Treatment rationale and design of the PROLONG study: safety and efficacy of pembrolizumab as first-line therapy for elderly patients with non-small cell lung cancer

Takeshi Masuda; Kazunori Fujitaka; Nobuhisa Ishikawa; Kikuo Nakano; Masahiro Yamasaki; Souichi Kitaguchi; Ken Masuda; Kakuhiro Yamaguchi; Shinjiro Sakamoto; Yasushi Horimasu; Shigeo Kawase; Shintaro Miyamoto; Taku Nakashima; Hiroshi Iwamoto; Naoki Shiota; Tadashi Senoo; Yoshikazu Awaya; Tomohiro Kondo; Takashi Yoshida; Hironobu Hamada; Isao Murakami; Noboru Hattori

doi:10.21037/jtd.2019.12.46

Treatment rationale and design of the PROLONG study: safety and efficacy of pembrolizumab as first-line therapy for elderly patients with non-small cell lung cancer

Journal of Thoracic Disease ◽

10.21037/jtd.2019.12.46 ◽

2020 ◽

Vol 12 (3) ◽

pp. 1079-1084

Author(s):

Takeshi Masuda ◽

Kazunori Fujitaka ◽

Nobuhisa Ishikawa ◽

Kikuo Nakano ◽

Masahiro Yamasaki ◽

...

Keyword(s):

Lung Cancer ◽

Elderly Patients ◽

Small Cell Lung Cancer ◽

Cell Lung Cancer ◽

Small Cell ◽

Small Cell Lung ◽

First Line ◽

Safety And Efficacy ◽

First Line Therapy ◽

Line Therapy

Download Full-text

Faculty Opinions recommendation of Safety and efficacy of weekly nab®-paclitaxel in combination with carboplatin as first-line therapy in elderly patients with advanced non-small-cell lung cancer.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.717964584.793468557 ◽

2013 ◽

Author(s):

Bruno Andreoni ◽

Gianmarco Contino

Keyword(s):

Lung Cancer ◽

Elderly Patients ◽

Small Cell Lung Cancer ◽

Cell Lung Cancer ◽

Small Cell ◽

Small Cell Lung ◽

First Line ◽

Safety And Efficacy ◽

First Line Therapy ◽

Line Therapy

Download Full-text

Faculty Opinions recommendation of Safety and efficacy of weekly nab®-paclitaxel in combination with carboplatin as first-line therapy in elderly patients with advanced non-small-cell lung cancer.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.717964584.793468275 ◽

2012 ◽

Author(s):

Christopher Steer

Keyword(s):

Lung Cancer ◽

Elderly Patients ◽

Small Cell Lung Cancer ◽

Cell Lung Cancer ◽

Small Cell ◽

Small Cell Lung ◽

First Line ◽

Safety And Efficacy ◽

First Line Therapy ◽

Line Therapy

Download Full-text

Faculty of 1000 evaluation for Safety and efficacy of weekly nab®-paclitaxel in combination with carboplatin as first-line therapy in elderly patients with advanced non-small-cell lung cancer.

F1000 - Post-publication peer review of the biomedical literature ◽

10.3410/f.717964584.793474497 ◽

2013 ◽

Author(s):

Siri Rostoft

Keyword(s):

Lung Cancer ◽

Elderly Patients ◽

Small Cell Lung Cancer ◽

Cell Lung Cancer ◽

Small Cell ◽

Small Cell Lung ◽

First Line ◽

Safety And Efficacy ◽

First Line Therapy ◽

Line Therapy

Download Full-text

Safety and efficacy of weekly nab®-paclitaxel in combination with carboplatin as first-line therapy in elderly patients with advanced non-small-cell lung cancer

Annals of Oncology ◽

10.1093/annonc/mds461 ◽

2013 ◽

Vol 24 (2) ◽

pp. 314-321 ◽

Cited By ~ 71

Author(s):

M.A. Socinski ◽

C.J. Langer ◽

I. Okamoto ◽

J.K. Hon ◽

V. Hirsh ◽

...

Keyword(s):

Lung Cancer ◽

Elderly Patients ◽

Small Cell Lung Cancer ◽

Cell Lung Cancer ◽

Small Cell ◽

Small Cell Lung ◽

First Line ◽

Safety And Efficacy ◽

First Line Therapy ◽

Line Therapy

Download Full-text

Weekly docetaxel as first-line therapy for elderly patients with advanced non-small cell lung cancer (NSCLC)

Lung Cancer ◽

10.1016/s0169-5002(00)80203-2 ◽

2000 ◽

Vol 29 (1) ◽

pp. 63 ◽

Cited By ~ 1

Author(s):

J.D Hainsworth ◽

H.A Burris ◽

L.H Morrissey ◽

S Litchy ◽

F.A Greco

Keyword(s):

Lung Cancer ◽

Elderly Patients ◽

Small Cell Lung Cancer ◽

Cell Lung Cancer ◽

Small Cell ◽

Small Cell Lung ◽

First Line ◽

Weekly Docetaxel ◽

First Line Therapy ◽

Line Therapy

Download Full-text

Weekly nab-Paclitaxel in Combination With Carboplatin as First-Line Therapy in Patients With Advanced Non–Small-Cell Lung Cancer: Analysis of Safety and Efficacy in Patients With Renal Impairment

Clinical Lung Cancer ◽

10.1016/j.cllc.2014.09.003 ◽

2015 ◽

Vol 16 (2) ◽

pp. 112-120 ◽

Cited By ~ 12

Author(s):

Corey J. Langer ◽

Vera Hirsh ◽

Amy Ko ◽

Markus F. Renschler ◽

Mark A. Socinski

Keyword(s):

Lung Cancer ◽

Renal Impairment ◽

Small Cell Lung Cancer ◽

Cell Lung Cancer ◽

Small Cell ◽

Small Cell Lung ◽

First Line ◽

Safety And Efficacy ◽

First Line Therapy ◽

Line Therapy

Download Full-text

Safety and efficacy analysis by histology of weekly nab-paclitaxel in combination with carboplatin as first-line therapy in patients with advanced non-small-cell lung cancer

Annals of Oncology ◽

10.1093/annonc/mdt235 ◽

2013 ◽

Vol 24 (9) ◽

pp. 2390-2396 ◽

Cited By ~ 40

Author(s):

M.A. Socinski ◽

I. Okamoto ◽

J.K. Hon ◽

V. Hirsh ◽

S.R. Dakhil ◽

...

Keyword(s):

Lung Cancer ◽

Small Cell Lung Cancer ◽

Cell Lung Cancer ◽

Small Cell ◽

Small Cell Lung ◽

First Line ◽

Safety And Efficacy ◽

Efficacy Analysis ◽

First Line Therapy ◽

Line Therapy

Download Full-text

O15‐4: The efficacy of gefitinib as a first‐line therapy in elderly patients with advanced non‐small cell lung cancer with EGFR mutations

Respirology ◽

10.1111/resp.14149_89 ◽

2021 ◽

Vol 26 (S3) ◽

pp. 41-42

Keyword(s):

Lung Cancer ◽

Elderly Patients ◽

Small Cell Lung Cancer ◽

Cell Lung Cancer ◽

Small Cell ◽

Egfr Mutations ◽

Small Cell Lung ◽

First Line ◽

First Line Therapy ◽

Line Therapy

Download Full-text

Weekly nab-Paclitaxel in Combination With Carboplatin as First-Line Therapy in Patients With Advanced Non–Small-Cell Lung Cancer: Analysis of Safety and Efficacy in Patients With Diabetes

Clinical Lung Cancer ◽

10.1016/j.cllc.2016.04.002 ◽

2016 ◽

Vol 17 (5) ◽

pp. 367-374 ◽

Cited By ~ 3

Author(s):

Vera Hirsh ◽

Amy Ko ◽

Richard Pilot ◽

Markus F. Renschler ◽

Mark A. Socinski

Keyword(s):

Lung Cancer ◽

Small Cell Lung Cancer ◽

Cell Lung Cancer ◽

Small Cell ◽

Small Cell Lung ◽

First Line ◽

Safety And Efficacy ◽

First Line Therapy ◽

Line Therapy ◽

Patients With Diabetes

Download Full-text

Cytotoxic Chemotherapy as First-Line Therapy for Advanced Non-Small-Cell Lung Cancer in Taiwan: Daily Practice

Journal of Cancer ◽

10.7150/jca.15180 ◽

2016 ◽

Vol 7 (11) ◽

pp. 1515-1523 ◽

Cited By ~ 3

Author(s):

Yi-Hsin Liang ◽

Yu-Yun Shao ◽

Bin-Chi Liao ◽

Ho-Sheng Lee ◽

James Chih-Hsin Yang ◽

...

Keyword(s):

Lung Cancer ◽

Small Cell Lung Cancer ◽

Cell Lung Cancer ◽

Daily Practice ◽

Cytotoxic Chemotherapy ◽

Small Cell ◽

Small Cell Lung ◽

First Line ◽

First Line Therapy ◽

Line Therapy

Download Full-text