Assessment of anterior chamber configuration changes after phacoemulsification with swept-source optical coherence tomography

Abstract Background: To assess the changes of anterior chamber angle in patients with shallow anterior chamber and normal anterior chamber after phacoemulsification and intraocular lens implantation (IOL) using anterior segment swept-source optical coherence tomography (AS-SS-OCT). Methods: This was a prospective case control study; 60 eyes of 60 patients who scheduled for cataract surgery with normal intraocular pressure (IOP). Based on anterior chamber depth (ACD) and gonioscopy findings, the eyes were classified into two groups: shallow anterior chamber group with narrow angle (SAC group, 30 eyes)；and normal anterior chamber group with wide angle (NAC group, 30 eyes). Measurements of ACD, anterior chamber volume (ACV), Iris volume (IV), lens vault (LV) , angle opening distance (AOD), angle recess area (ARA), trabecular iris space area (TISA), and trabecular iris angle (TIA) were conducted in each group before and 3 months after surgery. Differences between the two groups were compared. Results: There was no significant difference in age, axial length (AL), corneal curvature, corneal diameter, IOP and IV between the SAC group and the NAC group before operation, except for the LV (p = 0.000). All angle parameters including ACD, ACV, AOD, ARA, TISA and TIA in both groups at 3 months post-surgery were significantly different from the preoperative values (p<0.01). In addition, there were significant differences in all angle parameters between two groups before and after operation (All P< 0.05). Besides, the TISA750 in superior quadrant, ACD and ACV were significantly smaller in the group of SAC than those in the group of NAC 3 months after operation (P = 0.041, 0.001 and 0.002, respectively). Conclusions: Cataract surgery can deepen anterior chamber and increase the width of anterior chamber angle in Chinese subjects, but the ACD and ACV in patients with shallow anterior chamber and narrow angle have not reached the normal level, presumably because the iris root of SAC group inserted more anteriorly than that of NAC group. Phacoemulsification may not completely eliminate the risk of glaucoma in NAC group of people after surgery.

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Assessment of anterior chamber angle changes after phacoemulsification with swept-source OCT

International Journal of Ophthalmology ◽

10.18240/ijo.2021.10.08 ◽

2021 ◽

Vol 14 (10) ◽

pp. 1527-1532

Author(s):

Qian Zheng ◽

◽

Zhang-Liang Li ◽

Ping-Jun Chang ◽

Yun-E Zhao ◽

...

Keyword(s):

Intraocular Pressure ◽

Cataract Surgery ◽

Anterior Chamber ◽

Anterior Chamber Depth ◽

Anterior Chamber Angle ◽

Swept Source ◽

Narrow Angle ◽

Significant Difference ◽

Shallow Anterior Chamber ◽

Chamber Angle

AIM: To assess the changes of anterior chamber angle in patients with shallow anterior chamber after phacoemulsification combined with intraocular lens (IOL) implantation, based on anterior segment swept-source optical coherence tomography (AS-SS-OCT) measurements. METHODS: This was a prospective case control study; sixty eyes of sixty case were scheduled for cataract surgery with normal intraocular pressure (IOP). Based on anterior chamber depth (ACD) and gonioscopy findings, the eyes were divided into two groups: group of shallow anterior chamber and narrow angle (SAC group, 30 eyes); and group of normal anterior chamber group with wide angle (NAC group, 30 eyes). Measurements of ACD, anterior chamber volume (ACV), iris volume (IV), lens vault (LV), angle opening distance (AOD), angle recess area (ARA), trabecular iris space area (TISA), and trabecular iris angle (TIA) were conducted in each group before and 3mo after surgery. RESULTS: There was no significant difference in age, axial length (AL), corneal curvature, corneal diameter, intraocular pressure, and IV between two groups before surgery, except for the LV (P=0.000). ACD and ACV were prominently larger in the NAC group than the SAC group 3mo after operation (3.69±0.38 vs 3.85±0.39 mm, P=0.025; 161.37±19.47 vs 178.26±20.30 mm3, P=0.002). AOD750, ARA750 in nasal and inferior quadrants, TISA750 in all quadrants except temporal, and TIA750 in all quadrants in SAC group were significantly smaller than those in NAC group after operation (all P<0.05). CONCLUSION: Cataract surgery can deepen anterior chamber and increase the width of anterior chamber angle in Chinese subjects, but the angle related parameters including AOD750, ARA750, TISA750, TIA, TISA750, and ACV in patients with shallow anterior chamber and narrow angle do not reach the normal level.

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Assessment of anterior chamber configuration changes after phacoemulsification with swept-source optical coherence tomography

10.21203/rs.2.9863/v1 ◽

2019 ◽

Author(s):

Man Hu ◽

Qian Zheng ◽

Zhangliang Li ◽

Pingjun Chang ◽

Yun-e Zhao

Keyword(s):

Optical Coherence Tomography ◽

Cataract Surgery ◽

Anterior Chamber ◽

Anterior Segment ◽

Anterior Chamber Depth ◽

Optical Coherence ◽

Swept Source ◽

Narrow Angle ◽

Age Related ◽

Shallow Anterior Chamber

Abstract Background To assess the changes of anterior chamber angle in patients with shallow anterior chamber and normal anterior chamber after phacoemulsification and intraocular lens implantation (IOL) using anterior segment swept-source optical coherence tomography (AS-SS-OCT). Methods This was a prospective case control study; 60 eyes of 60 patients who underwent cataract surgery. Based on anterior chamber depth (ACD) and gonioscopy findings, the eyes were classified into two groups, shallow anterior chamber group (30 eyes) and normal anterior chamber group (30 eyes). AS-SS-OCT was used to measure ACD and angle parameters angle opening distance (AOD), angle recess area (ARA), trabecular iris space area(TISA), and trabecular iris angle (TIA). Serial changes in each group were measured before and 3 months after phacoemulsification and IOL, and the differences between the two groups were compared. Results All angle parameters including ACD, AOD, ARA, TISA, and TIA in both groups at 3 months after cataract surgery were significantly different from the preoperative values (p<0.01). In addition, we found significant differences of all angle parameters between groups of shallow anterior chamber (SAC) and normal anterior chamber (NAC) (All P< 0.05). Besides, the TISA750 in superior quadrant and anterior chamber volume (ACV) were significantly smaller in the group of SAC than those in the group of NAC (P = 0.041 and 0.002, respectively). Conclusions The parameters of anterior chamber increased significantly in both two groups but not increase to the same extent 3 months after phacoemulsification. Iris thickening may also be one of the narrow angle factors,not just age-related lens thickening.

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Reproducibility of Anterior Chamber Angle Analyses With the Swept-Source Optical Coherence Tomography in Young, Healthy Caucasians

Investigative Opthalmology & Visual Science ◽

10.1167/iovs.13-12904 ◽

2014 ◽

Vol 55 (6) ◽

pp. 3999 ◽

Cited By ~ 14

Author(s):

Hellen C. S. Römkens ◽

Henny J. M. Beckers ◽

Marc Frusch ◽

Tos T. J. M. Berendschot ◽

John de Brabander ◽

...

Keyword(s):

Optical Coherence Tomography ◽

Anterior Chamber ◽

Optical Coherence ◽

Anterior Chamber Angle ◽

Swept Source ◽

Chamber Angle

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Anterior chamber angle imaging with swept-source optical coherence tomography: comparison between CASIAII and ANTERION

Scientific Reports ◽

10.1038/s41598-020-74813-3 ◽

2020 ◽

Vol 10 (1) ◽

Author(s):

Poemen Pui-man Chan ◽

Gilda Lai ◽

Vivian Chiu ◽

Anita Chong ◽

Marco Yu ◽

...

Keyword(s):

Optical Coherence Tomography ◽

Anterior Chamber ◽

Anterior Segment ◽

Anterior Chamber Depth ◽

Angle Closure ◽

Optical Coherence ◽

Anterior Chamber Angle ◽

Swept Source ◽

Scan Pattern ◽

Chamber Angle

Abstract This study compared the test–retest variabilities and measurement agreement of anterior chamber angle (ACA) dimensions measured by two anterior segment swept-source optical coherence tomography (SS-OCT)—the ANTERION (Heidelberg Engineering, Heidelberg, Germany) and CASIAII (Tomey, Nagoya, Japan). Thirty-eight subjects, 18 patients with primary angle closure and 20 healthy participants with open angles, were included. The mean age was 54.7 ± 15.8 years (range: 26–75 years). One eye of each subject was randomly selected for anterior segment imaging by ANTERION and CASIAII, using the same scan pattern (6 evenly spaced radial scans across the anterior segment for three times) in the same visit. The between- and within-instrument agreement and repeatability coefficients of angle open distance (AOD500), trabecular-iris space area (TISA500), lens vault (LV), scleral spur-scleral spur distance (SSD), anterior chamber depth (ACD), and pupil diameter (PD) were measured. The anterior and posterior boundaries of the cornea, iris, and lens were automatically segmented by the SS-OCT instruments; the scleral spur was manually located by a single masked observer. There were significant differences between ANTERION and CASIAII measurements; the SSD, PD, and ACD were smaller whereas AOD500 and TISA500 were greater in ANTERION compared with CASIAII (P < 0.001). Anterior segment measurements obtained from the two SS-OCT instruments showed strong associations (R2 ranged between 0.866 and 0.998) although the between-instrument agreement was poor; the spans of 95% limits of between-instrument agreement were ≥ 1.5-folds than the within-instrument agreement for either instrument. Whereas both SS-OCT instruments showed low test–retest measurement variabilities, the repeatability coefficients of AOD500, TISA500, ACD, and PD were slightly smaller for CASIAII than ANTERION (P ≤ 0.012).

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Investigation of anterior chamber angle by swept-source polarization sensitive optical coherence tomography

10.1117/12.808627 ◽

2009 ◽

Author(s):

Yoshiaki Yasuno ◽

Masahiro Yamanari ◽

Keisuke Kawana ◽

Masahiro Miura ◽

Shuichi Makita ◽

...

Keyword(s):

Optical Coherence Tomography ◽

Anterior Chamber ◽

Optical Coherence ◽

Anterior Chamber Angle ◽

Swept Source ◽

Chamber Angle

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Anterior Chamber Angle Imaging with Swept-Source Optical Coherence Tomography: Measuring Peripheral Anterior Synechia in Glaucoma

Ophthalmology ◽

10.1016/j.ophtha.2012.12.006 ◽

2013 ◽

Vol 120 (6) ◽

pp. 1144-1149 ◽

Cited By ~ 35

Author(s):

Isabel Lai ◽

Heather Mak ◽

Gilda Lai ◽

Marco Yu ◽

Dennis S.C. Lam ◽

...

Keyword(s):

Optical Coherence Tomography ◽

Anterior Chamber ◽

Optical Coherence ◽

Anterior Chamber Angle ◽

Swept Source ◽

Chamber Angle

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Anterior Chamber Angle Imaging with Swept-Source Optical Coherence Tomography: An Investigation on Variability of Angle Measurement

Investigative Opthalmology & Visual Science ◽

10.1167/iovs.11-7507 ◽

2011 ◽

Vol 52 (12) ◽

pp. 8598 ◽

Cited By ~ 63

Author(s):

Shu Liu ◽

Marco Yu ◽

Cong Ye ◽

Dennis S. C. Lam ◽

Christopher Kai-shun Leung

Keyword(s):

Optical Coherence Tomography ◽

Anterior Chamber ◽

Angle Measurement ◽

Optical Coherence ◽

Anterior Chamber Angle ◽

Swept Source ◽

Chamber Angle

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High-speed, swept-source optical coherence tomography: a 3-dimensional view of anterior chamber angle recession

Acta Ophthalmologica Scandinavica ◽

10.1111/j.1600-0420.2006.00836.x ◽

2006 ◽

Vol 85 (6) ◽

pp. 684-685 ◽

Cited By ~ 9

Author(s):

Keisuke Kawana ◽

Yoshiaki Yasuno ◽

Toyohiko Yatagai ◽

Tetsuro Oshika

Keyword(s):

Optical Coherence Tomography ◽

Anterior Chamber ◽

High Speed ◽

Optical Coherence ◽

Anterior Chamber Angle ◽

Swept Source ◽

3 Dimensional ◽

Angle Recession ◽

Chamber Angle

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Anterior segment optical coherence tomography imaging and ocular biometry in cataract patients with open angle glaucoma comorbidity

BMC Ophthalmology ◽

10.1186/s12886-021-01874-x ◽

2021 ◽

Vol 21 (1) ◽

Author(s):

Giedre Pakuliene ◽

Kirilas Zimarinas ◽

Irena Nedzelskiene ◽

Brent Siesky ◽

Loreta Kuzmiene ◽

...

Keyword(s):

Optical Coherence Tomography ◽

Anterior Chamber ◽

Optical Coherence ◽

Anterior Chamber Angle ◽

Swept Source ◽

Lens Position ◽

Ocular Biometry ◽

Cataract Patients ◽

Chamber Angle ◽

Glaucoma Group

Abstract Background Anterior chamber angle anatomy in perspective of ocular biometry may be the key element to intraocular pressure (IOP) reduction, especially in glaucoma patients. We aim to investigate anterior chamber angle and biometrical data prior to cataract surgery in patients with and without glaucoma comorbidity. Materials and methods This prospective comparative case-control study included 62 subjects (38 with cataract only and 24 with cataract and glaucoma). A full ophthalmic examination including, Goldmann applanation tonometry, anterior chamber swept source optical coherence tomography (DRI OCT Triton plus (Ver.10.13)) and swept source optical biometry (IOL Master 700 v1.7) was performed on all participants. Results We found that ocular biometry parameters and anterior chamber parameters were not significantly different among groups. However, when we added cut-off values for narrow angles, we found that glaucoma group tended to have more narrow angles than control group. IOP was higher in glaucoma group despite all glaucoma patients having medically controlled IOP. In all subjects, anterior chamber parameters correlated well with lens position (LP), but less with relative lens position, while LP cut-off value of 5.1 mm could be used for predicting narrow anterior chamber angle parameters. Conclusions Cataract patients tend to develop narrow anterior chamber angles. Anterior chamber angle parameters have a positive moderate to strong relationship with lens position. LP may be used predicting narrow angles.

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