scholarly journals Time-restricted feeding and lower-extremity functioning in community-dwelling older adults

2020 ◽  
Author(s):  
Daniela B. Estrada-DeLeón ◽  
Ellen A Struijk ◽  
Francisco Félix Caballero ◽  
Mercedes Sotos Prieto ◽  
Fernando Rodríguez-Artalejo ◽  
...  
Keyword(s):  
Older Adults ◽  
Lower Extremity ◽  
Large Population ◽  
Community Dwelling ◽  
Intermittent Fasting ◽  
Restricted Feeding ◽  
Lower Extremity Function ◽  
Balance Impairment ◽  
Fasting Time ◽  
Community Dwelling Older Adults

Abstract Background: Time-restricted feeding, a specific form of intermittent fasting, has been associated with several possible health benefits including improved body composition, blood lipid levels and extended lifespan. However, it is unknown if time-restricted feeding confers a protective effect on the physical function of older adults. The aim of this study was to assess time-restricted feeding in association with performance-based lower-extremity function (LEF) in a large population of community-dwelling older adults.Methods: Cross-sectional study among 1,226 individuals ≥64 years from the Seniors-ENRICA-II cohort. In 2016-2017, habitual diet was assessed through a validated diet history. Fasting time was classified into the following categories: ≤9, 10-11, and ≥12hours/day, the latter being considered time-restricted feeding. Performance-based LEF was assessed with the Short Physical Performance Battery (SPPB).Results: After adjusting for potential confounders, a longer fasting period was associated with a higher likelihood of impaired LEF [odds ratio (OR) and 95% confidence intervals (CI) for the second and third categories: 2.27 (1.56-3.33); and 2.70 (1.80-4.04), respectively, considering the ≤9 hours/day fasting group as the reference category; p-trend <0.001]. When assessing each SPPB subtest separately, fasting time showed a significant association with balance impairment (OR for highest vs. lowest fasting time: 2.48; 95% CI: 1.51-4.08; p-trend= 0.001) and difficulty to rise from a chair (OR for highest vs. lowest fasting time: 1.47; 95% CI: 1.05-2.06; p-trend= 0.01).Conclusions: Time-restricted feeding was associated with a higher likelihood of impaired LEF, balance impairment, and difficulty to rise from a chair in older adults. These results need to be confirmed in further longitudinal studies.Trial registration: ClinicalTrials.gov NCT03541135. Registered 30 May 2018, retrospectively registered.

scholarly journals Prolonged nightly fasting and lower-extremity functioning in community-dwelling older adults

2020 ◽  
pp. 1-26
Author(s):  
Daniela B. Estrada-deLeón ◽  
Ellen A. Struijk ◽  
Francisco Félix Caballero ◽  
Mercedes Sotos Prieto ◽  
Fernando Rodríguez-Artalejo ◽  
...  
Keyword(s):  
Physical Activity ◽  
Older Adults ◽  
Lower Extremity ◽  
Large Population ◽  
Community Dwelling ◽  
Lower Extremity Function ◽  
Fasting Period ◽  
Balance Impairment ◽  
Fasting Time ◽  
Community Dwelling Older Adults

Abstract It is unknown if time-restricted feeding confers a protective effect on the physical function of older adults. The aim of this study was to assess prolonged nightly fasting in association with performance-based lower-extremity function (LEF) in a large population of community-dwelling older adults. A cross-sectional study was carried out among 1,226 individuals ≥64 years from the Seniors-ENRICA-II cohort. In 2016-2017, habitual diet was assessed through a validated diet history. Fasting time was classified into the following categories: ≤9, 10-11, and ≥12hours/day, the latter being considered prolonged nightly fasting. Performance-based LEF was assessed with the Short Physical Performance Battery (SPPB). After adjusting for potential confounders, a longer fasting period was associated with a higher likelihood of impaired LEF [odds ratio (OR) and 95% confidence intervals (CI) for the second and third categories: 2.27 (1.56-3.33) and 2.70 (1.80-4.04), respectively, considering the ≤9 hours/day fasting group as reference; p-trend <0.001]. When assessing each SPPB subtest separately, fasting time showed a significant association with balance impairment (OR for highest vs. lowest fasting time: 2.48; 95% CI: 1.51-4.08; p-trend =0.001) and difficulty to rise from a chair (OR for highest vs. lowest fasting time: 1.47; 95% CI: 1.05-2.06; p-trend =0.01). The risk associated with ≥12 h fasting among those with the lowest levels of physical activity was three times higher than among those with ≤9 hours fasting with the same low level of physical activity. Prolonged nightly fasting was associated with a higher likelihood of impaired LEF, balance impairment, and difficulty to rise from a chair in older adults, especially among those with low levels of physical activity.

scholarly journals Time-restricted feeding and lower-extremity functioning in community-dwelling older adults

2020 ◽  
Vol 40 ◽  
pp. 684
Author(s):  
D.B. Estrada-deLeón ◽  
E.A. Struijk ◽  
F.F. Caballero ◽  
M. Sotos Prieto ◽  
F. Rodríguez-Artalejo ◽  
...  
Keyword(s):  
Older Adults ◽  
Lower Extremity ◽  
Community Dwelling ◽  
Restricted Feeding ◽  
Community Dwelling Older Adults

scholarly journals Meaningful Change Estimates for the Late-Life Function and Disability Instrument in Older Adults

2018 ◽  
Vol 74 (4) ◽  
pp. 556-559 ◽  
Author(s):  
Marla K Beauchamp ◽  
Rachel E Ward ◽  
Alan M Jette ◽  
Jonathan F Bean
Keyword(s):  
Older Adults ◽  
Lower Extremity ◽  
Community Dwelling ◽  
Minimal Detectable Change ◽  
Global Rating ◽  
Mobility Limitations ◽  
Meaningful Change ◽  
Patient Reported ◽  
Community Dwelling Older Adults ◽  
Life Function

Abstract Background The Late-Life Function and Disability Instrument (LLFDI) is a well-validated and frequently used patient-reported outcome for older adults. The aim of this study was to estimate the minimal clinically important difference (MCID) of the LLFDI-Function Component (LLFDI-FC) and its subscales among community-dwelling older adults with mobility limitations. Methods We performed a secondary analysis of the Boston Rehabilitative Impairment Study of the Elderly, a longitudinal cohort study of older adults with mobility limitations residing in the community. The MCID for each LLFDI-FC scale over 1 year of follow-up was estimated using both anchor- and distribution-based methods, including mean change scores on a patient-reported global rating of change in function scale, the standard error of measurement (SEM), and the minimal detectable change with 90% confidence (MDC90). Results Data from 320 older adults were used in the analysis (mean age 76 years, 69% female, mean of four chronic conditions). Meaningful change estimates for “small change” based on the global rating of change and SEM were 2, 3, 4, and 4 points for the LLFDI-FC overall function scale and basic lower-extremity, advanced lower-extremity, and upper-extremity subscales, respectively. Estimates for “substantial change” based on the global rating of change and minimal detectable change with 90% confidence were 5, 6, 9, and 10 points for the overall function scale and basic lower-extremity, advanced lower-extremity, and upper-extremity subscales, respectively. Conclusion This study provides the first MCID estimates for the LLFDI-FC, a widely used patient-reported measure of function. These values can be used to interpret the outcomes of longitudinal investigations of functional status in similar populations of community-dwelling older adults.

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