scholarly journals Third-Degree Atrioventricular Block in Clinically “Silent” Acute Myocardial Infarction

Medicinus ◽  
2018 ◽  
Vol 5 (3) ◽  
Author(s):  
Vito Damay

<p><em>Third-degree atrioventricular (AV) block also termed complete heart block is present when there is complete absence of conduction between atria and ventricles. In adults the most common causes are acute myocardial infarction and age-related degeneration of conduction system. Incidence of conduction block is reported to be 25-30 % in the setting of acute myocardial infarction (AMI) and is 2 to 3 times as commonly associated with inferior than anterior infarction. Proper diagnosis involves noninvasive diagnostic tests (12 lead electrocardiogram (ECG), Holter ECG, or stress/exercise ECG).</em></p><p><strong><em>Keywords: third-degree AV block, complete av block, acute myocardial infarction</em></strong></p>

2000 ◽  
Vol 30 (10) ◽  
pp. 1245 ◽  
Author(s):  
Boyoung Chung ◽  
Jong Won Ha ◽  
Donghoon Choi ◽  
Yangsoo Jang ◽  
Shin Ki Ahn ◽  
...  

2017 ◽  
Vol 63 (1) ◽  
pp. 394-402 ◽  
Author(s):  
Johannes Tobias Neumann ◽  
Nils Arne Sörensen ◽  
Francisco Ojeda ◽  
Tjark Schwemer ◽  
Jonas Lehmacher ◽  
...  

Abstract AIMS Serial measurements of high-sensitivity troponin are used to rule out acute myocardial infarction (AMI) with an assay specific cutoff at the 99th percentile. Here, we evaluated the performance of a single admission troponin with a lower cutoff combined with a low risk electrocardiogram (ECG) to rule out AMI. METHODS Troponin I measured with a high-sensitivity assay (hs-TnI) was determined at admission in 1040 patients presenting with suspected AMI (BACC study). To rule out AMI we calculated the negative predictive value (NPV) utilizing the optimal hs-TnI cutoff combined with a low risk ECG. The results were validated in 3566 patients with suspected AMI [2-h Accelerated Diagnostic Protocol to Assess Patients With Chest Pain Symptoms Using Contemporary Troponins as the Only Biomarker (ADAPT) studies]. Patients were followed for 6 or 12 months. RESULTS 184 of all patients were diagnosed with AMI. An hs-TnI cutoff of 3 ng/L resulted in a NPV of 99.3% (CI 97.3–100.0), ruling out 35% of all non-AMI patients. Adding the information of a low risk ECG resulted in a 100% (CI 97.5–100.0) NPV (28% ruled out). The 2 validation cohorts replicated the high NPV of this approach. The follow-up mortality in the ruled out population was low (0 deaths in BACC and Stenocardia, 1 death in ADAPT). CONCLUSIONS A single hs-TnI measurement on admission combined with a low risk ECG appears to rule out AMI safely without need for serial troponin testing. Trial Registration: www.clinicaltrials.gov (NCT02355457).


2005 ◽  
Vol 46 (6) ◽  
pp. 939-948 ◽  
Author(s):  
Yoshihisa Hirakawa ◽  
Yuichiro Masuda ◽  
Kazumasa Uemura ◽  
Masafumi Kuzuya ◽  
Takaya Kimata ◽  
...  

2009 ◽  
Vol 198 (1-6) ◽  
pp. 463-469 ◽  
Author(s):  
Hans Ibsen ◽  
Erik Kjøller ◽  
Janus Styperek ◽  
Asger Pedersen

Sign in / Sign up

Export Citation Format

Share Document