scholarly journals Continuous Endometrial Volumetric Analysis for Endometrial Receptivity Assessment on Assisted Reproductive Technology Cycles

2020 ◽  
Author(s):  
Renato Martins ◽  
Antonio Helio Oliani ◽  
Denise Vaz Oliani ◽  
Jose Martinez de Oliveira
Keyword(s):  
Assisted Reproductive Technology ◽  
Transvaginal Ultrasound ◽  
Continuous Process ◽  
Volume Ratio ◽  
Volumetric Analysis ◽  
Reproductive Technology ◽  
Endometrial Receptivity ◽  
Complex Process ◽  
Endometrial Pattern ◽  
Endometrial Volume

Abstract Background: Human implantation is a complex process requiring synchrony between a healthy embryo and a functionally competent or receptive endometrium. In order to assess endometrial receptivity in Assisted Reproductive Technology (ART) cycles serial evaluation of endometrial volumetric analysis may have a predictive value on a positive outcome.Methods: Serial 3D transvaginal ultrasound performed in women on ART cycle to evaluate a pattern that better predicts implantation rates. Prospective case control study of 169 subjects were assessed. Endometrial pattern, thickness, volume and adjusted endometrial volume (ratio between endometrial volume and uterine volume) was performed to all subjects on a continuous process from baseline (prior to ovarian controlled stimulation), day 6, 8 and 10 of controlled ovarian stimulation, trigger day with human chorionic gonadotropin hormone (hCG) and at embryo transfer day.Results: No statistical difference was noted between the two groups in terms of demographics and ART procedures and scores. Endometrial morphology also didn’t show any difference between the two groups. Endometrial volume and adjusted endometrial volume was significantly higher in the positive group as soon as day 6 of ovarian controlled stimulation.Conclusions: Serial 3D endometrial volume and adjusted endometrial volumes may be a useful tool for clinicians in predicting endometrial receptivity enhancing elective embryo transfers in fresh ART cycle, and thus providing a non-invasive continuous technique for endometrial receptivity assessment that reflects endometrial changes during ART procedures.

scholarly journals Continuous endometrial volumetric analysis for endometrial receptivity assessment on assisted reproductive technology cycles

2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Renato Silva Martins ◽  
António Helio Oliani ◽  
Denise Vaz Oliani ◽  
José Martinez de Oliveira
Keyword(s):  
Assisted Reproductive Technology ◽  
Transvaginal Ultrasound ◽  
Continuous Process ◽  
Embryo Implantation ◽  
Volume Ratio ◽  
Volumetric Analysis ◽  
Reproductive Technology ◽  
Endometrial Receptivity ◽  
Clinical Tool ◽  
Endometrial Volume

Abstract Background Human implantation is a complex process requiring synchrony between a healthy embryo and a functionally competent or receptive endometrium. In order to assess endometrial receptivity in Assisted Reproductive Technology (ART) cycles serial evaluation of endometrial volumetric analysis may have a predictive value on a positive outcome. Methods Serial 3D transvaginal ultrasound performed in women on ART cycle to evaluate embryo implantation predictors. Prospective case control study of 169 subjects were assessed. Endometrial pattern, thickness, volume and adjusted endometrial volume (ratio between endometrial volume and uterine volume) was performed to all subjects on a continuous process from baseline, during controlled ovarian stimulation, trigger day with human chorionic gonadotropin hormone (hCG) and at embryo transfer day. Results Demographics and ART procedures and scores, was similar between the two groups. Endometrial morphology also showed no difference between the two groups. Endometrial volume and adjusted endometrial volume was significantly higher in the positive group as soon as day 6 of ovarian controlled stimulation. Conclusions Serial 3D endometrial volume and adjusted endometrial volumes provides a predicting clinical tool enhancing elective embryo transfers in fresh ART cycle. Thus providing a non-invasive continuous technique for endometrial receptivity assessment that reflects endometrial changes during ART procedures.

scholarly journals Continuous Endometrial Volumetric Analysis for Endometrial Receptivity Assessment on Assisted Reproductive Technology Cycles

2020 ◽  
Author(s):  
Renato Martins ◽  
Antonio Helio Oliani ◽  
Denise Vaz Oliani ◽  
Jose Martinez de Oliveira
Keyword(s):  
Assisted Reproductive Technology ◽  
Endometrial Thickness ◽  
Transvaginal Ultrasound ◽  
Research Question ◽  
Continuous Process ◽  
Volume Ratio ◽  
Volumetric Analysis ◽  
Reproductive Technology ◽  
Endometrial Receptivity ◽  
Endometrial Volume

Abstract Research Question: Human implantation is a complex process requiring synchrony between a healthy embryo and a functionally competent or receptive endometrium. In order to assess endometrial receptivity in Assisted Reproductive Technology (ART) cycles continuous evaluation of endometrial volumetric analysis may have a predictive value on a positive outcome.Design: Serial 3D transvaginal ultrasound performed in women on ART cycle to evaluate a pattern that better predicts implantation rates. 169 subjects on a prospective case control study were assessed. Endometrial pattern, endometrial thickness, endometrial volume and adjusted endometrial volume (ratio between endometrial volume and uterine volume) was performed to all subjects on a continuous process from baseline (prior to ovarian controlled stimulation), day 6, 8 and 10 of controlled ovarian stimulation, trigger day with human chorionic gonadotropin hormone (hCG) and at embryo transfer day.Results: No statistical difference was noted between the two groups in terms of demographics and ART procedures and scores. Endometrium morphology also didn’t show any difference between the two groups. Endometrial volume and adjusted endometrial volume was significantly higher in the positive group as soon as day 6 of ovarian controlled stimulation.Conclusions: Continuous serial 3D endometrial volume and adjusted endometrial volumes may be a useful tool for clinicians in predicting endometrial receptivity enhancing elective embryo transfers in fresh ART cycle, and thus providing a non-invasive continuous technique for endometrial receptivity assessment that reflects endometrial changes during ART procedures.

scholarly journals Continuous Endometrial Volumetric Analysis for Endometrial Receptivity Assessment on Assisted Reproductive Technology Cycles

2020 ◽  
Author(s):  
Renato Martins ◽  
Antonio Helio Oliani ◽  
Denise Vaz Oliani ◽  
Jose Martinez de Oliveira
Keyword(s):  
Assisted Reproductive Technology ◽  
Endometrial Thickness ◽  
Transvaginal Ultrasound ◽  
Continuous Process ◽  
Volume Ratio ◽  
Positive Outcome ◽  
Volumetric Analysis ◽  
Reproductive Technology ◽  
Endometrial Receptivity ◽  
Endometrial Volume

Abstract Background: Human implantation is a complex process requiring synchrony between a healthy embryo and a functionally competent or receptive endometrium. In order to assess endometrial receptivity in Assisted Reproductive Technology (ART) cycles continuous evaluation of endometrial biophysical markers may have a predictive value on a positive outcome.Design: Serial 3D transvaginal ultrasound performed in women on ART cycle to evaluate a pattern that better predicts implantation rates. 169 subjects on a prospective case control study were assessed. Endometrial pattern, endometrial thickness, endometrial volume and adjusted endometrial volume (ratio between endometrial volume and uterine volume) was performed to all subjects on a continuous process from baseline (prior to ovarian controlled stimulation), day 6, 8 and 10 of controlled ovarian stimulation, trigger day with human chorionic gonadotropin hormone (hCG) and at embryo transfer day.Results: No statistical difference was noted between the two groups in terms of demographics and ART procedures and scores. Endometrium morphology also didn’t show any difference between the two groups. Endometrial volume and adjusted endometrial volume was significantly higher in the positive group as soon as day 6 of ovarian controlled stimulation.Conclusions: Continuous serial 3D endometrial volume and adjusted endometrial volumes may be a useful tool for clinicians in predicting endometrial receptivity enhancing elective embryo transfers in fresh ART cycle, and thus providing a non-invasive continuous technique for endometrial receptivity assessment that reflects endometrial changes during ART procedures.

scholarly journals Continuous Endometrial Volumetric Analysis for Endometrial Receptivity Assessment on Assisted Reproductive Technology Cycles

2020 ◽  
Author(s):  
Renato Martins ◽  
Antonio Helio Oliani ◽  
Denise Vaz Oliani ◽  
Jose Martinez de Oliveira
Keyword(s):  
Assisted Reproductive Technology ◽  
Transvaginal Ultrasound ◽  
Continuous Process ◽  
Embryo Implantation ◽  
Volume Ratio ◽  
Volumetric Analysis ◽  
Reproductive Technology ◽  
Endometrial Receptivity ◽  
Clinical Tool ◽  
Endometrial Volume

Abstract Background: Human implantation is a complex process requiring synchrony between a healthy embryo and a functionally competent or receptive endometrium. In order to assess endometrial receptivity in Assisted Reproductive Technology (ART) cycles serial evaluation of endometrial volumetric analysis may have a predictive value on a positive outcome. Methods: Serial 3D transvaginal ultrasound performed in women on ART cycle to evaluate embryo implantation predictors. Prospective case control study of 169 subjects were assessed. Endometrial pattern, thickness, volume and adjusted endometrial volume (ratio between endometrial volume and uterine volume) was performed to all subjects on a continuous process from baseline, during controlled ovarian stimulation, trigger day with human chorionic gonadotropin hormone (hCG) and at embryo transfer day. Results: Demographics and ART procedures and scores, was similar between the two groups. Endometrial morphology also showed no difference between the two groups. Endometrial volume and adjusted endometrial volume was significantly higher in the positive group as soon as day 6 of ovarian controlled stimulation. Conclusions: Serial 3D endometrial volume and adjusted endometrial volumes provides a predicting clinical tool enhancing elective embryo transfers in fresh ART cycle. Thus providing a non-invasive continuous technique for endometrial receptivity assessment that reflects endometrial changes during ART procedures.

scholarly journals Continuous Endometrial Volumetric Analysis for Endometrial Receptivity Assessment on Assisted Reproductive Technology Cycles

2020 ◽  
Author(s):  
Renato Martins ◽  
Antonio Helio Oliani ◽  
Denise Vaz Oliani ◽  
Jose Martinez de Oliveira
Keyword(s):  
Assisted Reproductive Technology ◽  
Transvaginal Ultrasound ◽  
Continuous Process ◽  
Embryo Implantation ◽  
Volume Ratio ◽  
Volumetric Analysis ◽  
Reproductive Technology ◽  
Endometrial Receptivity ◽  
Clinical Tool ◽  
Endometrial Volume

Abstract Background: Human implantation is a complex process requiring synchrony between a healthy embryo and a functionally competent or receptive endometrium. In order to assess endometrial receptivity in Assisted Reproductive Technology (ART) cycles serial evaluation of endometrial volumetric analysis may have a predictive value on a positive outcome.Methods: Serial 3D transvaginal ultrasound performed in women on ART cycle to evaluate embryo implantation predictors. Prospective case control study of 169 subjects were assessed. Endometrial pattern, thickness, volume and adjusted endometrial volume (ratio between endometrial volume and uterine volume) was performed to all subjects on a continuous process from baseline, during controlled ovarian stimulation, trigger day with human chorionic gonadotropin hormone (hCG) and at embryo transfer day.Results: Demographics and ART procedures and scores, was similar between the two groups. Endometrial morphology also showed no difference between the two groups. Endometrial volume and adjusted endometrial volume was significantly higher in the positive group as soon as day 6 of ovarian controlled stimulation.Conclusions: Serial 3D endometrial volume and adjusted endometrial volumes provides a predicting clinical tool enhancing elective embryo transfers in fresh ART cycle. Thus providing a non-invasive continuous technique for endometrial receptivity assessment that reflects endometrial changes during ART procedures.

Molecular markers for endometrial receptivity in assisted reproductive technology programs

2021 ◽  
Vol 11_2021 ◽  
pp. 56-62
Author(s):  
Gokhberg Ya.A. Gokhberg ◽  
Timofeeva A.V. Timofeeva ◽  
Kalinina E.A. Kalinina ◽  
Keyword(s):  
Molecular Markers ◽  
Assisted Reproductive Technology ◽  
Reproductive Technology ◽  
Endometrial Receptivity ◽  
Technology Programs

scholarly journals Endometrial Receptivity on Assisted Reproductive Technology Cycles – a correlation between Serial Serum Estradiol levels and Serial Endometrial Volume Assessment

2020 ◽  
Author(s):  
Renato Silva Martins ◽  
Antonio Helio Oliani ◽  
Denise Vaz Oliani ◽  
Jose Martinez de Oliveira
Keyword(s):  
Assisted Reproductive Technologies ◽  
Transvaginal Ultrasound ◽  
Reproductive Technologies ◽  
Endometrial Receptivity ◽  
Serum Estradiol ◽  
Biophysical Parameters ◽  
Positive Group ◽  
Serial Serum ◽  
Endometrial Volume ◽  
Estradiol Levels

Abstract Background: Diagnosis of endometrial receptivity is still unclear and conflicting. Despite advances in embryo development during assisted reproductive technologies (ART) cycles, the intricate process of implantation is still matter for debate and research. Materials and Methods: Serial serum estradiol levels and 3D transvaginal ultrasound performed in women on ART cycle to evaluate a pattern that better predicts implantation rates. 169 subjects on a prospective case control study were assessed. Serial biochemical and biophysical parameters were assessed during ovarian controlled stimulation and results compared in terms of pregnancy outcome.Results: No statistical difference was noted between the two groups in terms of demographics and ART procedures and scores. Serum estradiol was significantly higher in the positive group from day 8 after ovarian controlled stimulation. Endometrial volume and adjusted endometrial volume were significantly higher in the positive group as soon as day 6 of ovarian controlled stimulation. Conclusions: Continuous serum estradiol and 3D endometrial volume and adjusted endometrial volumes may reflect endometrial changes during ART procedures and provide a useful real time tool for clinicians in predicting endometrial receptivity.

scholarly journals Endometrial Receptivity on Assisted Reproductive Technology Cycles – a correlation between Serial Serum Estradiol levels and Serial Endometrial Volume Assessment

2020 ◽  
Author(s):  
R. Silva Martins ◽  
A. Helio Oliani ◽  
D. Vaz Oliani ◽  
J. Martinez de Oliveira
Keyword(s):  
Assisted Reproductive Technologies ◽  
Transvaginal Ultrasound ◽  
Research Question ◽  
Reproductive Technologies ◽  
Endometrial Receptivity ◽  
Serum Estradiol ◽  
Positive Group ◽  
Serial Serum ◽  
Endometrial Volume ◽  
Estradiol Levels

AbstractResearch QuestionDiagnosis of endometrial receptivity is still unclear and conflicting. Despite advances in embryo development during assisted reproductive technologies (ART) cycles, the intricate process of implantation is still matter for debate and research.DesignSerial serum estradiol levels and 3D transvaginal ultrasound performed in women on ART cycle to evaluate a pattern that better predicts implantation rates. 169 subjects on a prospective case control study were assessed. Serial biochemical and biophysical parameters were assessed during ovarian controlled stimulation and results compared in terms of pregnancy outcome.ResultsNo statistical difference was noted between the two groups in terms of demographics and ART procedures and scores. Serum estradiol was significantly higher in the positive group from day 8 after ovarian controlled stimulation. Endometrial volume and adjusted endometrial volume were significantly higher in the positive group as soon as day 6 of ovarian controlled stimulation.ConclusionsContinuous serum estradiol and 3D endometrial volume and adjusted endometrial volumes may reflect endometrial changes during ART procedures and provide a useful real time tool for clinicians in predicting endometrial receptivity.

scholarly journals Recent advances in in vitro fertilization

F1000Research ◽  
2017 ◽  
Vol 6 ◽  
pp. 1616 ◽  
Author(s):  
Robert Casper ◽  
Jigal Haas ◽  
Tzu-Bou Hsieh ◽  
Rawad Bassil ◽  
Chaula Mehta
Keyword(s):  
In Vitro Fertilization ◽  
Older Women ◽  
Assisted Reproductive Technology ◽  
Genetic Screening ◽  
Oocyte Quality ◽  
Reproductive Technology ◽  
Endometrial Receptivity ◽  
Vitro Fertilization ◽  
New Methods

The field of assisted reproductive technology is rapidly progressing with many new advances in the last decade. The present review discusses methods to improve oocyte quality in older women and new stimulation protocols that may improve the number of mature oocytes retrieved during an in vitro fertilization cycle. We will discuss the present use of pre-implantation genetic screening (PGS) and finally focus on some new methods to determine endometrial receptivity. The focus of this review is to point out areas of technology that may be controversial or are new enough to require proper controlled studies for validation.

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