Eosinophilic pneumonia induced by lettuce: A case report

Abstract Background: Lettuce (Lactuca sativa) belongs to the Composite family and is a vegetable widely consumed globally. Although lettuce is extensively cultivated and consumed, lettuce-associated occupational allergy is rarely reported. Herein, we are reporting a case of eosinophilic pneumonia induced by lettuce for the first time.Case presentation: A 56-year-old female lettuce farmer was admitted to the hospital with a low-grade fever, worsening cough, and dyspnoea. A blood test revealed eosinophilia and a high serum IgE concentration. A chest X-ray taken on admission showed an infiltrative shadow in the upper lung field. Chest CT revealed patchy ground glass opacity on the upper lung field and thickening of the bronchial wall. The bronchoalveolar lavage fluid contained 8% eosinophils. The IgG-binding proteins that reacted with the patient’s sera were identified by immunoblot analysis. She was diagnosed as lettuce induced eosinophilic pneumonia and was treated with prednisolone, and her symptoms and radiological findings improved. Wearing a mask and reducing the amount of the crop improved her symptoms the following year.Conclusions: This is the first case report about lettuce-induced eosinophilic pneumonia which occurred in a lettuce farmer. The avoidance from antigen is quite useful in this patient.

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Spinal Intradural, Extramedullary Ependymoma with Astrocytoma Component: A Case Report and Review of the Literature

Case Reports in Pathology ◽

10.1155/2016/3534791 ◽

2016 ◽

Vol 2016 ◽

pp. 1-5 ◽

Cited By ~ 2

Author(s):

Gene M. Weinstein ◽

Knarik Arkun ◽

James Kryzanski ◽

Michael Lanfranchi ◽

Gaurav K. Gupta ◽

...

Keyword(s):

Back Pain ◽

Case Report ◽

Lower Back Pain ◽

Low Grade ◽

Review Of The Literature ◽

Pathologic Evaluation ◽

Lower Back ◽

Spinal Lesions ◽

First Case ◽

Intradural Extramedullary

Ependymomas are common spinal lesions, with the vast majority arising in an intramedullary location. Several cases have been described in the literature of ependymomas in an intradural, extramedullary location. The authors present a case of a 56-year-old female who presented with several weeks of lower back pain and weakness. MRI revealed an intradural, extramedullary enhancing mass at L1-L2. The mass was successfully resected surgically. Pathologic evaluation revealed a low grade glioma with components of both ependymoma and pilocytic astrocytoma with MUTYH G382D mutation. Extramedullary ependymomas are very rare tumors. To the authors’ knowledge, this is the first case of ependymoma/astrocytoma collision tumors described in an extramedullary location.

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Gastric mixed adenoneuroendocrine carcinoma case report

SAGE Open Medical Case Reports ◽

10.1177/2050313x19828918 ◽

2019 ◽

Vol 7 ◽

pp. 2050313X1982891

Author(s):

Miguel Angel Moyón Constante ◽

Fernando Xavier Moyón Constante ◽

Jorge Fernando Tufiño ◽

Andres Cárdenas Patiño ◽

Gabriel Alejandro Molina ◽

...

Keyword(s):

Case Report ◽

World Health ◽

Low Grade ◽

Radical Gastrectomy ◽

Upper Endoscopy ◽

Mixed Adenoneuroendocrine Carcinoma ◽

First Case ◽

The World ◽

Medical Teams ◽

Health Organization

Mixed adenoneuroendocrine carcinomas are rare tumors that contain both an exocrine and an endocrine component. Since the latest classification by the World Health Organization and with the aid of immunostaining, more mixed adenoneuroendocrine carcinomas are now identified and diagnosed. Nonetheless, our knowledge of these tumors is still limited, notably concerning gastric variants, as the cases reported in the literature are very limited. The clinical and surgical treatment, including the chemotherapy schemes, the prognosis, and recurrence still represent challenges for the medical teams. We present the case of a 62-year-old woman. After an upper endoscopy revealed multiple polyps and a low-grade neuroendocrine tumor, a D2 radical gastrectomy was performed. A low output esophageal anastomotic leak was discovered in the postoperative period and successfully managed. Pathology revealed a gastric mixed adenoneuroendocrine carcinoma, the first case of this kind reported in Ecuador. Patient is doing well and under constant surveillance up until her 13th postoperative month.

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Non allergic simple eosinophilic pneumonia: Löffler syndrome: A case report study

Medicinski pregled ◽

10.2298/mpns0812643m ◽

2008 ◽

Vol 61 (11-12) ◽

pp. 643-646 ◽

Cited By ~ 2

Author(s):

Ivana Meta-Jevtovic ◽

Miroslav Tomovic ◽

Slavica Mojsilovic ◽

Marina Petrovic

Keyword(s):

Case Report ◽

Bronchial Asthma ◽

Allergic Bronchopulmonary Aspergillosis ◽

Eosinophilic Pneumonia ◽

Unknown Etiology ◽

Caucasian Woman ◽

Low Grade ◽

Radiographic Findings ◽

Therapy Regimen ◽

History Of

Introduction L?ffler syndrome is an acute, pneumonia of unknown etiology. This disease is not often associated with bronchial asthma. In its asymptomatic form, this disease is reversible, transient, self-limited with no requests for specific therapy regimen. In the symptomatic form, as well as during its progression, treatment with steroids is very effective. Furthermore, in both acute eosinophilic and idiopathic chronic eosinophilic form, this kind of therapy ensures survival. Case report The case of a 53-year-old Caucasian woman was presented with 2-month history of low grade fever, shortness of breath, cough and reduced exercise tolerance. Although she had an allergic accident on insects in history, non allergy reactions as well as an obstructive disease with that kind of origin were not detected on admission. The diagnosis of simple eosinophilic pneumonia (SEP) (L?ffler's syndrome) was confirmed by transbronchial biopsy and by sternal testing. The peripheral blood eosinophilia with pulmonary eosinophilic infiltrates on X ray chest radiography were observed during clinical examination. Biopsy specimen of the lung parenchym showed changes associated with L?ffler's syndrome. The diagnosis was, also, confirmed according to the radiographic findings of unilateral migratory infiltrates consistent pneumonia. Discussion Churg Strauss syndrome (CSS) has to be considered in this differential diagnosis. Frequently, this disease has extrinsic bronchial asthma with eosinophilic pneumonia in history; asthma is often associated with allergic bronchopulmonary aspergillosis. In the reported case, treatment with steroids resulted in a marked clinical improvement compared to nonsteroid therapy.

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Acute eosinophilic pneumonia caused by camostat mesilate: The first case report

Respiratory Medicine Case Reports ◽

10.1016/j.rmcr.2016.06.005 ◽

2016 ◽

Vol 19 ◽

pp. 21-23 ◽

Cited By ~ 4

Author(s):

Shinichiro Ota ◽

Yu Hara ◽

Soichiro Kanoh ◽

Masahiro Shinoda ◽

Shuichi Kawano ◽

...

Keyword(s):

Case Report ◽

Eosinophilic Pneumonia ◽

Camostat Mesilate ◽

Acute Eosinophilic Pneumonia ◽

First Case

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Phenobarbitone Induced Toxic Epidermal Necrosis in a Young Patient - A Rare Clinical Presentation: A Case Report and Brief Review of the Literatures

10.21203/rs.3.rs-458796/v1 ◽

2021 ◽

Author(s):

Biniyam A. Ayele ◽

Kemal Ali ◽

Eliyas Mulatu

Keyword(s):

Case Report ◽

Asthmatic Patient ◽

Wound Care ◽

Tube Feeding ◽

Whole Body ◽

Stevens Johnson Syndrome ◽

Low Grade ◽

First Case ◽

Epidermal Necrosis ◽

New Onset

Abstract Background: Toxic epidermal necrolysis (TEN)/ Stevens-Johnson syndrome (SJS) is the spectrum of severe, acute, mucocutaneous, Ig E mediated hypersensitivity reaction; universally related to different drugs. Phenobarbitone is known to cause hypersensitivity reactions with benign pattern; ranging from a mild to moderate rashes but not life-threatening reactions such as TEN/SJS. Little is known about TEN in asthmatic patient. To the best of our knowledge, this is the first case of Phenobarbitone-induced TEN in a young asthmatic patient from the sub Saharan African. Case report: We report a 14-year-old right handed asthmatic male patient who presented with extensive blister skin eruptions involving the whole body including mouth ear canal later followed by skin exfoliation associated with low grade fever, sore throat, and dysphagia. The hypersensitivity skin reaction developed two weeks after initiation of Phenobarbitone of 100mg twice daily for a new onset generalized tonic clonic seizure. The exfoliation also involved oral and Conjunctival mucosa; with estimated 65% body surface area involvement; hence the diagnosis of Toxic epidermal necrosis was made. The Laboratory investigations were relevant for mild leucocytosis, prolonged prothrombin time, and reduced albumin. Phenobarbitone was discontinued and replaced with clonazepam; and the patient was managed with fluids replacement, IV antibiotics, twice daily wound care, analgesics, and naso gastric tube feeding. On subsequent days in intensive care unit (ICU), the patients’ clinical condition started improving; the skin lesion also started to heal and exfoliate in most of the affected skin surface areas, and the patient was discharges improved after ten days of ICU care.Conclusion: In summary, the present case describes, a 14-years-old young child with history of allergy in a form of asthma and new onset seizure disorder; and developed toxic epidermal necrosis following exposure to Phenobarbitone. This case also highlighted the benign prognosis observed in paediatrics population with TEN.

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Ichthyosis Uteri: A Case Report and Review of the Literature

Archives of Pathology & Laboratory Medicine ◽

10.5858/2005-129-e124-iuacra ◽

2005 ◽

Vol 129 (5) ◽

pp. e124-e125

Author(s):

Chhanda Bewtra ◽

Qing M. Xie ◽

William J. Hunter ◽

William Jurgensen

Keyword(s):

Case Report ◽

Squamous Metaplasia ◽

Endometrial Adenocarcinoma ◽

Low Grade ◽

Review Of The Literature ◽

Endometrial Polyps ◽

Chronic Endometritis ◽

Squamous Cells ◽

First Case

Abstract Squamous metaplasia of endometrium is mostly manifested by morules or nodules of benign nonkeratinizing squamous cells intimately mixed with benign or malignant endometrial glands. It has been described with low-grade adenocarcinoma of the endometrium, as well as with various benign conditions, including hyperplasia, chronic endometritis, and endometrial polyps. However, extensive plaquelike, keratinizing squamous change is distinctly uncommon. To our knowledge, we describe the first case of extensive benign squamous keratinization with underlying endometrial adenocarcinoma.

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Primary thyroid-like low-grade nasopharyngeal papillary adenocarcinoma in a 11-year-old male patient: The first case report in Indonesia

Human Pathology Case Reports ◽

10.1016/j.ehpc.2020.200392 ◽

2020 ◽

Vol 21 ◽

pp. 200392

Author(s):

Emilia Theresia ◽

Ery Kus Dwianingsih ◽

Hanggoro Tri Rinonce ◽

Rita Cempaka ◽

Camelia Herdini ◽

...

Keyword(s):

Case Report ◽

Male Patient ◽

Papillary Adenocarcinoma ◽

Low Grade ◽

First Case

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Case Report: Response to Intra-arterial Cisplatin and Concurrent Radiotherapy Followed by Salvage Surgery in a Patient With Advanced Primary Sinonasal Low-Grade Non-intestinal Adenocarcinoma

Frontiers in Surgery ◽

10.3389/fsurg.2020.599392 ◽

2020 ◽

Vol 7 ◽

Author(s):

Hirohiko Tachino ◽

Hiromasa Takakura ◽

Hideo Shojaku ◽

Michiro Fujisaka ◽

Katsuichi Akaogi ◽

...

Keyword(s):

Case Report ◽

Salvage Surgery ◽

Histopathological Examination ◽

Locally Advanced ◽

Middle Turbinate ◽

Lymphocytic Infiltration ◽

Low Grade ◽

Fractionated Radiotherapy ◽

First Case ◽

Positron Emission

Background: The clinical usefulness of concurrent chemoradiotherapy before surgery in the treatment of primary, locally advanced sinonasal low-grade, non-intestinal type adenocarcinoma (LG non-ITAC) is unclear.Methods: We present the first case report of the efficacy of super-selective intra-arterial cisplatin (CDDP) infusion concurrent with conventional fractionated radiotherapy (RT) for LG non-ITAC in a Japanese patient.Results: A white, rugged-marginal mass that was histopathologically diagnosed as LG non-ITAC occupied the right nasal cavity. Based on the imaging findings, including computed tomography, magnetic resonance imaging, and positron emission tomography, the tumor was diagnosed as T4aN0M0, stage IVa. After treatment, the nasal tumor disappeared leaving only a small bulge in the medial wall of the middle turbinate. The patient also underwent right transnasal ethmoidectomy performed as salvage surgery. A histopathological examination revealed that the lesion was replaced by granulation tissue with lymphocytic infiltration and hemosiderin-laden macrophages, and no viable tumor cells remained. In the seven years after treatment, the patient has not experienced any local recurrence or regional or distant metastasis.Conclusions: Super-selective intra-arterial CDDP infusion concurrent with conventional fractionated RT followed by salvage surgery might be useful for the management of sinonasal LG non-ITAC.

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Radiation-Induced Low Grade Fibromyxoid Sarcoma of the Larynx: a Case Report and Literature Review

Folia Medica ◽

10.3897/folmed.53.e56150 ◽

2021 ◽

Vol 63 (3) ◽

pp. 433-437

Author(s):

Dariya Chivchibashi ◽

Pavel Pavlov ◽

Maria Tzaneva ◽

Nikolay Sapundzhiev ◽

Georgi Davidov

Keyword(s):

Case Report ◽

Latency Period ◽

Metastatic Potential ◽

Low Grade ◽

Imaging Evaluation ◽

First Case ◽

Fibromyxoid Sarcoma ◽

History Of ◽

Radiation Induced ◽

Causes And Risk Factors

Low grade fibromyxoid sarcoma (LGFMS) is an uncommon variant of fibrosarcoma with high risk of local recurrence, immense metastatic potential and frequently protracted period between tumour presentation and metastasis. This unusual malignancy rarely affects the region of the head and neck which makes cases of laryngeal LGFMS extremely infrequent. To date, LGFMS of the larynx has been scatteredly mentioned in the literature. Neither incidence nor causes and risk factors for laryngeal LGFMS have been clarified so far. To the authors’ knowledge, this is the first case report that discusses the clinical course, imaging diagnosis, histopathological evaluation and surgical approach to radiation-induced laryngeal LGFMS.We present a case of a 70-year-old man who developed a LGFMS after previous radiotherapy (RT) for squamous cell carcinoma (SCC) of the larynx. The latency period between the time of radiation exposure and the diagnosis of LGFMS was twenty-seven months. After re-confirming the diagnosis with second biopsy and extensive imaging evaluation the patient was subjected to an open partial resection of the larynx. Owing to the rarity of the tumour, there is no established protocol with follow-up recommendations.This case highlights the importance of considering the RT history of the patient in order to monitor radiotherapy-related complications, including the occurrence of LGFMS.

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Treatment of Recurrent Primary Cutaneous Mucinous Carcinoma of the Eyelid with Modified Wide Local Excision

Case Reports in Ophthalmological Medicine ◽

10.1155/2020/6668640 ◽

2020 ◽

Vol 2020 ◽

pp. 1-5

Author(s):

Stephanie M. Tillit ◽

Siva S. R. Iyer ◽

Eric J. Grieser ◽

John T. LiVecchi

Keyword(s):

Case Report ◽

Histopathological Examination ◽

Malignant Neoplasm ◽

Surgical Excision ◽

Residual Tumor ◽

Excisional Biopsy ◽

Mucinous Carcinoma ◽

Low Grade ◽

Upper Eyelid ◽

First Case

Primary cutaneous mucinous carcinoma (PCMC) is a rare, low-grade malignant neoplasm of the sweat gland, whose history has been controversial regarding eccrine versus apocrine origin. This case report describes a 53-year-old male who presented to the University of Florida, Gainesville, ophthalmology clinic and was referred to the oculoplastics service with a painless, subcentimeter mass on the lateral right upper eyelid including the canthus, consistent with recurrent primary cutaneous mucinous carcinoma of the eyelid. Four years prior, the patient had undergone excisional biopsy of the lesion in a clinic, which revealed residual tumor, but the patient deferred further surgery at the time. The patient underwent surgical excision of the mass with reconstruction without operative complications and with negative surgical margins. PCMC is difficult to diagnose clinically due to its rarity and requires a histopathological examination for confirmation of the diagnosis. This report presents the first case in the literature of primary cutaneous mucinous carcinoma in a patient with human immunodeficiency virus (HIV). With this case report, we aim to raise awareness of primary cutaneous mucinous carcinoma as a potential part of the differential diagnosis for malignant eyelid lesions, including those present in patients with HIV.

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