scholarly journals Effects of Moving Cupping Therapy for Plaque Psoriasis: A Protocol for a Randomised Multicentre Clinical Trial

2020 ◽  
Author(s):  
Meng Xing ◽  
Xiaoning Yan ◽  
Suqing Yang ◽  
Linge Li ◽  
Liping Gong ◽  
...  
Keyword(s):  
Plaque Psoriasis ◽  
Controlled Trial ◽  
Life Quality ◽  
Cupping Therapy ◽  
The Body ◽  
Public Hospitals ◽  
Moving Cupping Therapy ◽  
Comprehensive Therapy ◽  
Patient Reported ◽  
Basic Treatment

Abstract Background: The clinical treatment of plaque psoriasis is based on comprehensive therapy, which is expensive and unsatisfactory, and some of the drugs currently used have serious side effects. Moving cupping therapy has been used clinically for thousands of years in China and has the advantage of being inexpensive and easy to perform. It is now widely used in public hospitals in China for the treatment of psoriasis. However, at present, a comprehensive evaluation of the current clinical evidence regarding its use is lacking. This study aims to evaluate the efficacy and safety of moving cupping in the treatment of plaque psoriasis. Methods and analysis: A multicentre, two-arm parallel group, single-blind randomised controlled trial will be conducted in six academic and non-academic hospitals in China. A total of 110 adult patients (aged 18-65 years) who meet the inclusion criteria are now being recruited. Participants will receive (1) basic treatment combined with moving cupping therapy or (2) basic treatment combined with moving cupping placebo. The treatment cycle will be 4 weeks, and the treatment efficacy will be assessed weekly using the Psoriasis Area and Severity Index during the treatment period and the follow-up visits at weeks 6 and 8. The body surface area, physician's global assessment, Dermatology Life Quality Index, patient-reported quality of life, visual analogy scale, traditional Chinese medication syndrome scoring scale, combined medication, and adverse events will also be recorded and compared to the baseline values. Discussion: The results of this trial may help make better decisions in the treatment of plaque psoriasis. If the results are considered to be favorable, this ancient Chinese medicine therapy may be worthier of promotion because of its convenience and cheap advantages to benefit patients. Trial registration: This study has been registered at ClinicalTrials.gov under the identifier number NCT03952676. Registered on 15 May 2019.

scholarly journals Effects of Moving Cupping Therapy for Plaque Psoriasis: A Protocol for a Randomised Multicentre Clinical Trial

2019 ◽  
Author(s):  
Meng Xing ◽  
Xiaoning Yan ◽  
Suqing Yang ◽  
Linge Li ◽  
Liping Gong ◽  
...  
Keyword(s):  
Plaque Psoriasis ◽  
Controlled Trial ◽  
Life Quality ◽  
Cupping Therapy ◽  
The Body ◽  
Public Hospitals ◽  
Moving Cupping Therapy ◽  
Comprehensive Therapy ◽  
Patient Reported ◽  
Basic Treatment

Abstract ABSTRACT Background: The clinical treatment of plaque psoriasis is based on comprehensive therapy, which is expensive and unsatisfactory, and some of the drugs currently used have serious side effects. Moving cupping therapy has been used clinically for thousands of years in China and has the advantage of being inexpensive and easy to perform. It is now widely used in public hospitals in China for the treatment of psoriasis. However, at present, a comprehensive evaluation of the current clinical evidence regarding its use is lacking. This study aims to evaluate the efficacy and safety of moving cupping in the treatment of plaque psoriasis. Methods and analysis: A multicentre, two-arm parallel group, single-blind randomised controlled trial will be conducted in six academic and non-academic hospitals in China. A total of 110 adult patients (aged 18-65 years) who meet the inclusion criteria are now being recruited. Participants will receive (1) basic treatment combined with moving cupping therapy or (2) basic treatment combined with moving cupping placebo. The treatment cycle will be 4 weeks, and the treatment efficacy will be assessed weekly using the Psoriasis Area and Severity Index during the treatment period and the follow-up visits at weeks 6 and 8. The body surface area, physician's global assessment, Dermatology Life Quality Index, patient-reported quality of life, visual analogy scale, traditional Chinese medication syndrome scoring scale, combined medication, and adverse events will also be recorded and compared to the baseline values. Discussion: The results of this trial may help make better decisions in the treatment of plaque psoriasis. If the results are considered to be favorable, this ancient Chinese medicine therapy may be worthier of promotion because of its convenience and cheap advantages to benefit patients. Trial registration: This study has been registered at ClinicalTrials.gov under the identifier number NCT03952676. Registered on 15 May 2019.

scholarly journals Effects of Moving Cupping Therapy for Plaque Psoriasis: A Protocol for a Randomised Multicentre Clinical Trial

2020 ◽  
Author(s):  
Meng Xing ◽  
Xiaoning Yan ◽  
Suqing Yang ◽  
Linge Li ◽  
Liping Gong ◽  
...  
Keyword(s):  
Plaque Psoriasis ◽  
Controlled Trial ◽  
Life Quality ◽  
Cupping Therapy ◽  
The Body ◽  
Public Hospitals ◽  
Moving Cupping Therapy ◽  
Comprehensive Therapy ◽  
Patient Reported ◽  
Basic Treatment

Abstract Background: The clinical treatment of plaque psoriasis is based on comprehensive therapy, which is expensive and unsatisfactory, and some of the drugs currently used have serious side effects. Moving cupping therapy has been used clinically for thousands of years in China and has the advantage of being inexpensive and easy to perform. It is now widely used in public hospitals in China for the treatment of psoriasis. However, at present, a comprehensive evaluation of the current clinical evidence regarding its use is lacking. This study aims to evaluate the efficacy and safety of moving cupping in the treatment of plaque psoriasis. Methods and analysis: A multicentre, two-arm parallel group, single-blind randomised controlled trial will be conducted in six academic and non-academic hospitals in China. A total of 110 adult patients (aged 18-65 years) who meet the inclusion criteria are now being recruited. Participants will receive (1) basic treatment combined with moving cupping therapy or (2) basic treatment combined with moving cupping placebo. The treatment cycle will be 4 weeks, and the treatment efficacy will be assessed weekly using the Psoriasis Area and Severity Index during the treatment period and the follow-up visits at weeks 6 and 8. The body surface area, physician's global assessment, Dermatology Life Quality Index, patient-reported quality of life, visual analogy scale, traditional Chinese medication syndrome scoring scale, combined medication, and adverse events will also be recorded and compared to the baseline values. Discussion: The results of this trial may help make better decisions in the treatment of plaque psoriasis. If the results are considered to be favorable, this ancient Chinese medicine therapy may be worthier of promotion because of its convenience and cheap advantages to benefit patients. Trial registration: This study has been registered at ClinicalTrials.gov under the identifier number NCT03952676. Registered on 15 May 2019.

scholarly journals Effects of moving cupping therapy for plaque psoriasis: study protocol for a randomized multicenter clinical trial

Trials ◽  
2020 ◽  
Vol 21 (1) ◽  
Author(s):  
Meng Xing ◽  
Xiaoning Yan ◽  
Suqing Yang ◽  
Linge Li ◽  
Liping Gong ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Study Protocol ◽  
Plaque Psoriasis ◽  
Cupping Therapy ◽  
Multicenter Clinical Trial ◽  
Moving Cupping Therapy

scholarly journals Moving cupping therapy for plaque psoriasis

Medicine ◽  
2020 ◽  
Vol 99 (41) ◽  
pp. e22539
Author(s):  
Meng Xing ◽  
Xiaojie Ding ◽  
Jinjing Zhang ◽  
Le Kuai ◽  
Yi Ru ◽  
...  
Keyword(s):  
Plaque Psoriasis ◽  
Cupping Therapy ◽  
Moving Cupping Therapy

Impact of Preoperative Opioid Use on 2-Year Patient-Reported Outcomes in Knee Surgery Patients

2020 ◽  
Author(s):  
Ali Aneizi ◽  
Patrick M. J. Sajak ◽  
Aymen Alqazzaz ◽  
Tristan Weir ◽  
Cameran I. Burt ◽  
...  
Keyword(s):  
Physical Function ◽  
Patient Reported Outcomes ◽  
Knee Surgery ◽  
The Body ◽  
Pain Interference ◽  
Opioid Use ◽  
Opioid Prescription ◽  
Social Satisfaction ◽  
Patient Reported ◽  
Met Expectations

AbstractThe objectives of this study are to assess perioperative opioid use in patients undergoing knee surgery and to examine the relationship between preoperative opioid use and 2-year postoperative patient-reported outcomes (PROs). We hypothesized that preoperative opioid use and, more specifically, higher quantities of preoperative opioid use would be associated with worse PROs in knee surgery patients. We studied 192 patients undergoing knee surgery at a single urban institution. Patients completed multiple PRO measures preoperatively and 2-year postoperatively, including six patient-reported outcomes measurement information system (PROMIS) domains; the International Knee Documentation Committee (IKDC) questionnaire, numeric pain scale (NPS) scores for the operative knee and the rest of the body, Marx's knee activity rating scale, Tegner's activity scale, International Physical Activity Questionnaire, as well as measures of met expectations, overall improvement, and overall satisfaction. Total morphine equivalents (TMEs) were calculated from a regional prescription monitoring program. Eighty patients (41.7%) filled an opioid prescription preoperatively, and refill TMEs were significantly higher in this subpopulation. Opioid use was associated with unemployment, government insurance, smoking, depression, history of prior surgery, higher body mass index, greater comorbidities, and lower treatment expectations. Preoperative opioid use was associated with significantly worse 2-year scores on most PROs, including PROMIS physical function, pain interference, fatigue, social satisfaction, IKDC, NPS for the knee and rest of the body, and Marx's and Tegner's scales. There was a significant dose-dependent association between greater preoperative TMEs and worse scores for PROMIS physical function, pain interference, fatigue, social satisfaction, NPS body, and Marx's and Tegner's scales. Multivariable analysis confirmed that any preoperative opioid use, but not quantity of TMEs, was an independent predictor of worse 2-year scores for function, activity, and knee pain. Preoperative opioid use and TMEs were neither independent predictors of met expectations, satisfaction, patient-perceived improvement, nor improvement on any PROs. Our findings demonstrate that preoperative opioid use is associated with clinically relevant worse patient-reported knee function and pain after knee surgery.

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