Application of Fusion-Fluorescence Imaging Using Indocyanine Green in Endoscopic Endonasal Surgery: Preliminary Data
Abstract PurposeIndocyanine green (ICG) has been used in endoscopic surgery in the neurosurgical field, but it has been challenging to determine the associated efficiency due to limitations with visualization in the previous endoscopic system. A new endoscopic system was recently introduced; therefore, we summarize our experiences with the application and integration of the system.MethodsFrom March to May 2021, a newly introduced endoscopic system was used in 6 patients. (3 pituitary adenomas, 1 pituitary apoplexy, 2 tuberculum sellae meningiomas) and 12.5 mg of ICG was injected for each study.ResultsThree pituitary adenomas, including one acromegaly, were well identified with ICG. However, one pituitary apoplexy and two meningiomas were not visualized with ICG. Meanwhile, ICG appeared to be effective for determining the viability of nasoseptal mucosa.ConclusionICG provides real-time information during endoscopic endonasal surgery. We suggest that the pituitary adenoma can be stained with an ICG using the fusion-fluorescence imaging endoscopic system. This approach will enhance the surgeon’s ability to achieve gross total resection.