scholarly journals Teicoplanin-Induced Anaphylactic Reaction in Children: a Case Report

Author(s):  
Godwin Oligbu ◽  
Leila Ahmed

Teicoplanin is now increasingly used as a first-line prophylactic therapy for major surgical procedures, treatment of methicillin-resistant Staphylococcus aureus infections, and for those with reported penicillin allergy. Teicoplanin is rarely associated with anaphylaxis and there is limited information on the prevalence of teicoplanin- induced perioperative anaphylaxis. Here, we describe a case of a 12-year-old child with teicoplanin anaphylaxis peri-operatively.

Pharmacy ◽  
2018 ◽  
Vol 6 (4) ◽  
pp. 110 ◽  
Author(s):  
Godwin Oligbu ◽  
Leila Ahmed

Teicoplanin is now increasingly used as a first-line prophylactic therapy for major surgical procedures, treatment of methicillin-resistant Staphylococcus aureus infections and for those with reported penicillin allergy. Teicoplanin is rarely associated with anaphylaxis and there is limited information on the prevalence of teicoplanin-induced perioperative anaphylaxis. Here, we describe a case of a 12-year-old child with teicoplanin-induced anaphylaxis peri-operatively.


2020 ◽  
Vol 34 ◽  
pp. 205873842092571
Author(s):  
Chanmei Lv ◽  
Jiantao Lv ◽  
Yue Liu ◽  
Qifeng Liu ◽  
Dongna Zou

The infection of the bone marrow system caused by methicillin-resistant Staphylococcus aureus (MRSA) leads to a variety of common diseases which usually occur in children under the age of 12. Vancomycin (VCM) is the first-line therapy for MRSA-caused serious infections such as bacteremia, infective endocarditis, osteomyelitis, meningitis, pneumonia, and severe skin and soft-tissue infection (e.g. necrotizing fasciitis) with a recommended dosage of 15–20 μg/mL. In this study, we first report a case of a child with MRSA-caused osteomyelitis who was successfully cured by VCM at a concentration of 4.86 μg/mL. VCM’s clinical daily dose of more than 4 g was of concern in light of recent evidence suggesting the increased risks of nephrotoxicity and red man syndrome when Cmin ⩾15 μg/mL and doses ⩾10 mg/kg in children. As far as we know, this is the first report on the lower dose of VCM in children with MRSA osteomyelitis.


Medicina ◽  
2010 ◽  
Vol 46 (1) ◽  
pp. 31
Author(s):  
Rūta Kupstaitė ◽  
Asta Baranauskaitė ◽  
Margarita Pileckytė ◽  
Audrius Sveikata ◽  
Edmundas Kaduševičius ◽  
...  

Vancomycin is widely used against methicillin-resistant Staphylococcus aureus infections, but it is associated with many adverse effects such as nephrotoxicity, ototoxicity, gastrointestinal disturbances, blood disorders, and two types of hypersensitivity reactions – an anaphylactoid reaction known as “red man syndrome” and anaphylaxis. We report a case of a 23-year-old man who developed a vancomycin-induced anaphylactic reaction in the treatment of methicillin-resistant Staphylococcus aureus infection.


2020 ◽  
Vol 26 (10) ◽  
pp. 1078-1081
Author(s):  
Kentaro Shimizu ◽  
Ayumi Takahashi ◽  
Daisuke Motooka ◽  
Shota Nakamura ◽  
Kazunori Tomono ◽  
...  

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