Primary Intraosseous Carcinoma in the Pediatric Mandible

Abstract Background: Primary intraosseous carcinoma (PIOC) is a rare malignant odontogenic tumor that predominantly occurs in males older than 50 years. PIOC can be misdiagnosed as odontogenic cyst because it occasionally shows well-defined border on radiography. In this study, a case of a 14-year-old female with PIOC who was misdiagnosed with odontogenic cyst clinically is reported along with a literature review of pediatric PIOC cases.Case Presentation: A 14-year-old female patient presented with painful swelling on the mandibular right premolar area. There was a radiolucent lesion with a well-defined border in panoramic view. She was diagnosed with odontogenic cyst, and the cystic mass was enucleated with extraction. However, the biopsy result was consistent with PIOC. After cancer work-up, she underwent partial mandibulectomy, selective neck dissection, and reconstruction with a fibular free flap. Although the surgical resection margins were clear, local recurrence and lung metastasis occurred four months after surgery. She underwent concurrent chemo-radiation therapy, but the prognosis was poor.Conclusions: PIOC should be diagnosed differentially from odontogenic cyst even in pediatric populations.

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Primary intraosseous carcinoma of the mandible with probable origin in an odontogenic cyst

Oral Surgery Oral Medicine Oral Pathology ◽

10.1016/0030-4220(89)90014-5 ◽

1989 ◽

Vol 67 (6) ◽

pp. 716-724 ◽

Cited By ~ 85

Author(s):

Charles A. Waldron ◽

Thomas A. Mustoe

Keyword(s):

Odontogenic Cyst ◽

Probable Origin ◽

Intraosseous Carcinoma

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A Large Glandular Ordontogenic Cyst of the Mandible: Report of Case

The Journal of Contemporary Dental Practice ◽

10.5005/jcdp-4-1-53 ◽

2003 ◽

Vol 4 (1) ◽

pp. 53-58 ◽

Cited By ~ 8

Author(s):

Metin Güngörmüş ◽

Ümit Ertaş ◽

M. Cemil Büyükkurt ◽

Ömer Kaya

Keyword(s):

Case Reports ◽

Clinical Findings ◽

Odontogenic Cyst ◽

Radiographic Examination ◽

Health History ◽

Glandular Odontogenic Cyst ◽

Edentulous Mandible ◽

Radiolucent Lesion ◽

The Right ◽

Excised Tissue

Abstract Glandular odontogenic cyst (GOC) is generally considered uncommon, but several investigators claim there is a more frequent occurrence than previously thought. However these case reports lacked confirming data to validate their claim. On the other hand, it is possible that cases of central mucepidermoid carcinoma or later periodontal cyst might be viewed as glandular odontogenic cyst. This is a report of a case of a 70-year old male who presented with a firm swelling in the right side of his edentulous mandible. Radiographic examination revealed a multilocular radiolucent lesion in the mandible extending from the right first premolar to the left second premolar and reaching the inferior mandible. Clinical findings, the health history, and microscopic examination of excised tissue confirmed the diagnosis of GOC. The lesion was excised and post-operative healing was uneventful. Citation Ertas Ü, Büyükkurt MC, Güngörmüs M, et.al. A Large Glandular Odontogenic Cyst of the Mandible: Report of Case. J Contemp Dent Pract 2003 February;(4)1:053-058.

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Primary intraosseous carcinoma arising in orthokeratinized odontogenic cyst

Journal of Dental Sciences ◽

10.1016/j.jds.2020.03.009 ◽

2020 ◽

Vol 15 (3) ◽

pp. 393-395

Author(s):

Chih-Huang Tseng ◽

Wen-Chen Wang ◽

Chung-Ho Chen ◽

Yuk-Kwan Chen

Keyword(s):

Odontogenic Cyst ◽

Orthokeratinized Odontogenic Cyst ◽

Intraosseous Carcinoma

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Primary intraosseous carcinoma arising from an odontogenic cyst: A case report

Oncology Letters ◽

10.3892/ol.2014.2248 ◽

2014 ◽

Vol 8 (3) ◽

pp. 1265-1268 ◽

Cited By ~ 5

Author(s):

MAKOTO ADACHI ◽

TOSHIHIRO INAGAKI ◽

YUICHI EHARA ◽

MUNEHIRO AZUMA ◽

AYUMI KURENUMA ◽

...

Keyword(s):

Case Report ◽

Odontogenic Cyst ◽

Intraosseous Carcinoma

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The Radiologic Work-up in Thyroid Surgery: Fine-needle Biopsy versus Scintigraphy and Ultrasound

Ear Nose & Throat Journal ◽

10.1177/014556130208100309 ◽

2002 ◽

Vol 81 (3) ◽

pp. 151-154 ◽

Cited By ~ 17

Author(s):

Stilianos E. Kountakis ◽

Ioannis G. Skoulas ◽

A.A.J. Maillard

Keyword(s):

Medical Records ◽

Fine Needle Biopsy ◽

Needle Aspiration ◽

Cystic Mass ◽

High Rate ◽

Thyroid Scintigraphy ◽

Fine Needle ◽

Work Up ◽

Positive Results ◽

Thyroid Lesions

To compare the effectiveness and predictive value of radiologic studies with fine-needle aspiration biopsy (FNAB) in correctly diagnosing thyroid lesions, we reviewed the medical records of 441 patients who had been treated surgically for thyroid disease from 1987 through 1999. We compared the results of thyroid scintigraphy, ultrasound, and FNAB with findings on final surgical pathology. The data were analyzed according to the chisquared (χ2) test. Of 189 thyroid scintigraphy scans that showed a hypofunctional (cold) nodule, 52 (27.5%) were found to be cancerous, and of 35 hyperfunctional (hot) nodules, two (5.7%) were malignant (sensitivity = 91 %; specificity = 19%; accuracy = 38%; χ2 = 7.67; p = 0.006). Of 66 ultrasounds that detected a solid or a mixed solid-cystic mass, 16 (24.2%) were cancerous, while none of the eight sonograms that showed a purely cystic lesion was malignant (sensitivity = 100%; specificity = 14%; accuracy = 32%; χ2 = 2.47; p = 0.116 [not statistically significant]). Of the 119 patients whose FNABs were diagnostic, 55 biopsies revealed follicular cells. Of the remaining 64 biopsies, cancer was correctly predicted in 35 of 44 patients (79.5%) and benign disease was correctly diagnosed in 18 of 20 patients (90.0%) (sensitivity = 95%; specificity = 67%; accuracy = 83%; χ2 = 27.3; p = 0.00). We conclude that in the evaluation of thyroid lesions, FNAB is superior to imaging studies, which yield a relatively high rate of false-positive results.

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Glandular Odontogenic Cystin Maxilla : A Case Series

Journal of Nepal Medical Association ◽

10.31729/jnma.3614 ◽

2018 ◽

Vol 56 (211) ◽

pp. 705-707 ◽

Cited By ~ 1

Author(s):

Bidhata Ojha ◽

Dipshikha Bajracharya ◽

Radha Baral ◽

Shubrata Bhattacharyya ◽

Saurabh Roy ◽

...

Keyword(s):

Case Series ◽

Immunohistochemical Analysis ◽

Final Diagnosis ◽

Odontogenic Cyst ◽

Growth Potential ◽

High Rate ◽

Jaw Cysts ◽

Histopathological Features ◽

Glandular Odontogenic Cyst ◽

Radiolucent Lesion

Glandular odontogenic cyst is rare phenomenon with 0.012% to 0.03. 3% frequency of all jaw cysts and worldwide prevalence of 0.17%. Diagnosis of Glandular odontogenic cyst, well known for its aggressive growth potential and high rate of recurrence, is very crucial. This report presents cases of two 50-year old individuals with Glandular odontogenic cyst presenting as a radiolucent lesion of maxilla. Final diagnosis was made on the basis of histopathological features and further confirmed by immunohistochemical analysis.

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An Unusual Case of Paraganglioma of the Broad Ligament Presenting as Cystic Mass

Case Reports in Pathology ◽

10.1155/2016/1041989 ◽

2016 ◽

Vol 2016 ◽

pp. 1-4

Author(s):

Siddhi Gaurish Sinai Khandeparkar ◽

Maithili Mandar Kulkarni ◽

Vandana Gaopande ◽

Avinash Joshi ◽

Pushpalata Naphade

Keyword(s):

Clinical Practice ◽

Unusual Case ◽

Broad Ligament ◽

Cystic Mass ◽

Accurate Diagnosis ◽

Rare Entity ◽

High Degree ◽

Work Up ◽

Postmenopausal Female

In clinical practice, broad ligament (BL) tumors are seldom encountered. Paraganglioma of the BL is exceedingly rare entity. Here we present an unusual case of broad ligament paraganglioma, presenting as a cystic mass, in a 50-year-old postmenopausal female. A high degree of suspicion along with detailed immunohistopathological work-up is needed for arriving at an accurate diagnosis.

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Recurrent Enlarging Mesenteric Desmoid Tumor following Remote Surgical Resection

Case Reports in Radiology ◽

10.1155/2017/2312617 ◽

2017 ◽

Vol 2017 ◽

pp. 1-5 ◽

Cited By ~ 3

Author(s):

Connie Hapgood ◽

Allison DeLong

Keyword(s):

Surgical Resection ◽

Desmoid Tumor ◽

Tissue Characterization ◽

Treatment Options ◽

Resection Margins ◽

Desmoid Tumors ◽

Genetic Syndromes ◽

Preoperative Work Up ◽

Work Up ◽

Ct And Mri

Intra-abdominal desmoid tumors are commonly associated with genetic syndromes such as familial polyposis coli. Radiological cross imaging studies such as CT and MRI are used in the preoperative work-up of such tumors. Postoperatively, CT and MRI are useful in the assessment of recurrent desmoid tumors. MRI is more accurate in tissue characterization. Where possible, surgical resection remains the standard first-line treatment. For patients where surgery is not possible, or the resection margins are not clear, other forms of treatment are possible. These include hormonal and nonhormonal options. We present a case of a recurrent sporadic intra-abdominal (mesenteric) desmoid tumor. Such an entity is rare with few cases reported in the literature. Treatment options regarding intra-abdominal desmoid tumors will be discussed.

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