37
Author(s):  
Gerardo Aniano C. Dimaguila ◽  
Emmanuel S. Samson
Keyword(s):  
Head And Neck ◽  
Pediatric Patients ◽  
Case Series ◽  
Lesion Size ◽  
Capillary Hemangioma ◽  
Clinical Resolution ◽  
Prospective Case Series ◽  
The Right ◽  
Propranolol Therapy ◽  
Oral Propranolol

Objective: To describe outcomes of oral propranolol therapy in a series of adult and pediatric patients diagnosed with benign capillary hemangioma of the head and neck. Methods:             Design:           Prospective Case Series             Setting:           Tertiary Government Hospital Participants: Ten (10) patients representing all patients clinically diagnosed with benign capillary hemangioma of the head and neck, enrolled in the study from 2012 to 2015. Results: Two (2) adults and eight (8) children were enrolled in the study. Although a decrease in lesion size was observed in half of the participants starting at three months, only one (1) attained complete resolution of the lesion-- a 12-year-old girl with hemangioma of the right parotid gland that attained clinical resolution of symptoms after four months of treatment. The remaining nine out of ten (9/10) participants did not attain complete clinical resolution; but there was a decrease in lesion size in four (4) of these participants. For the remaining five (5) participants, there was neither a decrease nor an increase in lesion size. Altogether, of the two adult participants, only one responded to therapy, while only 4 out of 8 pediatric participants responded to therapy. There were no noticeable differences between adult and pediatric patients in terms of resolution and plateau. Aside from mild bradycardia expected with propranolol, no adverse reactions were observed during the course of treatment. Conclusion: Although half of our participants responded to oral propranolol therapy, whether these observations may be attributable to oral propranolol alone cannot be concluded. Keywords: hemangioma, capillary; hemangioma; propranolol administration, oral; propranolol

OCTA-guided navigated laser therapy for advanced macula neovascularization secondary to age related macular degeneration

2020 ◽  
pp. 112067212098319
Author(s):  
Francesca Amoroso ◽  
Eric H Souied ◽  
Salomon Yves Cohen ◽  
Alexandre Pedinielli ◽  
Polina Astroz ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Macular Degeneration ◽  
Optical Coherence Tomography Angiography ◽  
Therapeutic Option ◽  
Case Series ◽  
Age Related Macular Degeneration ◽  
Optical Coherence ◽  
Age Related ◽  
Prospective Case Series

Introduction: To evaluate the effects of the Navilas system guided by optical coherence tomography angiography for advanced macular neovascularization (MNV) secondary to age-related macular degeneration (AMD). Methods: Prospective case-series including nine eyes presenting with advanced MNV with persistence of exudative signs, no longer responding to anti-VEGF therapy, best-corrected visual acuity at least of 1.3 logMar. All patients were treated with Navilas guided by overlaid optical coherence tomography angiography (OCTA) images at the site of branching large neovascular trunks. Results: Occlusion of large neovascular trunks successfully occurred in all nine included patients. OCTA analysis revealed, at 1 month follow up, MNV total area decreasing from 6.2 ± 3.1 to 2.6 ± 3.4 mm2. At 6 months follow up, mean MNV area was 3.3 ± 3.4 mm2 ( p = 0.008). Conclusion: This preliminary study showed that Navilas treatment guided by OCTA may represent an attractive therapeutic option in advanced neovascular lesions secondary to AMD.

Transoral Laser Microsurgery for Untreated Glottic Carcinoma

2007 ◽  
Vol 137 (3) ◽  
pp. 482-486 ◽  
Author(s):  
David G. Grant ◽  
John R. Salassa ◽  
Michael L. Hinni ◽  
Bruce W. Pearson ◽  
Richard E. Hayden ◽  
...  
Keyword(s):  
Therapeutic Option ◽  
Case Series ◽  
Glottic Carcinoma ◽  
Transoral Laser Microsurgery ◽  
Laser Microsurgery ◽  
Average Hospital ◽  
Kaplan Meier ◽  
Prospective Case Series ◽  
Preservation Rate

OBJECTIVES: To report the oncology and functional outcomes of transoral laser microsurgery (TLM) for untreated glottic carcinoma. STUDY DESIGN: A 2 center prospective case series analysis. SETTING: Academic, tertiary referral centers. RESULTS: Seventy-six patients underwent TLM. Pathologic T stages were: T1, 45 (59%); T2, 21 (28%); T3, 5 (7%); and T4, 5 (7%). Five (7%) patients had neck dissections. Five (7%) patients received adjuvant radiotherapy. Mean follow-up was 42 months. Respective T1 and T2 5-year Kaplan-Meier estimates were: local control, 90% and 93%; loco-regional control, 90% and 93%; disease specific survival, 90% and 93%; and overall survival, 94% and 93%. The average hospital stay was 2 days. Two (3%) patients experienced major complications. The overall laryngeal preservation rate was 95% (72 of 76). CONCLUSIONS: TLM is a safe and effective treatment in select carcinoma of the glottic larynx. Low morbidity and mortality and short periods of hospitalization make TLM an attractive therapeutic option. SIGNIFICANCE: TLM is an emerging strategy in the treatment of laryngeal cancer.

Outcomes following Pediatric Auditory Brainstem Implant Surgery

2016 ◽  
Vol 155 (1) ◽  
pp. 133-138 ◽  
Author(s):  
Sidharth V. Puram ◽  
Samuel R. Barber ◽  
Elliott D. Kozin ◽  
Parth Shah ◽  
Aaron Remenschneider ◽  
...  
Keyword(s):  
Pediatric Patients ◽  
Case Series ◽  
Cerebrospinal Fluid Leak ◽  
The United States ◽  
Auditory Brainstem ◽  
Congenital Deafness ◽  
Device Failure ◽  
Auditory Brainstem Implant ◽  
Prospective Case Series ◽  
Fluid Leak

There are no approved Food and Drug Administration indications for pediatric auditory brainstem implant (ABI) surgery in the United States. Our prospective case series aims to determine the safety and feasibility of ABI surgery in pediatric patients <5 years old with congenital deafness at a tertiary North American center. The inclusion criterion was pre- or postlinguistic deafness in children not eligible for cochlear implantation. Seventeen candidates were evaluated (mean ± SD: age, 2.52 ± 0.39 years). Four patients underwent ABI surgery (age, 19.2 ± 3.43 months), including 4 primary procedures and 1 revision for device failure. Spontaneous device failure occurred in another subject postoperatively. No major/minor complications occurred, including cerebrospinal fluid leak, facial nerve injury, hematoma, and nonauditory stimulation. All subjects detected sound with environmental awareness, and several demonstrated babbling and mimicry. Poor durability of older implants underscores need for updated technology.

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