Chronic viral hepatitis and inflammatory bowel disease

2021 ◽  
Vol 11 (2) ◽  
pp. 29-34
Author(s):  
G.V. Volynets ◽  
◽  
A.I. Khavkin ◽  
Keyword(s):  
Inflammatory Bowel Disease ◽  
Chronic Hepatitis ◽  
Hepatitis C ◽  
Hepatitis B ◽  
Viral Hepatitis ◽  
Immunosuppressive Therapy ◽  
Chronic Hepatitis C ◽  
Bowel Disease ◽  
Chronic Viral Hepatitis ◽  
Inflammatory Bowel

The article presents the results of a literature review devoted to the study of the problems of the combined course of inflammatory bowel diseases (IBD), which include ulcerative colitis (UC) and Crohn's disease (CD), and chronic viral hepatitis (CVH) – chronic hepatitis B (CHB) and chronic hepatitis C (CHC). The frequency of occurrence of CHB and CHC in IBD in different countries is presented, which ranges from 1 to 9%. The clinical course of these combined diseases, the possibility of reactivation of hepatitis B virus (HBV) and hepatitis C virus (HCV) during immunosuppressive therapy are described. Recommendations on the specifics of examination and management of patients with combined pathology of IBD and CVH are presented. Conclusion. The combined pathology of IBD and CVH is a significant public health problem around the world that requires further large-scale study. The use of immunosuppressive therapy for IBD can be accompanied by the activation of HBV and HCV infection, therefore, the management of such patients should be individualized. Key words: inflammatory bowel disease, chronic hepatitis B, chronic hepatitis C, immunosuppressive therapy

scholarly journals CHRONIC VIRAL HEPATITIS AND INFLAMMATORY BOWEL DISEASE

2021 ◽  
Vol 5 (2) ◽  
pp. 111-117
Author(s):  
G. V. Volynets ◽  
Keyword(s):  
Chronic Hepatitis ◽  
Hepatitis C ◽  
Hepatitis B ◽  
Viral Hepatitis ◽  
Immunosuppressive Therapy ◽  
Public Health Problem ◽  
Chronic Viral Hepatitis ◽  
Bowel Diseases ◽  
Significant Public Health ◽  
Inflammatory Bowel

The article presents the results of a literature review devoted to the study of the problems of the concurrent course of inflammatory bowel diseases (IBD), which include ulcerative colitis (UC) and Crohn's disease (CD), as well as chronic viral hepatitis (CVH) - chronic hepatitis B (CHB) and chronic hepatitis C (CHC). The prevalence of CHB and CHC in IBD in different countries ranges from 1% to 9%. The clinical course of these concurrent diseases, the possibility of hepatitis B virus (HBV) and hepatitis C virus (HCV) reactivation during immunosuppressive therapy are described. Recommendations on the peculiarities of examination and management of patients with concurrent pathology of IBD and CVH are presented. The combined pathology of IBD and CVH is a significant public health problem worldwide that requires further largescale study. The use of immunosuppressive therapy for IBD can be accompanied by the activation of HBV and HCV infection, therefore, the management of such patients should occur on an individual basis.

scholarly journals Chronic hepatitis C, inflammatory bowel disease and interferon therapy

2012 ◽  
Vol 6 (5) ◽  
pp. 626-627 ◽  
Author(s):  
Cumali Efe ◽  
Emir Charles Roach ◽  
Tugrul Purnak ◽  
Ersan Ozaslan
Keyword(s):  
Inflammatory Bowel Disease ◽  
Chronic Hepatitis ◽  
Hepatitis C ◽  
Chronic Hepatitis C ◽  
Bowel Disease ◽  
Interferon Therapy ◽  
Inflammatory Bowel

Association between Hepatic Steatosis and Fibrosis in Chronic Viral Hepatitis B and C Patients

2021 ◽  
Vol 104 (3) ◽  
pp. 396-401
Keyword(s):  
Chronic Hepatitis ◽  
Hepatitis C ◽  
Hepatitis B ◽  
Liver Biopsy ◽  
Viral Hepatitis ◽  
Hepatic Steatosis ◽  
Chronic Hepatitis C ◽  
Chronic Viral Hepatitis ◽  
Fibrosis Stage ◽  
Viral Hepatitis B

Background: Chronic viral hepatitis B (CHB) and chronic viral hepatitis C (CHC) are important causes of chronic liver disease and cancer development in patients with progressive fibrosis, which are often associated with hepatic steatosis. Objective: To evaluate the prevalence of hepatic steatosis in Thai CHB and CHC patients and its correlation with fibrosis stage. Materials and Methods: The authors examined the liver biopsy findings of CHB and CHC patients diagnosed at Srinagarind Hospital between 2016 and 2018. Routine Hematoxylin and Eosin staining with PAS, and Masson trichrome staining were used to evaluate fibrosis and steatosis histology according to the METAVIR and SAF scoring systems. The association were evaluated by chi-square, Fisher’s exact, and Spearman’s correlation tests with statistical significance defined as p-value less than 0.05. Results: One hundred thirty-eight cases were examined. The mean age of the patients was 45 years. Chronic hepatitis C was detected in 96 patients (69.6%), and CHB was detected in 42 patients (30.4%). Liver biopsies showed steatosis in 73 patients (52.9%; grade 1: 67.1%, grade 2: 19.2%, and grade 3: 13.7%). Steatosis was associated with viral hepatitis profile (OR 2.534, 95% CI 1.087 to 5.904, p=0.031); however, the METAVIR fibrosis stage associated with the age of the patient (OR 1.059, 95% CI 1.012 to 1.109, p=0.014) and METAVIR activity (OR 4.924, 95% CI 2.443 to 9.967, p<0.0001). Conclusion: Hepatic steatosis is commonly present in Thai CHC and CHB patients, and especially in the former. Steatosis was associated with viral hepatitis profile. Hepatic fibrosis is associated only with the age of the patient and METAVIR activity. Keywords: Chronic hepatitis B, Chronic hepatitis C, Steatosis, Fibrosis, METAVIR, SAF score, Liver biopsy

scholarly journals Gastroenterology Cases of Cutaneous Leukocytoclastic Vasculitis

2013 ◽  
Vol 2013 ◽  
pp. 1-4
Author(s):  
Cumali Karatoprak ◽  
Elif Arabaci ◽  
Kemal Yildiz ◽  
Mustafa Cakirca ◽  
Mehmet Ali Cikrikcioglu ◽  
...  
Keyword(s):  
Inflammatory Bowel Disease ◽  
Chronic Hepatitis ◽  
Crohn’S Disease ◽  
Hepatitis C ◽  
Chronic Hepatitis C ◽  
Ischemic Colitis ◽  
Bowel Disease ◽  
Leukocytoclastic Vasculitis ◽  
Underlying Disease ◽  
Inflammatory Bowel

Rarely, leukocytoclastic vasculitis can result from ischemic colitis, inflammatory bowel disease, and cryoglobulinemia. There is no established standard for the treatment of leukocytoclastic vasculitis associated with gastroenterologic diseases. This paper presents three cases of leukoytoclastic vasculitis, each of which is associated with a different gastroenterologic condition: ischemic colitis, Crohn’s disease, and chronic hepatitis C. Each condition went into remission by treatment of leukocytoclastic vasculitis, regardless of the underlying disease.

AF.91 TRENDS OF LIVER STIFFNESS IN INFLAMMATORY BOWEL DISEASE WITH CHRONIC HEPATITIS C

2021 ◽  
Vol 53 ◽  
pp. S179
Author(s):  
G. Losurdo ◽  
A. Iannone ◽  
A. Contaldo ◽  
M. Barone ◽  
E. Ierardi ◽  
...  
Keyword(s):  
Inflammatory Bowel Disease ◽  
Chronic Hepatitis ◽  
Hepatitis C ◽  
Chronic Hepatitis C ◽  
Bowel Disease ◽  
Liver Stiffness ◽  
Inflammatory Bowel

Liver dysfunction related to hepatitis B and C in patients with inflammatory bowel disease treated with immunosuppressive therapy

Gut ◽  
2010 ◽  
Vol 59 (10) ◽  
pp. 1340-1346 ◽  
Author(s):  
C. Loras ◽  
J. P. Gisbert ◽  
M. Minguez ◽  
O. Merino ◽  
L. Bujanda ◽  
...  
Keyword(s):  
Inflammatory Bowel Disease ◽  
Hepatitis B ◽  
Immunosuppressive Therapy ◽  
Liver Dysfunction ◽  
Bowel Disease ◽  
Inflammatory Bowel
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