scholarly journals Postpartum Septic Symphysitis, a Rare Condition With Possible Long-Term Consequences: A Cohort Study With Long-Term Follow-Up

2021 ◽  
Author(s):  
Helen Elden ◽  
Monika Fagevik Olsen ◽  
Nasrin Farah Hussein ◽  
Lisa Wibeck Axelsson ◽  
Verena Sengpiel ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Risk Factors ◽  
Health Related Quality ◽  
Related Quality ◽  
Long Term Follow Up ◽  
Health Related ◽  
Long Term Consequences

Abstract BackgroundPostpartum septic symphysitis (PPSS) is defined as acute onset of severe pain around the symphysis, restricted movement, fever and elevated inflammatory parameters. It is a rare but serious condition requiring urgent diagnosis and treatment. The aim of this study was to describe the incidence, symptoms, diagnosis, treatment and long-term follow-up of PPSS.MethodsThis was a follow-up study including 19 women diagnosed with PPSS from 1989 to 2017 at one tertiary care hospital in Sweden. Clinical data were retrieved from hospital records and compared to those retrieved from a regional registry. Women completed a postal questionnaire, and those who reported lumbo-pelvic pain (LPP) were offered a clinical examination.Results1) PPSS was diagnosed after a normal postpartum period of 24 to 50 hours by blood tests (n=19); MRI, (n=13/19); ultrasonography (n=8 /19) or CT (n=3/19). Treatment included aspiration of symphyseal abscesses, i.v. antibiotics and physiotherapy. Women with PPSS more frequently were primiparous (n=14/19, p=0.001), had an instrumental delivery (n=14/19, p=0.003), had a longer time of active labour (p=0.01) and second stage of labour (p=0.001) than women in the regional registry. 2) Ten out of nineteen (52%) women reported LPP at follow-up. These women more often suffered impaired function related to LPP (Pelvic Girdle Questionnaire, 27 versus 0, p<0.0001), a poorer health-related quality of life (EuroQol-5 dimensions p=0.001 and EuroQol-visual analogue scale, 65 mm versus 84 mm, p=0.022) and higher levels of anxiety and depression (Hospital Anxiety Depression Scale (HADS)-A, 7 versus 2, p=0.010; and HADS-D, 1 versus 0, p=0.028) than women with no pain. 3). Of the eight women who received a clinical assessment, one had lumbar pain and seven had PGP.ConclusionsIn the largest cohort of patients with PPSS to date, primiparas and women with instrumental vaginal delivery were overrepresented, indicating that first and complicated deliveries might be risk factors. Approximately half of the women reported PGP, with considerable consequences affecting health-related quality of life and function decades after delivery. Prospective multicentre studies are needed to establish risk factors for, long-term consequences of and adequate treatment for this rare pregnancy complication.

scholarly journals Postpartum septic symphysitis, a rare condition with possible long-term consequences: a cohort study with long-term follow-up

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Helen Elden ◽  
Monika Fagevik Olsen ◽  
Nasrin Farah Hussein ◽  
Lisa Wibeck Axelsson ◽  
Verena Sengpiel ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Risk Factors ◽  
Health Related Quality ◽  
Related Quality ◽  
Long Term Follow Up ◽  
Health Related ◽  
Long Term Consequences

Abstract Background Postpartum septic symphysitis (PPSS) is defined as acute onset of severe pain around the symphysis, restricted movement, fever, and elevated inflammatory parameters. It is a rare but serious condition requiring urgent diagnosis and treatment. The aim of this study was to describe the incidence, symptoms, diagnosis, treatment, and long-term follow-up of PPSS. Methods This follow-up study included 19 out of 21 women diagnosed with PPSS from 1989 to 2017 at one tertiary care hospital in Sweden. Clinical data were retrieved from hospital records and compared to those retrieved from a regional registry. Women completed a postal questionnaire, and those who reported lumbopelvic pain (LPP) were offered a clinical examination. Results 1) PPSS was diagnosed after a normal postpartum period of 24 to 50 h by blood tests (n = 19/19), ultrasonography (n = 9 /19), computer tomography (n = 8/19) or magnetic resonance imaging (n = 16/19) Treatment included aspiration of symphyseal abscesses, i.v. antibiotics and different physiotherapeutic interventions. Women with PPSS more frequently were primiparous (n = 14/19, p = 0.001), had an instrumental delivery (n = 14/19, p = 0.003), longer time of active labour (p = 0.01) and second stage of labour (p = 0.001) than women in the regional registry. 2) Ten out of 19 (52%) women reported LPP at follow-up. These women more often suffered impaired function related to LPP (Pelvic Girdle Questionnaire, 27 versus 0, p < 0.0001), a poorer health-related quality of life (EuroQol-5 dimensions p = 0.001 and EuroQol-visual analogue scale, 65 mm versus 84 mm, p = 0.022) and higher levels of anxiety and depression (Hospital Anxiety Depression Scale (HADS) HADS-Anxiety, 7 versus 2, p = 0.010; and HADS-Depression, 1 versus 0, p = 0.028) than women with no pain. 3). Of the eight women who were clinically assessed, one had lumbar pain and seven had pelvic girdle pain (PGP). Conclusions In the largest cohort of patients with PPSS to date, primiparas and women with instrumental vaginal delivery were overrepresented, indicating that first and complicated deliveries might be risk factors. Approximately half of the women reported PGP at follow-up, with considerable consequences affecting health-related quality of life and function decades after delivery. Prospective multicentre studies are needed to establish risk factors, long-term consequences, and adequate treatment for this rare pregnancy complication.

Early and late-recorded predictors of health-related quality of life of burn patients on long-term follow-up

Burns ◽  
2019 ◽  
Vol 45 (6) ◽  
pp. 1300-1310 ◽  
Author(s):  
David Gojowy ◽  
Martin Kauke ◽  
Tobias Ohmann ◽  
Heinz-Herbert Homann ◽  
Lijo Mannil
Keyword(s):  
Quality Of Life ◽  
Burn Patients ◽  
Health Related Quality ◽  
Related Quality ◽  
Long Term Follow Up ◽  
Health Related

scholarly journals Long Term Follow-up Data and Health-Related Quality of Life in Frontline Therapy of Fit Patients Treated With FCR Versus BR (CLL10 Trial of the GCLLSG)

HemaSphere ◽  
2020 ◽  
Vol 4 (1) ◽  
pp. e336 ◽  
Author(s):  
Nadine Kutsch ◽  
Jasmin Bahlo ◽  
Sandra Robrecht ◽  
Jeremy Franklin ◽  
Can Zhang ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Health Related Quality ◽  
Related Quality ◽  
Long Term Follow Up ◽  
Health Related ◽  
Frontline Therapy

scholarly journals Spouses of Stroke Survivors Report Reduced Health-Related Quality of Life Even in Long-Term Follow-Up

Stroke ◽  
2015 ◽  
Vol 46 (9) ◽  
pp. 2584-2590 ◽  
Author(s):  
Josefine Persson ◽  
Lukas Holmegaard ◽  
Ingvar Karlberg ◽  
Petra Redfors ◽  
Katarina Jood ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Stroke Survivors ◽  
Health Related Quality ◽  
Related Quality ◽  
Long Term Follow Up ◽  
Health Related

scholarly journals Health-related quality of life of COVID-19 survivors at 6 months after hospital discharge: a cohort study

2021 ◽  
Author(s):  
MeiXuan Lin ◽  
Liqun Huang ◽  
Danwen Zheng ◽  
Linjie Zhang ◽  
Bing Feng ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Risk Factors ◽  
Cognitive Function ◽  
Health Related Quality ◽  
Sf 36 ◽  
Related Quality ◽  
Health Related

Abstract Background: COVID-19 is a multi-systemic disease that is highly contagious and pathogenic. The long-term consequences of it are not yet clear, as is whether society and life can return to a healthy state. Long-term assessment of their health-related quality of life (HRQoL) is essential. This study aimed to investigate HRQoL and its risk factors in COVID-19 survivors at a follow-up of 6-month. Methods: A multicenter cross-sectional survey was conducted among 192 COVID-19 patients with confirmed age ≥ 18 years who were discharged from various hospitals in Wuhan from January to April 2020. The demographic characteristics, clinical characteristics, and laboratory results of the study subjects were obtained from the hospital's medical records. Survivors' HRQoL was assessed using the Short Form 36 (SF-36), cognition was assessed using the ascertain dementia eight-item informant questionnaire (AD8), and survivors' pulmonary function were examined. All participants in this study completed the survey and testing at Hubei Provincial Hospital of Chinese and Western Medicine. SF-36 scores were compared with the Chinese norm, and logistic regression and multivariate analysis were used to investigate the factors affecting HRQoL in COVID-19 survivors. Results: SF-36 showed significant differences in HRQoL between COVID-19 survivors and the general Chinese population ( P< 0.05).Multiple linear regression demonstrated that age was negatively correlated with physical functioning (PF), role-physical limitation (RP) and social functioning (SF) ( P <0.05). Bodily pain (BP), vitality (VT), SF and role-emotional limitation (RE) were negatively correlated with females ( P <0.05). Length from discharge to follow‐up was positively correlated with PF and RP ( P <0.05). Abnormal cognitive function was negatively correlated with PF, RP, general health (GH), VT, SF, RE and mental health (MH) ( P <0.05). Abnormal Carbon Monoxide Diffusing Capacity (DLCO%<80%) was significantly negatively correlated with PF and SF ( P <0.05).In addition, there was a significant negative correlation between Coronary heart disease and RP, GH, VT and RE ( P <0.05).Logistic regression analysis demonstrated that age(OR 1.032) and AD8 scores (OR 1.203)were risk factors associated with a low physical component summary (PCS) score. Length from discharge to follow‐up (OR 0.971) was the protective factor for PCS score. Abnormal cognitive function (OR 1.543) was a significant determinant associated with a mental component summary (MCS)<50 in COVID-19 patients. Conclusions: The HRQoL of COVID-19 survivors remains to be improved at six-month follow-up. Future studies should track HRQoL in older adults, women, patients with abnormal DLCO, and abnormal cognitive function for a long time and provide them with rehabilitation advice and guidance.

Dysphagia and health-related quality of life in patients with eosinophilic esophagitis: a long-term follow-up

2015 ◽  
Vol 272 (12) ◽  
pp. 3833-3839 ◽  
Author(s):  
Helen Larsson ◽  
Karin Bergman ◽  
Caterina Finizia ◽  
Leif Johansson ◽  
Mogens Bove ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Eosinophilic Esophagitis ◽  
Health Related Quality ◽  
Related Quality ◽  
Long Term Follow Up ◽  
Health Related

P197 LONG-TERM HEALTH-RELATED QUALITY OF LIFE AFTER BENIGN ESOPHAGEAL PERFORATION

2019 ◽  
Vol 32 (Supplement_2) ◽  
Author(s):  
Knepper Laura ◽  
Brinkmann Sebastian ◽  
F Fuchs Hans ◽  
H Hoelscher Arnulf ◽  
Kuhr Kathrin ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Esophageal Perforation ◽  
Health Related Quality ◽  
Long Term Outcome ◽  
Related Quality ◽  
Long Term Follow Up ◽  
Health Related

Abstract Aim This study aims to evaluate long-term outcome and health related quality of life in patients with benign esophageal perforations. Background and Methods Esophageal perforation is associated with high morbidity and mortality. In addition to surgical treatment, endoscopic endoluminal stent placement and endoscopic vacuum therapy (EVT) are established methods in the management of this emergency condition. As health-related quality of life (HRQoL) is becoming a major issue in the evaluation of any therapeutic intervention not much is known about HRQoL, particular in the long-term follow-up of patients treated for benign esophageal perforation with different treatment strategies. Patients treated for benign esophageal perforation at the University Hospital Cologne from January 2003 to December 2014 were therefore investigated. Primary outcome and management of esophageal perforation were documented and long-term quality of life was assessed using the Gastrointestinal Quality of Life Index (GIQLI), the Health-Related Quality of Life Index (HRQL) for patients with gastroesophageal reflux disease (GERD) and the European Organization for Research and Treatment of Cancer (EORTC) questionnaires for general and esophageal cancer specific QoL (QLQ-C30 and QLQ-OES18). Results Patients were divided based on primary treatment into an endoscopic (46.5%), surgical (34.5%) and conservative treatment group (19%). Short- and long-term outcome, as well as quality of life were compared. HRQoL was measured after a median follow-up of 49 months. HRQoL was generally reduced in patients with benign esophageal perforation. Endoscopically treated patients showed the highest GIQLI overall score and highest EORTC general health status, followed by the conservative and the surgical group. Conclusion HRQoL in patients with benign esophageal perforation is reduced even in the long-term follow-up. Temporary stent or EVT is effective and provides a good alternative to surgery not only in the short-term but also in the long-term follow-up.

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