scholarly journals Adaptive Information Assimilation using Convolutional Neural Network for Forecast of Breast Cancer from Electronic Health Records

2019 ◽  
Author(s):  
Senthil Kumar Kumar J ◽  
Kamala Devi K ◽  
Raja Sekar J

Abstract Purpose Data acquired from cancer based Electronic Health Records (EHRs) shows key statistics on cancer affected persons. To estimate the impact of the cancer on those persons, we need to extract vital information from those pathology health records. It is an exhaustive procedure to carry out because of large volume of records and data acquired for a continuous period of time.Methods This research portrays, the investigation of convolutional neural network (CNN) and Support Vector Machine (SVM) techniques for extracting topographic codes from the pathology reports of breast cancer. Investigations are carried out using conventional frequency vector space method and the deep learning techniques such as CNN. The learning experience of those algorithms were absorbed on a set of 730 pathology reports.Results We perceived that the CNN technique reliably outperformed the conventional frequency vector methods. It is also observed that it causes the micro and macro average performance to increase up to 0.119, and 0.101, while considering the populated class labels for the CNN model. Unambiguously, the top performing CNN approach attained a micro-F score of 0.821 over the considered topography codes.Conclusion These promising outcomes reveals the prospective of deep learning approaches, particularly CNN for estimating the impact of the cancer from the pathology reports compared to conventional SVM approach. More advanced and accurate approaches to effectively improve the accuracy in information extraction are needed.

JMIR Cancer ◽  
10.2196/19812 ◽  
2021 ◽  
Vol 7 (4) ◽  
pp. e19812
Author(s):  
Chia-Wei Liang ◽  
Hsuan-Chia Yang ◽  
Md Mohaimenul Islam ◽  
Phung Anh Alex Nguyen ◽  
Yi-Ting Feng ◽  
...  

Background Hepatocellular carcinoma (HCC), usually known as hepatoma, is the third leading cause of cancer mortality globally. Early detection of HCC helps in its treatment and increases survival rates. Objective The aim of this study is to develop a deep learning model, using the trend and severity of each medical event from the electronic health record to accurately predict the patients who will be diagnosed with HCC in 1 year. Methods Patients with HCC were screened out from the National Health Insurance Research Database of Taiwan between 1999 and 2013. To be included, the patients with HCC had to register as patients with cancer in the catastrophic illness file and had to be diagnosed as a patient with HCC in an inpatient admission. The control cases (non-HCC patients) were randomly sampled from the same database. We used age, gender, diagnosis code, drug code, and time information as the input variables of a convolution neural network model to predict those patients with HCC. We also inspected the highly weighted variables in the model and compared them to their odds ratio at HCC to understand how the predictive model works Results We included 47,945 individuals, 9553 of whom were patients with HCC. The area under the receiver operating curve (AUROC) of the model for predicting HCC risk 1 year in advance was 0.94 (95% CI 0.937-0.943), with a sensitivity of 0.869 and a specificity 0.865. The AUROC for predicting HCC patients 7 days, 6 months, 1 year, 2 years, and 3 years early were 0.96, 0.94, 0.94, 0.91, and 0.91, respectively. Conclusions The findings of this study show that the convolutional neural network model has immense potential to predict the risk of HCC 1 year in advance with minimal features available in the electronic health records.


2020 ◽  
Author(s):  
Chia-Wei Liang ◽  
Hsuan-Chia Yang ◽  
Md Mohaimenul Islam ◽  
Phung Anh Alex Nguyen ◽  
Yi-Ting Feng ◽  
...  

BACKGROUND Hepatocellular carcinoma (HCC), usually known as hepatoma, is the third leading cause of cancer mortality globally. Early detection of HCC helps in its treatment and increases survival rates. OBJECTIVE The aim of this study is to develop a deep learning model, using the trend and severity of each medical event from the electronic health record to accurately predict the patients who will be diagnosed with HCC in 1 year. METHODS Patients with HCC were screened out from the National Health Insurance Research Database of Taiwan between 1999 and 2013. To be included, the patients with HCC had to register as patients with cancer in the catastrophic illness file and had to be diagnosed as a patient with HCC in an inpatient admission. The control cases (non-HCC patients) were randomly sampled from the same database. We used age, gender, diagnosis code, drug code, and time information as the input variables of a convolution neural network model to predict those patients with HCC. We also inspected the highly weighted variables in the model and compared them to their odds ratio at HCC to understand how the predictive model works RESULTS We included 47,945 individuals, 9553 of whom were patients with HCC. The area under the receiver operating curve (AUROC) of the model for predicting HCC risk 1 year in advance was 0.94 (95% CI 0.937-0.943), with a sensitivity of 0.869 and a specificity 0.865. The AUROC for predicting HCC patients 7 days, 6 months, 1 year, 2 years, and 3 years early were 0.96, 0.94, 0.94, 0.91, and 0.91, respectively. CONCLUSIONS The findings of this study show that the convolutional neural network model has immense potential to predict the risk of HCC 1 year in advance with minimal features available in the electronic health records.


2015 ◽  
Vol 26 (1) ◽  
pp. 60-64 ◽  
Author(s):  
Paolo Campanella ◽  
Emanuela Lovato ◽  
Claudio Marone ◽  
Lucia Fallacara ◽  
Agostino Mancuso ◽  
...  

2019 ◽  
Vol 182 ◽  
pp. 105055 ◽  
Author(s):  
Binh P. Nguyen ◽  
Hung N. Pham ◽  
Hop Tran ◽  
Nhung Nghiem ◽  
Quang H. Nguyen ◽  
...  

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