Appropriate treatment strategy for ground glass opacity—dominant non-small cell lung cancer

2018 ◽  
Vol 3 ◽  
pp. 34-34 ◽  
Author(s):  
Yoshinori Handa ◽  
Yasuhiro Tsutani ◽  
Morihito Okada
Keyword(s):  
Lung Cancer ◽  
Small Cell Lung Cancer ◽  
Cell Lung Cancer ◽  
Treatment Strategy ◽  
Ground Glass Opacity ◽  
Small Cell ◽  
Ground Glass ◽  
Small Cell Lung ◽  
Appropriate Treatment

scholarly journals Is segmentectomy indicative for small-sized non-small cell lung cancer in the basal segments with a small ground-glass opacity component?

2017 ◽  
Vol 9 (10) ◽  
pp. 3501-3505 ◽  
Author(s):  
Terumoto Koike ◽  
Akihiro Nakamura ◽  
Yuki Shimizu ◽  
Tatsuya Goto ◽  
Akihiko Kitahara ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Small Cell Lung Cancer ◽  
Cell Lung Cancer ◽  
Ground Glass Opacity ◽  
Small Cell ◽  
Ground Glass ◽  
Small Cell Lung

scholarly journals Clinical features and prognosis of clinical N0 non-small cell lung cancer exceeding 30 mm

2020 ◽  
Vol 50 (11) ◽  
pp. 1306-1312
Author(s):  
Atsushi Kagimoto ◽  
Yasuhiro Tsutani ◽  
Yoshinori Handa ◽  
Takahiro Mimae ◽  
Yoshihiro Miyata ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Small Cell Lung Cancer ◽  
Cell Lung Cancer ◽  
Solid Tumour ◽  
Ground Glass Opacity ◽  
Small Cell ◽  
Ground Glass ◽  
Recurrence Free Survival ◽  
Small Cell Lung ◽  
Free Survival

Abstract Objectives This study aimed to determine the characteristics, ground glass opacity ratio and prognosis of patients with clinical N0 non-small cell lung cancer tumours exceeding 30 mm in size. Methods Patients with clinical N0 non-small cell lung cancer and total tumour size >30 mm on preoperative computed tomography who underwent complete resection with lobectomy between January 2007 and December 2017 were included. The patients were divided into three groups: pure solid tumour, low ground glass opacity ratio (1–39%) tumour and high ground glass opacity ratio (≥40%) tumour. The cut-off line was determined based on the recurrence rate for every 10% ground glass opacity ratio. Results Among the 227 study patients, 129 (56.8%) had a pure solid tumour, 54 (23.8%) had a low ground glass opacity ratio tumour and 44 (19.4%) had a high ground glass opacity ratio tumour. Three-year recurrence-free survival was significantly shorter in patients with a pure solid tumour (57.4%) than in patients with a low ground glass opacity ratio (74.5%; P = 0.009) or a high ground glass opacity ratio tumour (92.1%; P < 0.001). Multivariable analysis showed that ground glass opacity ratio was a significant independent prognostic factor for recurrence-free survival (hazard ratio, 0.175; P = 0.037). Conclusion Pure solid tumours comprised a large proportion of non-small cell lung cancer tumours >30 mm in size and their prognosis was poor. The presence of ground glass opacity and their relative proportion affect prognosis in patients with clinical N0 non-small cell lung cancer tumours >30 mm in size, similar to those with small-sized tumours.

scholarly journals Management of Ground-Glass Opacity Lesions Detected in Patients with Otherwise Operable Non-small Cell Lung Cancer

2009 ◽  
Vol 4 (10) ◽  
pp. 1242-1246 ◽  
Author(s):  
Hong Kwan Kim ◽  
Yong Soo Choi ◽  
Kwhanmien Kim ◽  
Young Mog Shim ◽  
Sun Young Jeong ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Small Cell Lung Cancer ◽  
Cell Lung Cancer ◽  
Ground Glass Opacity ◽  
Small Cell ◽  
Ground Glass ◽  
Small Cell Lung

Ground-glass opacity lesions on computed tomography during postoperative surveillance for primary non-small cell lung cancer

Lung Cancer ◽  
2012 ◽  
Vol 76 (1) ◽  
pp. 56-60 ◽  
Author(s):  
Akira Haro ◽  
Tokujiro Yano ◽  
Mikihiro Kohno ◽  
Tsukihisa Yoshida ◽  
Tatsuro Okamoto ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Lung Cancer ◽  
Small Cell Lung Cancer ◽  
Cell Lung Cancer ◽  
Ground Glass Opacity ◽  
Small Cell ◽  
Ground Glass ◽  
Small Cell Lung ◽  
Postoperative Surveillance

scholarly journals Transition of Treatment for Ground Glass Opacity–Dominant Non-Small Cell Lung Cancer

2021 ◽  
Vol 11 ◽  
Author(s):  
Yoshinori Handa ◽  
Yasuhiro Tsutani ◽  
Morihito Okada
Keyword(s):  
Lung Cancer ◽  
Small Cell Lung Cancer ◽  
Cell Lung Cancer ◽  
Ground Glass Opacity ◽  
Small Cell ◽  
Ground Glass ◽  
Maximum Diameter ◽  
Sublobar Resection ◽  
Small Cell Lung ◽  
Lung Cancers

Lobectomy has been the standard surgical treatment for non-small cell lung cancer (NSCLC). Over the decades, with the dramatic development of radiographic tools, such as high-resolution computed tomography (HRCT), and the widespread practice of low-dose helical CT for screening, the number of cases diagnosed with small-cell lung cancers with ground glass opacity (GGO) at early stages has been increasing. Accordingly, mainly after 2000, many retrospective studies and prospective trials have shown that patients with lung adenocarcinoma with GGO have a good prognosis and may be candidates for sublobar resection. Previous studies indicated that HRCT findings including the maximum diameter of the tumor, GGO ratio, and a consolidation/tumor ratio (CTR) are simple and useful tools to predict tumor invasiveness and prognosis in patients with NSCLC with GGO. Thus, sublobar resection may be considered a “standard therapy” for peripheral GGO-dominant small-cell lung adenocarcinomas. Ultimately, some of such tumors might not require surgical resection. A multicenter, prospective study has just begun in Japan to evaluate the validity of follow-up for small-sized GGO-dominant small-cell lung cancer. Lung cancers that do not require surgery should be identified. This study reviewed retrospective and prospective studies on GGO tumors and discussed the treatment strategies for such tumors.

Sign in / Sign up

Export Citation Format

Share Document