Patterns Contributing to Severe Complications After Liver Resection: An Aggregate Root Cause Analysis of a Prospective Cohort
Abstract Background The Aggregate Root Cause Analysis (AggRCA) was designed to improve the understanding of system vulnerabilities contributing to patient harm, including surgical complications. It remains poorly used due to methodological complexity and resource limitations. This study aimed to identify the main patterns contributing to severe complications after liver resection (SC) using an AggRCA. Methods This was a retrospective qualitative study aimed to identify the main patterns contributing to severe complications (SC). All consecutive SC (Clavien-Dindo > 3a within the first 90 days after liver resection) that occurred between January 1st, 2018 and December 31st, 2019 were identified from a prospective electronic database and included in an AggRCA. This included a structured MMR (Morbidity and Mortality Review) reporting tool based on 50 contributory factors adapted from 6 ALARM categories: “Patient”, “Tasks”, “Individual staff”, “Team”, “Work environment”, and “Management and Institutional context”. Data resulting from individual-participant RCA of single-cases were validated collectively then aggregated. The main patterns were suggested from the contributory factors reported in more than half of the cases. Results Among 105 consecutive liver resections, 15 cases (14.3%) including 5 deaths (4.8%) met the inclusion criteria. AggRCA resulted in the identification of 36 contributory factors. Eight contributory factors were reported in more than half of the cases and were compiled in three entangled patterns: (1) Disrupted perioperative process, (2) Unplanned intraoperative change, (3) Ineffective communication. Conclusion A pragmatic aggregated RCA process improved our understanding of system vulnerabilities based on the analysis of a limited number of events and a reasonable resource intensity. The identification of patterns contributing to SC lay the rationale of future contextualized safety interventions beyond the scope of liver resections.