scholarly journals Association between two TIM-1 Promoter SNPs (-416G>C and -1454G>A) and Allergic Rhinitis in Egyptian Patients

Author(s):  
Amal Abdalmonem Ibrahim Amin ◽  
Marian Asaad Gerges
QJM ◽  
2021 ◽  
Vol 114 (Supplement_1) ◽  
Author(s):  
Maged M Refaat ◽  
Nermine A.E Melek ◽  
Eman E Ahmed ◽  
Osama M Abdellatif ◽  
Manar F Mohamed ◽  
...  

Abstract Background Allergy symptoms occur when the immune system overreacts to environmental allergens, such as pollen or dust, which are typically harmless to most individuals but induce a potentially severe reaction to those who are sensitive to them. Pollen is one of the main reasons to cause seasonal allergic respiratory diseases and it is influenced by multiple risk factors. Objective To determine the most prevalent types of allergenic pollens by skin prick testing among Egyptian patients with respiratory allergy (asthma and/or allergic rhinitis). Methods 200 adult patients, all were subjected to the following: full detailed medical history, clinical examination, asthma severity grading according to the GINA Guidelines, allergic rhinitis severity grading according to ARIA Guidelines, pulmonary Function tests for asthmatic patients. (PFTs), CBC with differential for detection of eosinophilic count, Skin prick testing (SPT) to common environmental allergens and common food allergen. Results The present study proved that the grass pollens; timothy grass and maize were the most prevalent pollens among Egyptian respiratory allergy patients. Conclusion Difference in results of SPT performed to patients across different countries is explained by the difference in climates, which affects pollination, Egypt is considered to have a dry, desert-like climate in addition to its coastal regions. Our results revealed that both timothy grass and maize pollens were the most prevalent among Egyptian respiratory allergy patients.


2020 ◽  
Vol 37 (2) ◽  
pp. 432-438
Author(s):  
Kassem Kassem ◽  
Mohsen Abdelrazik ◽  
Hamada Hashem ◽  
Heba Abdelkarim ◽  
Mona Mahmoud

Author(s):  
Kate W. Sjoerdsma ◽  
W. James Metzger

Eosinophils are important to the pathogenesis of allergic asthma, and are increased in bronchoalveolar lavage within four hours after bronchoprovocation of allergic asthmatic patients, and remain significantly increased up to 24 hours later. While the components of human eosinophil granules have been recently isolated and purified, the mechanisms of degranulation have yet to be elucidated.We obtained blood from two volunteers who had a history of allergic rhinitis and asthma and a positive skin test (5x5mm wheal) to Alternaria and Ragweed. Eosinophils were obtained using a modification of the method described by Roberts and Gallin.


1984 ◽  
Vol 15 (1) ◽  
pp. 44-50 ◽  
Author(s):  
Michael P. Rastatter ◽  
Melvin Hyman

A group of sophisticated listeners judged the nasal resonance characteristics of normal children versus children evidencing selected rhinologic disorders under three speaking conditions. Results showed that perceptions of denasality are influenced by both speakers and speaking tasks. That is, children with allergic rhinitis and edemic adenoids were perceived as being denasal when they produced VCV utterances and recited sentences. However, their resonance characteristics were deemed normal for vowel productions. Interestingly, children with severely deviated septums were judged to have normal nasal resonance under all speaking conditions. Clinical implications are discussed.


2007 ◽  
Vol 38 (2) ◽  
pp. 22
Author(s):  
SHARON WORCESTER
Keyword(s):  

Author(s):  
Niels Mygind ◽  
Lars Nielsen ◽  
Hans-Jürgen Hoffmann ◽  
Ronald Dahl ◽  
Henrik Jacobi

Author(s):  
Girish Vitalpur ◽  
Cleveland Moore ◽  
Raghubir Mangat ◽  
Raja Mouallem ◽  
Mosanda Mvula ◽  
...  

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