scholarly journals Effectiveness Of Eutectic Mixture Of Local Anaesthetics Vs Lidocaine As A Topical Anaesthetic Agent In Dentistry

Author(s):  
Prasanna Guru .E ◽  
2002 ◽  
Vol 27 (5) ◽  
pp. 462-464 ◽  
Author(s):  
T. M. LAWRENCE ◽  
V. V. DESAI

This randomized, double-blinded study assessed the effectiveness of a topical anaesthetic, eutectic mixture of local anaesthetics (EMLA), in reducing pain associated with carpal tunnel release performed under local anaesthetic. Fifty-six patients undergoing carpal tunnel release under local anaesthetic were randomized into either EMLA ( n=29) or placebo ( n=27) groups. Visual analogue pain scores were obtained for needle insertion, injection of anaesthetic and surgery itself. Pain scores were significantly less for needle insertion ( P=0.001) and injection of anaesthetic ( P=0.0005). Scores related to surgery were also lower in the EMLA group, but this did not reach statistical significance.


2000 ◽  
Vol 17 (Supplement 19) ◽  
pp. 167
Author(s):  
C. Karanastasi ◽  
M. Papanikolaou ◽  
M. Bala ◽  
D. Rapti ◽  
A. Charalambous

Author(s):  
Ajit Kumar Singh ◽  
Maruti Gupta ◽  
Padmini H. S.

Background: The aim of this study was to detect if intrathecal hyperbaric Levobupivacaine provided anaesthesia with more stable hemodynamic profile than 0.5% Hyperbaric Bupivacaine for lower limb and abdominal surgery.Methods: This observational study was carried out on 60 Adult patients between 18-65 Years of age, in ASA I and II undergoing lower abdominal surgery. Subarachnoid block using 3.0 ml of 0.5% hyperbaric Levobupivacaine (15 mg) was used as anaesthesia for surgery. Vitals recorded first in operation theatre were taken as baseline and were compared with subsequent readings till closure to judge the fall in blood pressure. Frequencies of parameters falling more than 30% from baseline, amount of IV fluids, vasopressors administered and complications were recorded. The data collected was displayed as mean with a standard deviation and frequency with percentage. Statistical analysis was performed using in stat computer software.Results: On analysis of the data it was found that fall in hemodynamic parameters was significantly lower in the Levobupivacaine group. It was observed that maximum onset of motor block was after 5 minutes, VAS after 4 minutes and loss of pinprick sensation was achieved at T-4 level after 4 minutes. Haemodynamic complications, which required therapeutic interventions, were hypotension (5%), bradycardia (3%), a total of 8%, who required urgent intervention as vasopressors and inotropes.Conclusions: 0.5% Hyperbaric Levobupivacaine, has onset of action similar to other local anaesthetics used for subarachnoid block, but has better hemodynamic profile in comparison to Hyperbaric 0.5% Bupivacaine, the commonly used local anaesthetic agent used for Spinal Anaesthesia.


UK-Vet Equine ◽  
2019 ◽  
Vol 3 (5) ◽  
pp. 169-174
Author(s):  
Jim Schumacher ◽  
Michael Schramme ◽  
John Schumacher

The notion that the accuracy of a nerve block correlates well with cutaneous sensation in the nerve's dermatome is false. A positive response to direct anaesthesia of a joint does not prove that the source of pain is within that joint or, conversely, that a negative response eliminates the joint as a source of pain. Local anaesthetics do appear to have the potential to cause long-term deleterious effects to joints when administered intra-articularly, in addition to the transient inflammatory response some are known to elicit. Administering epinephrine perineurally in combination with a local anaesthetic agent has been thought to have the potential to result in skin necrosis, subcutaneous swelling, and growth of white hair at the site of injection, but experience indicates that these complications are unlikely when epinephrine is administered at a concentration of 1:200 000 or less. The extent to which a local anaesthetic can migrate proximally following perineural injection can be underestimated.


2006 ◽  
Vol 126 (2) ◽  
pp. 223-224 ◽  
Author(s):  
T Mackle ◽  
D McShane

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