scholarly journals Application of Fusion-Fluorescence Imaging Using Indocyanine Green in Endoscopic Endonasal Surgery: Preliminary Data

Author(s):  
Min Ho Lee ◽  
Tae-Kyu Lee

Abstract PurposeIndocyanine green (ICG) has been used in endoscopic surgery in the neurosurgical field, but it has been challenging to determine the associated efficiency due to limitations with visualization in the previous endoscopic system. A new endoscopic system was recently introduced; therefore, we summarize our experiences with the application and integration of the system.MethodsFrom March to May 2021, a newly introduced endoscopic system was used in 6 patients. (3 pituitary adenomas, 1 pituitary apoplexy, 2 tuberculum sellae meningiomas) and 12.5 mg of ICG was injected for each study.ResultsThree pituitary adenomas, including one acromegaly, were well identified with ICG. However, one pituitary apoplexy and two meningiomas were not visualized with ICG. Meanwhile, ICG appeared to be effective for determining the viability of nasoseptal mucosa.ConclusionICG provides real-time information during endoscopic endonasal surgery. We suggest that the pituitary adenoma can be stained with an ICG using the fusion-fluorescence imaging endoscopic system. This approach will enhance the surgeon’s ability to achieve gross total resection.

2019 ◽  
Author(s):  
Bakhtiyar Pashaev ◽  
Liliya Hisanova ◽  
Dmitriy Bochkarev ◽  
Valeriy Danilov ◽  
Andrey Alekseev ◽  
...  

Skull Base ◽  
2011 ◽  
Vol 21 (S 01) ◽  
Author(s):  
Samuel Shin ◽  
Matthew Tormenti ◽  
Sue Challinor ◽  
Tian Wang ◽  
Juan Fernandez-Miranda ◽  
...  

2013 ◽  
Vol 11 (3) ◽  
pp. 227-241 ◽  
Author(s):  
Srinivas Chivukula ◽  
Maria Koutourousiou ◽  
Carl H. Snyderman ◽  
Juan C. Fernandez-Miranda ◽  
Paul A. Gardner ◽  
...  

Object The use of endoscopic endonasal surgery (EES) for skull base pathologies in the pediatric population presents unique challenges and has not been well described. The authors reviewed their experience with endoscopic endonasal approaches in pediatric skull base surgery to assess surgical outcomes and complications in the context of presenting patient demographics and pathologies. Methods A retrospective review of 133 pediatric patients who underwent EES at our institution from July 1999 to May 2011 was performed. Results A total of 171 EESs were performed for skull base tumors in 112 patients and bony lesions in 21. Eighty-five patients (63.9%) were male, and the mean age at the time of surgery was 12.7 years (range 2.3–18.0 years). Skull base tumors included angiofibromas (n = 24), craniopharyngiomas (n = 16), Rathke cleft cysts (n = 12), pituitary adenomas (n = 11), chordomas/chondrosarcomas (n = 10), dermoid/epidermoid tumors (n = 9), and 30 other pathologies. In total, 19 tumors were malignant (17.0%). Among patients with follow-up data, gross-total resection was achieved in 16 cases of angiofibromas (76.2%), 9 of craniopharyngiomas (56.2%), 8 of Rathke cleft cysts (72.7%), 7 of pituitary adenomas (70%), 5 of chordomas/chondrosarcomas (50%), 6 of dermoid/epidermoid tumors (85.7%), and 9 cases of other pathologies (31%). Fourteen patients received adjuvant radiotherapy, and 5 received chemotherapy. Sixteen patients (15.4%) showed tumor recurrence and underwent reoperation. Bony abnormalities included skull base defects (n = 12), basilar invagination (n = 4), optic nerve compression (n = 3) and trauma (n = 2); preexisting neurological dysfunction resolved in 12 patients (57.1%), improved in 7 (33.3%), and remained unchanged in 2 (9.5%). Overall, complications included CSF leak in 14 cases (10.5%), meningitis in 5 (3.8%), transient diabetes insipidus in 8 patients (6.0%), and permanent diabetes insipidus in 12 (9.0%). Five patients (3.8%) had transient and 3 (2.3%) had permanent cranial nerve palsies. The mean follow-up time was 22.7 months (range 1–122 months); 5 patients were lost to follow-up. Conclusions Endoscopic endonasal surgery has proved to be a safe and feasible approach for the management of a variety of pediatric skull base pathologies. When appropriately indicated, EES may achieve optimal outcomes in the pediatric population.


2018 ◽  
Vol 29 (1) ◽  
pp. e83-e87 ◽  
Author(s):  
Lei Li ◽  
Xiaoye Ma ◽  
Sajan Pandey ◽  
Aoyuan Fan ◽  
Xianyu Deng ◽  
...  

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